COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,705 Articles (22,913 medRxiv, 8,792 bioRxiv)

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Modeling viral and bacterial infections in human lung organotypic systems reveals strain specific host responses
Faria Fonseca, B., Wong-Ng, J., Connor, M., Mary, H., Kim, M. H., Yim, R., BONDET, V., Michel, V., Strick Marchand, H., Di Santo, J. P., Duffy, D., Hamon, M. A., Sauvonnet, N., Chakrabarti, L. A., Gobaa, S.
10.1101/2025.03.31.644992 — Posted: 2025-04-01
A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding
Hess, S., Campos-Alonso, M., Brand, M., Lauw, S., Lindenmann, U., Goebel, K., Geurink, P. P., Fritz, G., Riedl, R., Knobeloch, K.-P.
10.1101/2025.03.30.646166 — Posted: 2025-04-01
Divalent cations govern the activity of coronavirus nsp15
Wang, X., Li, J., Liu, Z., Wang, L., Zhu, B.
10.1101/2025.03.29.646087 — Posted: 2025-03-31
Functional and structural characterization of a combination of pan-sarbecovirus antibodies with potent antiviral activity
Marden, G. C., Schmitt, K. P., Zimmerman, M. I., Ramos, A. H., Menzenski, M. Z., Sharma, G., Li, H., Carlin, E., Jecrois, A., Morales-Perez, C. L., Palovcak, E., Garlick, J. D., Hannigan, B., Russell, P., Federman, R. S., Leung, A., Vargas, N. L., Shaban, N. M., Vaidya, V., Towler, H., Joh, N. H., Lord, D. M., Tao, J., Costello, Z., Frappier, V., Hopson, K., Pegu, A., Koh, G. C. K. W., Van Epps, H., Root, A., Grigoryan, G., Hazuda, D., Borriello, F.
10.1101/2025.03.30.646023 — Posted: 2025-03-31
The CCR2 inflammatory pathway is a target for improving severe disease and pulmonary inflammation in experimental COVID-19
Kazungu, Y., Hegde, S., Sharma, P., Marriott, A., Steven, A., Reine, J., Dagley, J. L., Mack, M., Stewart, J. P., Turner, J. D.
10.1101/2025.03.28.645941 — Posted: 2025-03-31
Gut barrier integrity biomarkers are associated with increased inflammation and predict disease status in hospitalized COVID-19 patients
Basting, C. M., Schroeder, T., Ferbas, K., Shields-Cutler, R., Tobin, N., Velez, A., Swanson, E., Broedlow, C. A., Langat, R., Schifanella, L., Bramante, C. T., Aldrovandi, G. M., Rimoin, A., Yang, O. O., Fulcher, J. A., Klatt, N. R.
10.1101/2025.03.28.645914 — Posted: 2025-03-31
Immuno-functionomics reveals geographical variation and a role for TLR8 in mRNA vaccine responses
Huisman, W., Azimi, S., Nguyen, Y. N., de Kroon, A. C., de Ruiter, K., Tahapary, D. L., Manurung, M. D., Pothast, C. R., Kruize, Y. C. M., Heemskerk, M. H. M., Supali, T., Visser, L. G., Roukens, A. H. E., Yazdanbakhsh, M., Jochems, S. P.
10.1101/2025.03.28.645987 — Posted: 2025-03-31
Biophysical fitness landscape design traps viral evolution
Mohanty, V., Shakhnovich, E. I.
10.1101/2025.03.30.646233 — Posted: 2025-03-31
Performance characteristics of the SARS-CoV-2 Isothermal Molecular Assay for point-of-care molecular diagnosis of SARS-CoV-2
Onwuamah, C. K., Shaibu, J. O., Amoo, S. O., Ahmed, A.-R. A., Abimbola, B. S., Audu, R. A., Salako, B. L.
10.1101/2025.03.29.25324880 — Posted: 2025-03-30
Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study
Zhang, B., Wu, Q., Jhaveri, R., ZHOU, T., Becich, M. J., Bisyuk, Y., Blancero, F., Chrischilles, E. A., Chuang, C. H., Cowell, L. G., Fort, D., Horowitz, C. R., Kim, S., Ladino, N., Liebovitz, D. M., Liu, M., Mosa, A. S. M., Schwenk, H. T., Suresh, S., Taylor, B. W., Williams, D. A., Morris, J. S., Forrest, C. B., Chen, Y.
10.1101/2025.03.28.25324858 — Posted: 2025-03-30

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