COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,082 Articles (22,658 medRxiv, 8,424 bioRxiv)

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A sarbecovirus found in Russian bats uses human ACE2
Seifert, S. N., Letko, M. C.
10.1101/2021.12.05.471310 — Posted: 2021-12-07
Receptor binding and escape from Beta antibody responses drive Omicron-B.1.1.529 evolution
Zahradnik, J., Tuekprakhon, A., Ginn, H. M., Duyvesteyn, H. M. E., Bahar, M., Khan, S., Avinoam, O., Zhou, D., Nutalai, R., Supasa, P., Wang, B., Dejnirattisai, W., Liu, C., Dijokaite, A., Temperton, N., Mongkolsapaya, J., Fry, E. E., Ren, J., Screaton, G. R., Schreiber, G., Stuart, D. I.
10.1101/2021.12.03.471045 — Posted: 2021-12-07
The Omicron Variant Increases the Interactions of SARS-CoV-2 Spike Glycoprotein with ACE2
Golcuk, M., Yildiz, A., Gur, M.
10.1101/2021.12.06.471377 — Posted: 2021-12-07
A zebrafish model of COVID-19-associated cytokine storm syndrome reveals differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.
Tyrkalska, S. D., Martinez-Lopez, A., Arroyo, A. B., Martinez-Morcillo, F. J., Candel, S., Mesa-del-Castillo, P., Garcia-Moreno, D., Cayuela, M. L., Mulero, V.
10.1101/2021.12.05.471277 — Posted: 2021-12-07
Constructing a multiple-layer interactome for SARS-CoV-2 in the context of lung disease: Linking the virus with human genes and co-infecting microbes
Lou, S., Li, T., Gerstein, M.
10.1101/2021.12.05.471290 — Posted: 2021-12-07
The High Transmission of SARS-CoV-2 Omicron (B.1.1.529) Variant is Not Only Due to Its hACE2 binding: A Free Energy of Perturbation Study
Fratev, F.
10.1101/2021.12.04.471246 — Posted: 2021-12-07
Omicron: A heavily mutated SARS-CoV-2 variant exhibits stronger binding to ACE2 and potently escape approved COVID-19 therapeutic antibodies
Woo, H. G., Shah, M.
10.1101/2021.12.04.471200 — Posted: 2021-12-07
The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: the case of the spike A222V mutation
Ginex, T., Marco-Marin, C., Wieczor, M., P. Mata, C., Krieger, J. M., Lopez-Redondo, M. L., Frances-Gomez, C., Ruiz-Rodriguez, P., Melero, R., Sanchez-Sorzano, C. O., Martinez, M., Gougeard, N., Forcada-Nadal, A., Zamora-Caballero, S., Gozalbo-Rovira, R., Sanz-Frasquet, C., Bravo, J., Rubio, V., Marina, A., The IBV-Covid19-Pipeline, , Geller, R., Comas, I., Gil, C., Coscolla, M., Orozco, M., Carazo, J.-M.
10.1101/2021.12.05.471263 — Posted: 2021-12-07
SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice
Tang, A., Buccholz, D. W., Szigety, K., Imbhiaka, B., Gao, S., Frankfurter, M., Wang, M., Yang, J., Hewins, P., Mericko-Ishizuka, P., Leu, N., Sterling, S., Monreal, I., Sahler, J., August, A., Zhu, X., Jurado, K., Xu, M., Morrisey, E., Millar, S., Aguilar-Carreno, H., Kahn, M.
10.1101/2021.12.04.471245 — Posted: 2021-12-07
A nonrandomized phase 2 trial of oral thymic peptides in hospitalized patients with Covid-19
Ramos-Zaldivar, H. M., Reyes-Perdomo, K. G., Espinoza-Moreno, N. A., Dox-Cruz, E. T., Aguirre Urbina, T. C., Rivera Caballero, A. Y., Perdomo Dominguez, E. S., Pena Calix, S. G., Monterroso-Reyes, J. M., Caballero Vásquez, E. F., Zelaya Ortiz, T. S., Rodriguez-Machado, H. E., Forgas Solis, M. A., Sebilla Silva, I., Zavala Galeano, M. E., Morga Alvarado, A. A., Solis Medina, A. M. N., Guerrero-Diaz, L. M., Jimenez-Faraj, J. E., Perello Santos, C. A., Moncada Arita, W. A., Valdiviezo Montufar, D. F., Hernandez Sabillon, J. D., Sorto G., M. L., Padilla Navarro, X. X., Palomo-Bermudez, V. A.
10.1101/2021.12.05.21267318 — Posted: 2021-12-07

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).