COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,283 Articles (22,759 medRxiv, 8,524 bioRxiv)

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Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 human coronavirus in vitro.
French, C. T.
10.1101/2020.11.12.380394 — Posted: 2020-11-12
Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD
Mehedi, M., Osan, J. K., Talukdar, S. N., Feldmann, F., DeMontigny, B. A., Jerome, K., Bailey, K. L., Feldmann, H.
10.1101/2020.11.11.379099 — Posted: 2020-11-12
Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease
Guenther, S., Reinke, P. Y. A., Fernandez-Garcia, Y., Lieske, J., Lane, T. J., Ginn, H., Koua, F., Ehrt, C., Ewert, W., Oberthuer, D., Yefanov, O., Meier, S., Lorenzen, K., Krichel, B., Kopicki, J., Gelisio, L., Brehm, W., Dunkel, I., Seychell, B., Gieseler, H., Norton-Baker, B., Escudero-Perez, B., Domaracky, M., Saouane, S., Tolstikova, A., White, T., Haenle, A., Groessler, M., Fleckenstein, H., Trost, F., Galchenkova, M., Gevorkov, Y., Li, C., Awel, S., Peck, A., Barthelmess, M., Schluenzen, F., Lourdu, X. P., Werner, N., Andaleeb, H., Ullah, N., Falke, S., Srinivasan, V., Franca, B., Schwinzer, M., Brognaro, H., Rogers, C., Melo, D., Doyle, J. J., Knoska, J., Pena Murillo, G. E., Rahmani Mashhour, A., Guicking, F., Hennicke, V., Fischer, P., Hakanpaeae, J., Meyer, J., Gribbon, P., Ellinger, B., Kuzikov, M., Wolf, M., Borenkov, G., von Stetten, D., Pompidor, G., Bento, I., Panneerselvam, S., Karpics, I., Schneider, T. R., Garcia Alai, M., Niebling, S., Guenther, C., Schmidt, C., Schubert, R., Han, H., Boger, J., Monteiro, D., Zhang, L., Sun, X., Pletzer-Zelgert, J., Wollenhaupt, J., Feiler, C., Weiss, M. S., Schulz, E. C., Mehrabi, P., karnicar, k., Usenik, A., loboda, j., Tidow, H., chari, A., Hilgenfeld, R., Uetrecht, C., Cox, R., Zaliani, A., Beck, T., Rarey, M., Guenther, S., Turk, D., Hinrichs, W., Chapman, H. N., Pearson, A. R., Betzel, C., Meents, A.
10.1101/2020.11.12.378422 — Posted: 2020-11-12
Bifurcations and mutation hot-spots in the SARS-CoV-2 spike protein
Niemi, A. J., Peng, X.
10.1101/2020.11.11.378828 — Posted: 2020-11-12
Identifying and prioritizing potential human-infecting viruses from their genome sequences
Mollentze, N., Babayan, S., Streicker, D.
10.1101/2020.11.12.379917 — Posted: 2020-11-12
Nanodroplet-Benzalkonium Chloride Formulation Demonstrates In Vitro and Ex Vivo Broad-Spectrum Antiviral Activity Against SARS-CoV-2 and Other Enveloped Viruses
Pannu, J., Ciotti, S., Ganesan, S., Arida, G., Costley, C., Fattom, A. I.
10.1101/2020.11.12.377598 — Posted: 2020-11-12
Neuraminidase inhibitors rewire neutrophil function in murine sepsis and COVID-19 patient cells
Formiga, R. O., Amaral, F. C., Souza, C. F., Mendes, D. A. G. B., Wanderley, C. W. S., Lorenzini, C. B., Santos, A. A., Antonia, J., Faria, L. F., Natale, C. C., Paula, N. M., Silva, P. C. S., Fonseca, F. R., Aires, L., Heck, N., Barroso, S. P. C., Morrot, A., Sordi, R., Alisson-Silva, F., Mansur, D. S., Cunha, F. Q., Maurici, R., Bafica, A., Macauley, M. S., Spiller, F.
10.1101/2020.11.12.379115 — Posted: 2020-11-12
ACE2-Targeting Monoclonal Antibody As A "Pan" Coronavirus Blocker In Vitro and In A Mouse Model
Chen, Y., Zhang, Y., Yan, R., Wang, G., Zhang, Y., Zhang, Z., Li, Y., Chu, W., Chen, Y., Chen, G., Wang, Q., Zhou, Q., Zhang, B., Wang, C.
10.1101/2020.11.11.375972 — Posted: 2020-11-12
Combined in silico docking and in vitro antiviral testing for drug repurposing identified lurasidone and elbasvir as SARS-CoV-2 and HCoV-OC43 inhibitors
Milani, M., Donalisio, M., Bonotto, R. M., Schneider, E., Arduino, I., Boni, F., Lembo, D., Marcello, A., Mastrangelo, E.
10.1101/2020.11.12.379958 — Posted: 2020-11-12
Molecular Mimicry Map (3M) of SARS-CoV-2: Prediction of potentially immunopathogenic SARS-CoV-2 epitopes via a novel immunoinformatic approach
An, H., Park, J.
10.1101/2020.11.12.344424 — Posted: 2020-11-12

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).