COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,363 Articles (22,803 medRxiv, 8,560 bioRxiv)

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Biochemical evidence of furin specificity and potential for phospho-regulation at Spike protein S1/S2 cleavage site in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV
Örd, M., Faustova, I., Loog, M.
10.1101/2020.06.23.166900 — Posted: 2020-06-23
SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
Klein, S., Cortese, M., Winter, S. L., Wachsmuth-Melm, M., Neufeldt, C. J., Cerikan, B., Stanifer, M. L., Boulant, S., Bartenschlager, R., Chlanda, P.
10.1101/2020.06.23.167064 — Posted: 2020-06-23
RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Subramanian, A., Vernon, K., Slyper, M., Waldman, J., Luecken, M. D., Gosik, K., Dubinsky, D., Cuoco, M., Keller, K., Purnell, J., Nguyen, L., Dionne, D., Rozenblatt-Rosen, O., Weins, A., Human Cell Atlas Lung Biological Network, , Regev, A., Greka, A.
10.1101/2020.06.23.167098 — Posted: 2020-06-23
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
Zhou, T., Teng, I.-T., Olia, A. S., Cerutti, G., Gorman, J., Nazzari, A., Shi, W., Tsybovsky, Y., Wang, L., Wang, S., Zhang, B., Zhang, Y., Katsamba, P. S., Petrova, Y., Banach, B. B., Fahad, A. S., Liu, L., Lopez Acevedo, S. N., Madan, B., Oliveira de Souza, M., Pan, X., Wang, P., Wolfe, J. R., Yin, M., Ho, D. D., Phung, E., DiPiazza, A., Chang, L., Abiona, O., Corbett, K. S., DeKosky, B. J., Graham, B. S., Mascola, J. R., Misasi, J., Ruckwardt, T., Sullivan, N. J., Shapiro, L., Kwong, P. D.
10.1101/2020.06.22.166033 — Posted: 2020-06-23 Discussion: Onsite | Offsite
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19
Shrimp, J. H., Kales, S. C., Sanderson, P. E., Simeonov, A., Shen, M., Hall, M. D.
10.1101/2020.06.23.167544 — Posted: 2020-06-23
Detailed phylogenetic analysis of SARS-CoV-2 reveals latent capacity to bind human ACE2 receptor
Anderson, D. W., Brintnell, E., Gupta, M.
10.1101/2020.06.22.165787 — Posted: 2020-06-23 Discussion: Onsite
CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells
Amraei, R., Napoleon, M., Yin, W., Berrigan, J., Suder, E., Zhao, G., Olejnik, J., Gummuluru, S., Muhlberger, E., Chitalia, V., Rahimi, N.
10.1101/2020.06.22.165803 — Posted: 2020-06-23
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Shi, P.-Y., Xie, X., Muruato, A. E., Zhang, X., Lokugamage, K. G., Fontes-Garfias, C. R., Zou, J., Liu, J., Ren, P., Balakrishnan, M., Cihlar, T., Tseng, C.-T. K., Makino, S., Menachery, V. D., Bilello, J. P.
10.1101/2020.06.22.165712 — Posted: 2020-06-23
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custodio, T. F., Das, H., Sheward, D. J., Hanke, L., Pazicky, S., Pieprzyk, J., Sorgenfrei, M., Schroer, M., Gruzinov, A., Jeffries, C., Graewert, M., Svergun, D. I., Dobrev, N., Remans, K., Seeger, M., McInerney, G. M., Murrell, B., Hällberg, B. M., Löw, C.
10.1101/2020.06.23.165415 — Posted: 2020-06-23
A graph-based approach identifies dynamic H-bond communication networks in spike protein S of SARS-CoV-2
Karathanou, K., Lazaratos, M., Bertalan, E., Siemers, M., Buzar, K., Schertler, G. F. X., del Val, C., Bondar, A.-N.
10.1101/2020.06.23.164947 — Posted: 2020-06-23

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).