COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,442 Articles (22,835 medRxiv, 8,607 bioRxiv)

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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp12/7/8 RNA-dependent RNA Polymerase
Beale, R., Bertolin, A. P., Canal, B., Diffley, J. F., Drury, L. S., Howell, M., Milligan, J., Posse, V., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438807 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of nsp5 Main Protease
Basier, C., Beale, R., Bineva-Todd, G., Canal, B., Curran, J. F., Deegan, T. D., Diffley, J. F., Fujisawa, R., Howell, M., Joshi, D., Labib, K., Lim, C. T., Milligan, J., Nagaraj, H., O'Reilly, N., Papageorgiou, G., Soudy, C., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U.
10.1101/2021.04.07.438806 — Posted: 2021-04-08
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
Starr, T. N., Czudnochowski, N., Zatta, F., Park, Y.-J., Liu, Z., Addetia, A., Pinto, D., Beltramello, M., Hernandez, P., Greaney, A. J., Marzi, R., Glass, W. G., Zhang, I., Dingens, A. S., Bowen, J. E., Wojcechowskyj, J. A., De Marco, A., Rosen, L. E., Zhou, J., Montiel-Ruiz, M., Kaiser, H., Tucker, H., Housley, M. P., Di Iulio, J., Lombardo, G., Agostini, M., Sprugasci, N., Culap, K., Jaconi, S., Meury, M., Dellota, E., Cameroni, E., Croll, T. I., Nix, J. C., Havenar-Daughton, C., Telenti, A., Lempp, F. A., Pizzuto, M. S., Chodera, J. D., Hebner, C. M., Whelan, S. P., Virgin, H. W., Veesler, D., Corti, D., Bloom, J. D., Snell, G.
10.1101/2021.04.06.438709 — Posted: 2021-04-08
Functional evaluation of proteolytic activation for the SARS-CoV-2 variant B.1.1.7: role of the P681H mutation
Lubinski, B., Tang, T., Daniel, S., Jaimes, J. A., Whittaker, G.
10.1101/2021.04.06.438731 — Posted: 2021-04-08
Comparable environmental stability and disinfection profiles of the currently circulating SARS-CoV-2 variants of concern B.1.1.7 and B.1.351
Meister, T. L., Fortmann, J., Todt, D., Heinen, N., Ludwig, A., Brueggemann, Y., Elsner, C., Dittmer, U., Pfaender, S., Steinmann, E.
10.1101/2021.04.07.438820 — Posted: 2021-04-08 Discussion: Onsite
SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues including the heart and kidney
Francis, M., Goncin, U., Kroeker, A., Swan, C., Ralph, R., Lu, Y., Etzioni, A., Falzarano, D., Gerdts, V., Machtaler, S., Kindrachuk, J., Kelvin, A. A.
10.1101/2021.04.07.438843 — Posted: 2021-04-08
Mental health inequalities in healthcare, economic, and housing disruption during COVID -19: an investigation in 12 longitudinal studies
Di Gessa, G., Maddock, J., Green, M. J., Thompson, E. J., McElroy, E., Davies, H. L., Mundy, J., Stevenson, A. J., Kwong, A. S. F., Griffith, G. J., Katikireddi, S. V., Niedzwiedz, C. L., Ploubidis, G. B., Fitzsimons, E., Henderson, M., Silverwood, R. J., Chaturvedi, N., Breen, G., Steves, C. J., Steptoe, A., Porteous, D. J., Patalay, P.
10.1101/2021.04.01.21254765 — Posted: 2021-04-07
Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2
Deepak, P., Kim, W., Paley, M. A., Yang, M., Carvidi, A. B., El-Qunni, A. A., Haile, A., Huang, K., Kinnett, B., Leibeskind, M. J., Liu, Z., McMorrow, L. E., Paez, D., Perantie, D. C., Schriefer, R. E., Sides, S., Thapa, M., Gergely, M., Abushamma, S., Kelbert, M., Mitchell, L., Nix, B., Graf, J. D., Taylor, K. E., Chahin, S., Ciorba, M. A., Katz, P. A., Matloubian, M., O'Halloran, J. A., Presti, R. M., Wu, G. F., Whelan, S. P., Buchser, W. J., Gensler, L. S., Nakamura, M. C., Ellebedy, A. H., Kim, A. H.
10.1101/2021.04.05.21254656 — Posted: 2021-04-07 Discussion: Onsite
Effectiveness of CoronaVac in the setting of high SARS-CoV-2 P.1 variant transmission in Brazil: A test-negative case-control study
Hitchings, M., Ranzani, O. T., Torres, M. S. S., de Oliveira, S. B., Almiron, M., Said, R., Borg, R., Schulz, W. L., de Oliveira, R. D., da Silva, P. V., de Castro, D. B., Sampaio, V. d. S., de Albuquerque, B. C., Ramos, T. C. A., Fraxe, S. H. H., da Costa, C. F., Naveca, F. G., Siqueira, A. M., de Araujo, W. N., Andrews, J. R., Cummings, D. A. T., Ko, A. I., Croda, J.
10.1101/2021.04.07.21255081 — Posted: 2021-04-07 Discussion: Offsite
Increased vulnerability to SARS-CoV-2 infection among indigenous people living in the urban area of Manaus
Soares Pontes, G., de Melo Silva, J., Pinheiro-Silva, R., Nogueira Barbosa, A., Cardenes Santos, L., de Padua Quirino Ramalho, A., de Castro Alves, C. E., Furtado da Silva, D., Calheiros de Oliveira, L., Guimaraes da Costa, A., Bruno, A. C.
10.1101/2021.04.05.21254937 — Posted: 2021-04-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).