COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,694 Articles (22,913 medRxiv, 8,781 bioRxiv)

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Discovery of RdRp Thumb-1 as a novel broad-spectrum antiviral family of targets and MDL-001 as a potent broad-spectrum inhibitor thereof - Part I: A Bioinformatics and Deep Learning Approach
Woods, V., Umansky, T., Ramesh, N., Russell, S. M., Garvey, D., Smith, D. M., Haders, D.
10.1101/2024.03.29.587401 — Posted: 2024-04-03
Distal Protein-Protein Interactions Contribute to SARS-CoV-2 Main Protease Substrate Binding and Nirmatrelvir Resistance
Lewandowski, E. M., Zhang, X., Tan, H., Jaskolka-Brown, A., Kohaal, N., Frazier, A., Madsen, J. J., Jacobs, L. M. C., Wang, J., Chen, Y.
10.1101/2024.04.01.587566 — Posted: 2024-04-02
Mapping immunodominant sites on the MERS-CoV spike glycoprotein targeted by infection-elicited antibodies in humans
Addetia, A., Stewart, C., Seo, A. J., Sprouse, K. R., Asiri, A. Y., Al-Mozaini, M., Memish, Z. A., Alshukairi, A., Veesler, D.
10.1101/2024.03.31.586409 — Posted: 2024-04-02
Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process
Xia, Z., Zhang, B., Sun, L., Zhang, C., Ren, T., Zhao, X., Su, Y., Wang, Q., Zhang, T., He, B., Wu, L.-Y.
10.1101/2024.04.01.587649 — Posted: 2024-04-02
Single-cell analysis of lung epithelial cells reveals age and cell population-specific responses to SARS-CoV-2 infection in ciliated cells
Osborn, R. M., Anderson, C. S., Leach, J. R., Chu, C.-Y., Dewhurst, S., Mariani, T. J., Thakar, J.
10.1101/2024.04.02.587663 — Posted: 2024-04-02
CovTransformer: A transformer model for SARS-CoV-2 lineage frequency forecasting
Feng, Y., Goldberg, E. E., Kupperman, M., Zhang, X., Lin, Y., Ke, R.
10.1101/2024.04.01.24305089 — Posted: 2024-04-01
Older Age and Vaccination Protect Against Transaminase Elevation in Pediatric SARS-CoV2
Fernandez Ovalle, A., Charles, C., Rosenbaum, J. E., Villalba Davila, P., Mora, M., Sharma, S., Vega, V., Khandakar, S., Wallach, T.
10.1101/2024.04.01.24303996 — Posted: 2024-04-01
Robotic-inspired approach to multi-domain membrane receptor conformation space: theory and SARS-CoV-2 spike protein case study
Mathew, A. T., Sikora, M., Hummer, G., Mehdipour, A. R.
10.1101/2024.03.29.587391 — Posted: 2024-04-01
ViRNN: A Deep Learning Model for Viral Host Prediction
Sphabmixay, P., Lash, B.
10.1101/2024.03.30.587436 — Posted: 2024-04-01
Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2
Ehling, R. A., Minot, M., Overath, M. D., Sheward, D. J., Han, J., Gao, B., Taft, J. M., Pertseva, M., Weber, C. R., Frei, L., Bikias, T., Murrell, B., Reddy, S. T.
10.1101/2024.03.28.587189 — Posted: 2024-04-01

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