COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,441 Articles (22,835 medRxiv, 8,606 bioRxiv)

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Single dose immunization with a COVID-19 DNA vaccine encoding a chimeric homodimeric protein targeting receptor binding domain (RBD) to antigen-presenting cells induces rapid, strong and long-lasting neutralizing IgG, Th1 dominated CD4+ T cells and strong CD8+ T cell responses in mice
Norheim, G., Stubsrud, E., Skullerud, L. M., Stankovic, B., Chellappa, S., Bjerkan, L., Kuczkowska, K., Muller, E., Sekelja, M., Fredriksen, A. B.
10.1101/2020.12.08.416875 — Posted: 2020-12-09
Pre-existing T cell-mediated cross-reactivity to SARS-CoV-2 cannot solely be explained by prior exposure to endemic human coronaviruses
Tan, C. C. S., Owen, C. J., Tham, C. Y. L., Bertoletti, A., van Dorp, L., Balloux, F.
10.1101/2020.12.08.415703 — Posted: 2020-12-09
Conformational diversity of CDR region during affinity maturation determines the affinity and stability of Sars-Cov-1 VHH-72 nanobody
George, S.
10.1101/2020.12.08.416164 — Posted: 2020-12-09
Identification of a Novel Susceptibility Marker for SARS-CoV-2 Infection in Human Subjects and Risk Mitigation with a Clinically Approved JAK Inhibitor in Human/Mouse Cells
Spalinger, M. R., Hai, R., Li, J., Santos, A. N., Nordgren, T. M., Tremblay, M. L., Eckmann, L., Hanson, E., Scharl, M., Wu, X., Boland, B. S., McCole, D. F.
10.1101/2020.12.09.416586 — Posted: 2020-12-09
Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study
Gabitzsch, E., Safrit, J. T., Verma, M., Rice, A., Sieling, P., Zakin, L., Shin, A., Morimoto, B., Adisetiyo, H., Wong, R., Bezawada, A., Dinkins, K., Balint, J., Peykov, V., Garban, H., Liu, P., Bacon, A., Drew, J., Spilman, P., Sender, L., Rabizadeh, S., Niazi, K., Soon-Shiong, P.
10.1101/2020.12.08.416297 — Posted: 2020-12-09 Discussion: Onsite
Persistent Cellular Immunity to SARS-CoV-2 Infection
Breton, G., Mendoza, P., Hagglof, T., Oliveira, T. Y., Schaefer-Babajew, D., Gaebler, C., Turroja, M., Hurley, A., Caskey, M., Nussenzweig, M. C.
10.1101/2020.12.08.416636 — Posted: 2020-12-09
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases
Tarke, A., Sidney, J., Kidd, C. K., Dan, J. M., Ramirez, S. I., Yu, E. D., Mateus, J., da Silva Antunes, R., Moore, E., Rubiro, P., Methot, N., Phillips, E. J., Mallal, S., Frazier, A., Rawlings, S., Greenbaum, J. A., Peters, B., Smith, D. M., Crotty, S., Weiskopf, D., Grifoni, A., Sette, A.
10.1101/2020.12.08.416750 — Posted: 2020-12-09
Positive correlation between long term emission of several air pollutants and COVID-19 deaths in Sweden
Helander, L.
10.1101/2020.12.05.20244418 — Posted: 2020-12-09
Role of favipiravir in the treatment of adult patients with moderate to severe COVID-19: a single-center, prospective, observational, sequential cohort study from Hungary
SZABO, B. G., LENART, K. S., PETRIK, B., GASPAR, Z., BALOGH, Z., BANYAI, Z., BANYASZ, E., BUDAI, J., CZEL, E., FRIED, K., HANUSKA, A., KISS-DALA, N., LORINCZI, C., NEMESI, K., KADAR, J., NAGY, E. L., OSVALD, A., PETROVICZ, E., RICZU, A., SZANKA, J., SZATHMARY, B., SZOMBATI, A., TOTH, S., VARNAI, Z., WOLLER, O., SZLAVIK, J., LAKATOS, B.
10.1101/2020.11.26.20238014 — Posted: 2020-12-09 Discussion: Onsite
Efficacy of pulmonary rehabilitation in severe and critical-ill COVID-19 patients: a controlled study
Buesching, G., Zhang, Z., Schmid, J. P., Sigrist, T., Khatami, R.
10.1101/2020.12.08.20245936 — Posted: 2020-12-09

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).