COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,184 Articles (22,713 medRxiv, 8,471 bioRxiv)

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Inactivation of SARS-CoV-2 by β-propiolactone Causes Aggregation of Viral Particles and Loss of Antigenic Potential
Gupta, D., Parthasarathy, H., Sah, V., Tandel, D., Vedagiri, D., Reddy, S., Harshan, K. H.
10.1101/2021.04.22.441045 — Posted: 2021-04-23
The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection
McDonald, J. T., Enguita, F. J., Taylor, D., Bowen, R. A., Griffin, R. J., Priebe, W., Emmett, M. R., McGrath, M., Sajadi, M., Harris, A. D., Clement, J., Dybas, J. M., Aykin-Burns, N., Guarnieri, J. W., Singh, L. N., Grabham, P., Baylin, S., Yousey, A., Pearson, A. N., Corry, P. M., Saravia-Butler, A., Aunins, T. R., Nagpal, P., Meydan, C., Foox, J., Mozsary, C., Cerqueira, B., Zaksas, V., Singh, U., Wurtele, E. S., Costes, S. V., Galeano, D., Paccanaro, A., Meinig, S. L., Hagan, R. S., Bowman, N. M., UNC COVID-19 Pathobiology Consortium, , Wolfgang, M. C., Altinok, S., Sapoval, N., Treangen, T. J., Frieman, M., Vanderburg, C., Schisler, J. C., Mason, C., Chatterjee, A., Meller, R., Beheshti, A.
10.1101/2021.04.23.441024 — Posted: 2021-04-23
Computational investigation reveals that the mutant strains of SARS-CoV2 are highly infectious than wildtype
Kumar, R., Kumar, R., Goel, H., Tanwar, P.
10.1101/2021.04.23.441125 — Posted: 2021-04-23
Gut microbiota diversity and C-Reactive Protein are predictors of disease severity in COVID-19 patients
Moreira-Rosario, A., Marques, C., Pinheiro, H., Araujo, J. R., Ribeiro, P., Rocha, R., Mota, I., Pestana, D., Ribeiro, R., Pereira, A., Jose de Sousa, M., Pereira-Leal, J., de Sousa, J., Morais, J., Teixeira, D., Rocha, J. C., Silvestre, M., Principe, N., Gatta, N., Amado, J., Santos, L., Maltez, F., Boquinhas, A., de Sousa, G., Germano, N., Sarmento, G., Granja, C., Povoa, P., Faria, A., Calhau, C.
10.1101/2021.04.20.440658 — Posted: 2021-04-23
Prefusion conformation of SARS-CoV-2 receptor-binding domain favors interactions with human receptor ACE2
Kumawat, N., Tucs, A., Bera, S., N. Chuev, G., Fedotova, M. V., Tsuda, K., Kruchinin, S. E., Sljoka, A., CHAKRABORTY, A.
10.1101/2021.04.22.441041 — Posted: 2021-04-23
Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection
Biering, S. B., Sarnik, S. A., Wang, E., Zengel, J. R., Sathyan, V., Nguyenla, X., Van Dis, E., Catamura, C., Yamashiro, L. H., Begeman, A., Stark, J. C., Shon, D. J., Fox, D. M., Puschnik, A. S., Bertozzi, C. R., Carette, J. E., Stanley, S. A., Harris, E., Konermann, S., Hsu, P. D.
10.1101/2021.04.22.440848 — Posted: 2021-04-23
Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated primary human airway cells
Guo, W., Porter, L. M., Crozier, T. W., Coates, M., Jha, A., McKie, M., Nathan, J. A., Lehner, P. J., Greenwood, E. J., McCaughan, F.
10.1101/2021.04.23.440619 — Posted: 2021-04-23
Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees
Yadav, P., Sapkal, G. N., Abraham, P., Ella, R., Deshpande, G., Patil, D. Y., Nyayanit, D., Gupta, N., Sahay, R. R., Shete, A. M., Panda, S., Bhargava, B., Mohan, V. K.
10.1101/2021.04.23.441101 — Posted: 2021-04-23 Discussion: Onsite
Resolutive results with oral corticosteroids for patients with COVID-19 in pulmonary inflammatory phase. Successful outpatient experience during the collapse of Belem do Para Health System - Brazil.
Zeballos, R. S., Cruz, L. N. L., Brilhante, V. C. R., Lima, A. V., Martins, C. L. L. P., Lima, K. N. A., Leao, M. C. G. L., Cruz, B. L., Dysarz, A. B., Lobato, P. C. B., Almeida, E. S., Costa, R. A. P., Araujo, K. C., Almeida, A. C. C., Junior, L. B. D., Harada, K. O., Araujo, R. H. V. S., Prestes, E. X., Souza, I. M. S., Pereira, A. M. P., Rocha, A. B. M. A., Estevao, I. A., Carvalho, F. I. C., Melo, P. M. P.
10.1101/2021.04.19.20219949 — Posted: 2021-04-23 Discussion: Onsite
Large-scale analysis of synonymous viral variants reveals global adaptation of the SARS-CoV-2 to the human codon usage
Ramazzotti, D., Angaroni, F., Maspero, D., Mauri, M., D'Aliberti, D., Antoniotti, M., Graudenzi, A., Piazza, R.
10.1101/2021.04.23.441151 — Posted: 2021-04-23

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).