COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,137 Articles (22,693 medRxiv, 8,444 bioRxiv)

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A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein
Riojas, M. A., Frank, A. M., Puthuveetil, N. P., Flores, B., Parker, M., King, S. P., Peiris, M., Chu, D. K. W., Benton, B., Bradford, R., Hazbon, M. H., Rashid, S.
10.1101/2020.06.09.134460 — Posted: 2020-06-10
The utility of native MS for understanding the mechanism of action of repurposed therapeutics in COVID-19: heparin as a disruptor of the SARS-CoV-2 interaction with its host cell receptor.
Yang, Y., Du, Y., Kaltashov, I. A.
10.1101/2020.06.09.142794 — Posted: 2020-06-10
Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy
Caldas, L. A., Carneiro, F. A., Higa, L. M., Monteiro, F. L., da Silva, G. P., Costa, L. J. d., Durigon, E. L., Tanuri, A., de Souza, W.
10.1101/2020.06.10.144642 — Posted: 2020-06-10
Age-dependent progression of SARS-CoV-2 infection in Syrian hamsters
Osterrieder, N., Bertzbach, L. D., Dietert, K., Abdelgawad, A., Vladimirova, D., Kunec, D., Hoffmann, D., Beer, M., Gruber, A. D., Trimpert, J.
10.1101/2020.06.10.144188 — Posted: 2020-06-10 Discussion: Onsite | Offsite
SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins
Perdikari, T. M., Murthy, A. C., Ryan, V. H., Watters, S., Naik, M. T., Fawzi, N. L.
10.1101/2020.06.09.141101 — Posted: 2020-06-10 Discussion: Onsite
Fast isolation of sub-nanomolar affinity alpaca nanobody against the Spike RBD of SARS-CoV-2 by combining bacterial display and a simple single-step density gradient selection
Valenzuela Nieto, G. E., Jara, R., Himelreichs, J., Salinas, C., Pinto, T., Cheuquemilla, Y., Margolles, Y., Lopez Gonzalez del Rey, N., Miranda Chacon, Z., Cuevas, A., Berking, A., Deride, C., Gonzalez-Moraga, S., Mancilla, H., Maturana, D., Langer, A., Toledo, J. P., Müller, A., Uberti, B., Krall, P., Ehrenfeld, P., Blesa, J., Chana-Cuevas, P., Rehren, G., Fernandez, L. A., Rojas-Fernandez, A.
10.1101/2020.06.09.137935 — Posted: 2020-06-10
The impact of viral transport media on PCR assay results for the detection of nucleic acid from SARS-CoV-2 and other viruses
Kirkland, P. D., Frost, M. J.
10.1101/2020.06.09.142323 — Posted: 2020-06-10
Evaluating the efficacy of RT-qPCR SARS-CoV-2 direct approaches in comparison to RNA extraction
Israeli, O., Beth-Din, A., Paran, N., Stein, D., Lazar, S., Weiss, S., Milrot, E., Atiya-Nasagi, Y., Yitzhaki, S., Laskar, O., Schuster, O.
10.1101/2020.06.10.144196 — Posted: 2020-06-10
Prolonged SARS-CoV-2 Viral Shedding in Patients with COVID-19 was Associated with Delayed Initiation of Arbidol Treatment: a retrospective cohort study
Zhou, Y., He, X., Zhang, J., Xue, Y. e., Liang, M., Yang, B., Ma, W., Zhou, Q., Chen, L., Wang, X.
10.1101/2020.06.09.20076646 — Posted: 2020-06-10
Stability of SARS-CoV-2 Phylogenies
Turakhia, Y., Thornlow, B., Gozashti, L., Hinrichs, A., Fernandes, J., Haussler, D., Corbett-Detig, R.
10.1101/2020.06.08.141127 — Posted: 2020-06-09

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).