COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,284 Articles (22,759 medRxiv, 8,525 bioRxiv)

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Computational Analysis of Protein Stability and Allosteric Interaction Networks in Distinct Conformational Forms of the SARS-CoV-2 Spike D614G Mutant: Reconciling Functional Mechanisms through Allosteric Model of Spike Regulation
Verkhivker, G., Agajanian, S., Oztas, D., Gupta, G.
10.1101/2021.01.26.428331 — Posted: 2021-01-27
Lysosomal-Immune Axis Is Associated with COVID 19 Disease Severity: Insights from Patient Single Cell Data
Pande, R., Teeple, E., Huang, W., Klinger, K. W., Rajpal, D., Kumar, D.
10.1101/2021.01.27.428394 — Posted: 2021-01-27
E484K as an innovative phylogenetic event for viral evolution: Genomic analysis of the E484K spike mutation in SARS-CoV-2 lineages from Brazil
Ferrareze, P. A. G., Franceschi, V. B., Mayer, A. d. M., Caldana, G. D., Zimerman, R. A., Thompson, C. E.
10.1101/2021.01.27.426895 — Posted: 2021-01-27 Discussion: Onsite
Zinc supplement augments the suppressive effects of repurposed drugs of NF-kappa B inhibitor on ACE2 expression in human lung cell lines in vitro.
Lee, M. C., Chen, Y.-K., Hsu, Y.-J., Lin, B.-R.
10.1101/2021.01.27.428372 — Posted: 2021-01-27
An Updated Investigation Prior To COVID-19 Vaccination Program In Indonesia: Full-Length Genome Mutation Analysis Of SARS-CoV-2
Nidom, R. V., Indrasari, S., Normalina, I., Nidom, A. N., Afifah, B., Dewi, L., Putra, A. K., Ansori, A. N. M., Kusala, M. K. J., Alamudi, M. Y., Nidom, C. A.
10.1101/2021.01.26.426655 — Posted: 2021-01-27
Neutralization of spike 69/70 deletion, E484K, and N501Y SARS-CoV-2 by BNT162b2 vaccine-elicited sera
Xie, X., Liu, Y., Liu, J., Zhang, X., Zou, J., Fontes-Garfias, C. R., Xia, H., Swanson, K. A., Cutler, M., Cooper, D., Menachery, V. D., Weaver, S., Dormitzer, P., Shi, P.-Y.
10.1101/2021.01.27.427998 — Posted: 2021-01-27 Discussion: Onsite
Sequence signatures of two IGHV3-53/3-66 public clonotypes to SARS-CoV-2 receptor binding domain
Tan, T. J. C., Yuan, M., Kuzelka, K., Padron, G. C., Beal, J. R., Chen, X., Wang, Y., Rivera-Cardona, J., Zhu, X., Stadtmueller, B. M., Brooke, C. B., Wilson, I. A., Wu, N. C.
10.1101/2021.01.26.428356 — Posted: 2021-01-27
Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model
Caceres, C. J., Cardenas-Garcia, S., Carnaccini, S., Seibert, B., Rajao, D. S., Wang, J., Perez, D. R.
10.1101/2021.01.27.428428 — Posted: 2021-01-27
Low-Dose Ad26.COV2.S Protection Against SARS-CoV-2 Challenge in Rhesus Macaques
He, X., Chandrashekar, A., Zahn, R. C., Wegmann, F., Yu, J., Mercado, N. B., McMahan, K., Martinot, A. J., Piedra-Mora, C., Beecy, S., Ducat, S., Chamanza, R., Rosendahl Huber, S., van der Fits, L., Borducchi, E. N., Lifton, M., Liu, J., Nampanya, F., Patel, S., Peter, L., Tostanoski, L. H., Pessaint, L., Van Ry, A., Finneyfrock, B., Velasco, J., Teow, E., Brown, R., Cook, A., Andersen, H., Lewis, M. G., Schuitemaker, H., Barouch, D. H.
10.1101/2021.01.27.428380 — Posted: 2021-01-27
Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19
Tardif, J.-C., Bouabdallaoui, N., L'Allier, P. L., Gaudet, D., Shah, B., Pillinger, M. H., Lopez-Sendon, J., da Luz, P., Verret, L., Audet, S., Dupuis, J., Denault, A. Y., Pelletier, M., Tessier, P. A., Samson, S., Fortin, D., Tardif, J.-D., Busseuil, D., Goulet, E., Lacoste, C., Dubois, A., Joshi, A. Y., Waters, D. D., Hsue, P., Lepor, N. E., Lesage, F., Sainturet, N., Roy-Clavel, E., Bassevitch, Z., Orfanos, A., Gregoire, J. C., Busque, L., Lavallee, C., Hetu, P.-O., Paquette, J.-S., Levesque, S., Cossette, M., Nozza, A., Chabot-Blanchet, M., Dube, M.-P., Guertin, M.-C., Boivin, G.
10.1101/2021.01.26.21250494 — Posted: 2021-01-27 Discussion: Onsite | Offsite

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