COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,973 Articles (22,604 medRxiv, 8,369 bioRxiv)

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SARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential
Vithani, N., Ward, M. D., Zimmerman, M. I., Novak, B., Borowsky, J. H., Singh, S., Bowman, G. R.
10.1101/2020.12.10.420109 — Posted: 2020-12-10
Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion
Plaper, T., Aupic, J., Dekleva, P., Lapenta, F., Mancek, M., Jerala, R., Bencina, M.
10.1101/2020.12.10.419440 — Posted: 2020-12-10
An interactive viral genome evolution network analysis system enabling rapid large-scale molecular tracing of SARS-CoV-2
Ling, Y., Cao, R., Qian, J., Li, J., Zhou, H., Yuan, L., Wang, Z., Zheng, G., Zhao, G., Li, Y., Wang, Z., Zhang, G.
10.1101/2020.12.09.417121 — Posted: 2020-12-10
Betulonic acid derivatives inhibiting coronavirus replication in cell culture via the nsp15 endoribonuclease
Krasniqi, B., Stevaert, A., Van Loy, B., Nguyen, T., Thomas, J., Vandeput, J., Jochmans, D., Thiel, V., Dijkman, R., Dehaen, W., Voet, A., Naesens, L.
10.1101/2020.12.10.418996 — Posted: 2020-12-10
Molnupiravir (EIDD-2801) inhibits SARS-CoV2 replication in Syrian hamsters model
Abdelnabi, R., Foo, C. S., Kaptein, S. J. F., Zhang, X., Langendries, L., Vangeel, L., Vergote, V., Heylen, E., Dallmeier, K., Chatterjee, A., De Jonghe, S., Weynand, B., Neyts, J.
10.1101/2020.12.10.419242 — Posted: 2020-12-10
A single dose, BCG-adjuvanted SARS-CoV-2 vaccine induces Th1-polarized immunity and high-titre neutralizing antibodies in mice
Counoupas, C., Stella, A., Bhattacharyya, N., Grey, A., Patel, K., Ferguson, A., Hutchings, O., Feng, C., Palendira, U., Steain, M., Aggarwal, A., Low, J., Mackay, J., Kelleher, A., Britton, W., Turville, S., Triccas, J. A.
10.1101/2020.12.10.419044 — Posted: 2020-12-10
SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray
Pyrc, K., Milewska, A., Duran, E. B., Botwina, P., Lopes, R., Arenas-Pinto, A., Badr, M., Mellor, R., Kalber, T., Fernandez-Reyes, D., Schatzlein, A. G., Uchegbu, I. F.
10.1101/2020.12.10.413609 — Posted: 2020-12-10
Social Media Insights Into US Mental Health Amid the COVID-19 Pandemic. A Longitudinal Twitter Analysis (JANUARY-APRIL 2020)
Valdez, D., ten Thij, M., Bathina, K. C., Rutter, L. A., Bollen, J.
10.1101/2020.12.01.20241943 — Posted: 2020-12-10
The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike
Guo, C., Tsai, S. J., Ai, Y., Li, M., Pekosz, A., Cox, A., Atai, N., Gould, S.
10.1101/2020.12.08.417022 — Posted: 2020-12-09
Characterization of protease activity of Nsp3 from SARS-CoV-2 and its in vitro inhibition by nanobodies
Armstrong, L., Lange, S. M., de Cesare, V., Matthews, S. P., Nirujogi, R. S., Cole, I., Hope, A., Cunningham, F., Toth, R., Mukherjee, R., Bojkova, D., Gruber, F., Gray, D., Wyatt, P. G., Cinatl, J., Dikic, I., Davies, P., Kulathu, Y.
10.1101/2020.12.09.417741 — Posted: 2020-12-09

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).