COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,722 Articles (22,913 medRxiv, 8,809 bioRxiv)

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Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
Xu, C., Wang, Y., Liu, C., Zhang, C., Han, W., Hong, X., Wang, Y., Hong, Q., Wang, S., Zhao, Q., Wang, Y., Yang, Y., Chen, K., Zheng, W., Kong, L., Wang, F., Zuo, Q., Huang, Z., Cong, Y.
10.1101/2020.06.30.177097 — Posted: 2020-06-30
Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V., Mishra, S., Sharma, R., Agarwal, J., Ghoshal, U., Khanna, T., Sharma, L. K., Verma, S. K., Tiwari, S.
10.1101/2020.06.30.172833 — Posted: 2020-06-30 Discussion: Onsite
Validation and Comparison of a Modified CDC Assay with two Commercially Available Assays for the Detection of SARS-CoV-2 in Respiratory Specimen
Lima, A., Healer, V., Vendrone, E., Silbert, S.
10.1101/2020.06.29.179192 — Posted: 2020-06-30
SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 elicits immunogenicity in baboons and protection in mice
Tian, J.-H., Patel, N., Haupt, R., Zhou, H., Weston, S., Hammond, H., Lague, J., Portnoff, A. D., Norton, J., Guebre-Xabier, M., Zhou, B., Jacobson, K., Maciejewski, S., Khatoon, R., Wisniewska, M., Mottitt, W., Kluepfel-Stahl, S., Ekechukwu, B., Papin, J., Boddapati, S., Wong, C. J., Piedra, P. A., Frieman, M. B., Massare, M. J., Fries, L., Lovgren Bengtsson, K., Stertman, L., Ellingsworth, L. R., Glenn, G., Smith, G.
10.1101/2020.06.29.178509 — Posted: 2020-06-30 Discussion: Onsite
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies
Acharya, P., Williams, W., Henderson, R., Janowska, K., Manne, K., Parks, R., Deyton, M., Sprenz, J., Stalls, V., Kopp, M., Mansouri, K., Edwards, R. J., Meyerhoff, R., Oguin, T., Sempowski, G., Saunders, K. O., Haynes, B. F.
10.1101/2020.06.30.178897 — Posted: 2020-06-30
Genetic variants in TMPRSS2 and Structure of SARS-CoV-2 spike glycoprotein and TMPRSS2 complex
Vishnubhotla, R., Vankadari, N., Ketavarapu, V., Amanchy, R., Avanthi, S., Bale, G., Nageshwar Reddy, D., Sasikala, M.
10.1101/2020.06.30.179663 — Posted: 2020-06-30 Discussion: Onsite
Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
Mou, H., Quinlan, B., Peng, H., Guo, Y., Peng, S., Zhang, L., Davis-Gardner, M., Gardner, M., Voo, Z. X., Bailey, C. C., Alpert, M., Rader, C., Choe, H., Farzan, M.
10.1101/2020.06.29.178459 — Posted: 2020-06-30
Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs
Ren, L., Wu, C., Guo, L., Yao, J., Wang, C., Xiao, Y., Pisco, A. O., Wu, Z., Lei, X., Liu, Y., Shi, L., Han, L., Zhang, H., Xiao, X., Zhong, J., Wu, H., Li, M., Quake, S. R., Huang, Y., Wang, J., wang, j.
10.1101/2020.06.30.175778 — Posted: 2020-06-30 Discussion: Onsite | Offsite
A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection
Herrmann, A., Maruyama, J., Yue, C., Lahtz, C., Zhou, H., Kerwin, L., Guo, W., Zhang, Y., Soo Hoo, W., Yei, S., Kwon, S., Fu, Y., Johnson, S., Ledesma, A., Zhuang, Y., Zhuang, Y., Yei, E., Adamus, T., Praessler, S., Ji, H.
10.1101/2020.06.29.178616 — Posted: 2020-06-30 Discussion: Offsite
Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent
Hahn, G., Cho, M. H., Weiss, S. T., Silverman, E. K., Lange, C.
10.1101/2020.06.22.165936 — Posted: 2020-06-30 Discussion: Onsite

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