COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,704 Articles (22,913 medRxiv, 8,791 bioRxiv)

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Construction and characterization of coronavirus nonstructural protein 3-host protein interaction networks unravel an important role of cleavage and polyadenylation specificity factor 6 in regulation of viral RNA replication
Sun, X., Yuan, L. X., Hu, Z., Lai, Y., Yang, B., He, J., Chen, R., Liu, D.
10.1101/2025.02.27.640555 — Posted: 2025-02-28
Discovery of The Clinical Candidate S-892216: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19
Unoh, Y., Hirai, K., Uehara, S., Kawashima, S., Nobori, H., Sato, J., Shibayama, H., Hori, A., Nakahara, K., Kurahashi, K., Takamatsu, M., Yamamoto, S., Zhang, Q., Tanimura, M., Dodo, R., Maruyama, Y., Sawa, H., Watari, R., Miyano, T., Kato, T., Sato, T., Tachibana, Y.
10.1101/2025.02.26.639208 — Posted: 2025-02-28
Dynamics of natural selection preceding human viral epidemics and pandemics.
Havens, J. L., Pond, S. L. K., Zehr, J., Pekar, J. E., Parker, E., Worobey, M., Andersen, K. G., Wertheim, J. O.
10.1101/2025.02.26.640439 — Posted: 2025-02-28
The impact of Intensive Care Strain on Patients Outcomes during COVID-19 - a UNITE COVID study
Kohler, K., De Corte, T., Greco, M., Povoa, P., Cecconi, M., Ostermann, M., De Waele, J., Conway Morris, A., UNITE-COVID investigators
10.1101/2025.02.27.25322947 — Posted: 2025-02-27
Structural and Conformational Impact of Deleterious Spike Protein Mutations in SARS-CoV-2 Omicron Lineages
Khalid, A., Ahmed, K., Kanji, A., Munir, T., Bukhari, A. R., Hasan, Z., Van Voorhis, W., Iqbal, N. T.
10.1101/2025.02.25.639252 — Posted: 2025-02-27
Impact of cell culture model systems on SARS-CoV-2 and MERS-CoV infection dynamics and antiviral responses
Chiok, K., Fenton, M., Falzarano, D., Dhar, N., Banerjee, A.
10.1101/2025.02.24.639954 — Posted: 2025-02-27
Unveiling the Complete Spectrum of SARS-CoV-2 Fusion Stages by In Situ Cryo-ET
Akil, C., Xu, J., Shen, J., zhang, p.
10.1101/2025.02.25.640151 — Posted: 2025-02-27
Changes in somatic symptoms among people with severe COVID anxiety, before and after the coronavirus pandemic
Grocott, L., King, J. D., Mcquaid, A., Leeson, V. C., Crawford, M. J.
10.1101/2025.02.26.25322939 — Posted: 2025-02-26
A truncated SARS-CoV-2 nucleocapsid protein enhances virus fitness by evading antiviral responses
Mulloy, R. P., Evseev, D., Bui-Marinos, M. P., Sharlin, N., Corcoran, J. A.
10.1101/2025.02.15.638421 — Posted: 2025-02-26
Forecasting protein evolution by integrating birth-death population models with structurally constrained substitution models
Ferreiro, D., Gonzalez-Vazquez, L. D., Prado-Comesana, A., Arenas, M.
10.1101/2025.02.21.639428 — Posted: 2025-02-26

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).