COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,137 Articles (22,693 medRxiv, 8,444 bioRxiv)

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Single-shot rAAV5-based Vaccine Provides Long-term Protective Immunity against SARS-CoV-2 and Its Variants
Liao, G., Fan, x.-x., Lau, H., Liu, Z., Li, C., Xu, Z., Zhang, Y., Qi, X., Li, D., Zhu, Q., Chen, L., ZHOU, H., Zhu, S., Ke, B., Pan, H., Cong, Z., Li, Y., Feng, Q., Lv, Q., Liu, J., Liang, D., Li, A., Hong, W., Li, Y., Bao, L., Zhou, F., Gao, H., liang, s., Huang, B., Wu, M., Qin, C., Ke, C., liu, l.
10.1101/2021.08.23.456471 — Posted: 2021-08-26
Directing an mRNA-LNP vaccine toward lymph nodes improves humoral and cellular immunity against SARS-CoV-2
Francis, D. M., Chen, R., Khorsandzadeh, S., Hu, Q., Lyu, X., Wang, H., Lim, W.-l., Sun, H., Xie, H., Shaabani, N., Ross, R., Cooley, B., Ji, H.
10.1101/2021.08.25.457699 — Posted: 2021-08-25
Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization
Kim, Y., Gaudreault, N. N., Meekins, D. A., Perera, K. D., Bold, D., Trujillo, J. D., Morozov, I., McDowell, C. D., Chang, K.-O., Richt, J. A.
10.1101/2021.08.25.457627 — Posted: 2021-08-25
The B.1.427/1.429 (epsilon) SARS-CoV-2 variants are more virulent than ancestral B.1 (614G) in Syrian hamsters
Carroll, T., Fox, D., van Doremalen, N., Ball, E., Morris, M. K., Sotomayor-Gonzalez, A., Servellita, V., Rustagi, A., Yinda, C. K., Fritts, L., Port, J. R., Ma, Z.-M., Holbrook, M., Schulz, J., Blish, C. A., Hanson, C., Chiu, C. Y., Munster, V., Stanley, S., Miller, C. J.
10.1101/2021.08.25.457626 — Posted: 2021-08-25
Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate
Chen, W.-H., Pollet, J., Strych, U., Lee, J., Liu, Z., Kundu, R. T., Versteeg, L., Villar, M. J., Adhikari, R., Wei, J., Poveda, C., Keegan, B., Bailey, A. O., Chen, Y.-L., Gillespie, P. M., Kimata, J. T., Zhan, B., Hotez, P. J., Bottazzi, M. E.
10.1101/2021.08.24.457518 — Posted: 2021-08-25
Woodsmoke particulates alter expression of antiviral host response genes in human nasal epithelial cells infected with SARS-CoV-2 in a sex-dependent manner
Brocke, S. A., Billings, G. T., Taft-Benz, S. A., Alexis, N. E., Heise, M. T., Jaspers, I.
10.1101/2021.08.23.457411 — Posted: 2021-08-25
Direct RNA sequencing reveals SARS-CoV-2 m6A sites and possible differential DRACH motif methylation among variants
Campos, J. H., Maricato, J. T., Braconi, C. T., Antoneli, F., Janini, L. M. R., Briones, M. R.
10.1101/2021.08.24.457397 — Posted: 2021-08-25 Discussion: Onsite
Structure-based screening of drug candidates targeting the SARS-CoV-2 envelope protein
Xia, X., Zhang, Y., Li, S., Lin, H., Yan, Z.
10.1101/2021.08.25.457645 — Posted: 2021-08-25
Hydroxychloroquine for pre-exposure prophylaxis of COVID-19 in health care workers: a randomized, multicenter, placebo-controlled trial (HERO-HCQ)
Naggie, S., Milstone, A., Castro, M., Collins, S. P., Seetha, L., Anderson, D. J., Cahuayme-Zuniga, L., Batey-Turner, K., Cohen, L. W., Fraulo, E., Friedland, A., Garg, J., George, A., Mulder, H., Olson, R. E., O'Brien, E. C., Rothman, R. L., Shenkman, E., Shostak, J., Woods, C. W., Anstrom, K. J., Hernandez, A. F., HERO Research Program
10.1101/2021.08.19.21262275 — Posted: 2021-08-25
Discordant humoral and T cell immune responses to SARS-CoV-2 vaccination in people with multiple sclerosis on anti-CD20 therapy
Gadani, S. P., Reyes-Mantilla, M., Jank, L., Harris, S., Douglas, M., Smith, M. D., Calabresi, P. A., Mowry, E. M., Fitzgerald, K. C., Bhargava, P.
10.1101/2021.08.23.21262472 — Posted: 2021-08-25

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).