COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,241 Articles (22,733 medRxiv, 8,508 bioRxiv)

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Safety and immunogenicity of a heterologous boost with a recombinant vaccine, NVSI-06-07, in the inactivated vaccine recipients from UAE: a phase 2 randomised, double-blinded, controlled clinical trial
AlKaabi, N., Yang, Y. K., Zhang, J., Xu, K., Liang, Y., Kang, Y., Su, J. G., Yang, T., Hussein, S., ElDein, M. S., Shao, S., Yang, S. S., Lei, W., Gao, X. J., Jiang, Z., Wang, H., Li, M., Mekki, H. M., Zaher, W., Mahmoud, S., Zhang, X., Qu, C., Liu, D. Y., Zhang, J., Yang, M., ElTantawy, I., Xiao, P., Wang, Z. N., Yin, J. L., Mao, X. Y., Zhang, J., Liu, N., Shen, F. J., Qu, L., Zhang, Y. T., Yang, X. M., Wu, G., Li, Q. M.
10.1101/2021.12.29.21268499 — Posted: 2022-01-04
Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern.
Valanparambil, R., Carlisle, J., Ahmed, R., Linderman, S., Akthar, A., Millett, R. L., Lai, L., Chang, A., McCook, A., Switchenko, J., Nasti, T., Saini, M., Andreas Wieland, A. W., Manning, K., Ellis, M., Moore, K., Foster, S., Floyd, K., Davis-Gardner, M., Viswanadh Edara, V., Patel, M., Steur, C., Nooka, A., Green, F., Johns, M., O Brein, F., Shanmugasundaram, U., Zarnitsyna, V., Ahmed, H., Nyhoff, L., Mantus, G., Garett, M., Edupuganti, S., Behra, M., Antia, R., Wrammert, J., Suthar, M., Dhodapkar, M., Ramalingam, S.
10.1101/2022.01.03.22268599 — Posted: 2022-01-03
Shielding individuals at high risk of COVID-19: a micro-simulation study
van Zandvoort, K., Favas, C., Checchi, F.
10.1101/2022.01.03.22268675 — Posted: 2022-01-03
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism
Willett, B. J., Grove, J., MacLean, O., Wilkie, C., Logan, N., De Lorenzo, G., Furnon, W., Scott, S., Manali, M., Szemiel, A., Ashraf, S., Vink, E., Harvey, W., Davis, C., Orton, R., Hughes, J., Holland, P., Silva, S. V., Pascall, D., Puxty, K., da Silva Filipe, A., Yebra, G., Shaaban, S., Holden, M. T. G., Pinto, R. M., Gunson, R., Templeton, K., Murcia, P., Patel, A., The COVID-19 DeplOyed VaccinE (DOVE) Investigators, , COVID-19 EVADE Cohort Study, , The COVID-19 Genomics UK (COG-UK) Consortium, , The G2P-UK National Virology Consortium, , Haughney, J., Robertson, D. L., Palmarini, M., Ray, S., Thomson, E. C.
10.1101/2022.01.03.21268111 — Posted: 2022-01-03 Discussion: Onsite | Offsite
Mapping the antigenic diversification of SARS-CoV-2
van der Straten, K., Guerra, D., van Gils, M., Bontjer, I., Caniels, T. G., van Willigen, H. D., Wynberg, E., Poniman, M., Burger, J. A., Bouhuijs, J. H., Lavell, A., Appelman, B., Sikkens, J. J., Bomers, M., Han, A. X., Nichols, B. E., Prins, M., Vennema, H., Reusken, C., Eggink, D., de Jong, M., de Bree, G. J., Russell, C. A., Sanders, R. W.
10.1101/2022.01.03.21268582 — Posted: 2022-01-03
Melatonin drugs inhibit SARS-CoV-2 entry into the brain and virus-induced damage of cerebral small vessels
Cecon, E., Fernandois, D., Renault, N., Coelho, C. F. F., Wenzel, J., Bedart, C., Izabelle, C., Gallet, S., Le Poder, S., Klonjkowski, B., Schwaninger, M., PREVOT, V., Dam, J., Jockers, R.
10.1101/2021.12.30.474561 — Posted: 2022-01-03
Integrated Autolysis, DNA Hydrolysis and Precipitation Enables an Improved Bioprocess for Q-Griffithsin, a Broad-Spectrum Antiviral and Clinical-Stage anti-COVID-19 Candidate
Decker, J. S., Menacho-Melgar, R., Lynch, M. D.
10.1101/2021.12.30.474602 — Posted: 2022-01-03
Hydrodynamics of spike proteins dictate a transport-affinity competition for SARS-CoV-2 and other enveloped viruses
Moreno, N., Moreno-Chaparro, D., Balboa Usabiaga, F., Ellero, M.
10.1101/2022.01.03.474721 — Posted: 2022-01-03
Cell culture model system utilizing engineered A549 cells to express high levels of ACE2 and TMPRSS2 for investigating SARS-CoV-2 infection and antivirals
Chang, C.-W., Parsi, K. M., Somasundaran, M., Vanderleeden, E., Cruz, J., Cousineau, A., Liu, P., Li, Q., Wang, Y., Maehr, R., Wang, J. P., Finberg, R. W.
10.1101/2021.12.31.474593 — Posted: 2022-01-03
A dual-receptor mechanism between integrins and ACE2 widens SARS-CoV-2 tissue tropism
Nader, D., Gressett, T. E., Hossen, M. L., Chapagain, P. P., Kerrigan, S. W., Bix, G.
10.1101/2022.01.02.474028 — Posted: 2022-01-03 Discussion: Onsite

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).