COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,704 Articles (22,913 medRxiv, 8,791 bioRxiv)

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Possible link between higher transmissibility of B.1.617 and B.1.1.7 variants of SARS-CoV-2 and increased structural stability of its spike protein and hACE2 affinity
Kumar, V., Singh, J., Hasnain, S. E., Sundar, D.
10.1101/2021.04.29.441933 — Posted: 2021-04-29
Molecular interactions of the M and E integral membrane proteins of SARS-CoV-2
Monje-Galvan, V., Voth, G. A.
10.1101/2021.04.29.442018 — Posted: 2021-04-29
The natural stilbenoid (-)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7 and B.1.351 variants
Tietjen, I., Cassel, J., Register, E. T., Zhou, X. Y., Messick, T. E., Keeney, F., Lu, L. D., Beattie, K. D., Rali, T., Ertl, H. C., Salvino, J. M., Davis, R. A., Montaner, L. J.
10.1101/2021.04.29.442010 — Posted: 2021-04-29
Phylogenetic analysis of SARS-CoV-2 lineage development across the first and second waves in Eastern Germany, 2020
Yi, B., Poetsch, A. R., Stadtmueller, M., Rost, F., Winkler, S., Dalpke, A. H.
10.1101/2021.04.29.441906 — Posted: 2021-04-29
Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence
Ma, T., Ryu, H., McGregor, M., Babcock, B., Neidleman, J., Xie, G., George, A. F., Frouard, J., Murray, V., Gill, G., Ghosn, E., Newell, E., Lee, S., Roan, N.
10.1101/2021.04.28.441880 — Posted: 2021-04-29 Discussion: Onsite
Allelic variation in Class I HLA determines pre-existing memory responses to SARS-CoV-2 that shape the CD8+ T cell repertoire upon viral exposure
Francis, J. M., Leistritz-Edwards, D., Dunn, A., Tarr, C., Lehman, J., Dempsey, C., Hamel, A., Rayon, V., Liu, G., Wang, Y., Wille, M., Durkin, M., Hadley, K., Sheen, A., Roscoe, B., Ng, M., Rockwell, G., Manto, M., Gienger, E., Nickerson, J., MGH COVID-19 Collection and Processing Team, , Moarefi, A., Noble, M., Malia, T., Bardwell, P. D., Gordon, W., Swain, J., Skoberne, M., Sauer, K., Harris, T., Goldrath, A. W., Shalek, A. K., Coyle, A. J., Benoist, C., Pregibon, D. C.
10.1101/2021.04.29.441258 — Posted: 2021-04-29
An enveloped virus-like particle vaccine expressing a stabilized prefusion form of the SARS-CoV-2 spike protein elicits potent immunity after a single dose.
Fluckiger, A.-C., Ontsouka, B., Bozic, J., Diress, A., Ahmed, T., Berthoud, T., Liao, M., Tran, A., Duque, D., McCluskie, M., Diaz-Mitoma, F., Anderson, D. E., Soare, C.
10.1101/2021.04.28.441832 — Posted: 2021-04-29
Pyridostigmine in adults with severe SARS-CoV-2 infection: the PISCO trial
Fragoso-Saavedra, S., Nunez, I., Audelo-Cruz, B. M., Arias-Martinez, S., Manzur-Sandoval, D., Quintero-Villegas, A., Garcia-Gonzalez, H. B., Carbajal-Morelos, S. L., Ponce de Leon-Rosales, S., Gotes-Palazuelos, J., Caro-Vega, Y., Maza-Larrea, J., Batina, I., Islas-Weinstein, L., Calva, J. J., Iruegas-Nunez, D. A., Belaunzaran-Zamudio, P. F., Sierra-Madero, J., Crispin, J. C., Valdes-Ferrer, S. I.
10.1101/2021.04.28.21255834 — Posted: 2021-04-29
Estimating local outbreak risks and the effects of non-pharmaceutical interventions in age-structured populations: SARS-CoV-2 as a case study
Lovell-Read, F. A., Shen, S., Thompson, R. N.
10.1101/2021.04.27.21256163 — Posted: 2021-04-29
Rapidly increasing SARS-CoV-2 seroprevalence and limited clinical disease in three Malian communities: a prospective cohort study
Sagara, I., Woodford, J., Kone, M., Assadou, M. H., Katile, A., Attaher, O., Zeguime, A., Doucoure, M., Higbee, E., Lane, J., Doritchamou, J., Zaidi, I., Esposito, D., Kwan, J., Sadtler, K., Dicko, A., Duffy, P.
10.1101/2021.04.26.21256016 — Posted: 2021-04-29

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).