Channel:  Harvard Program in Therapeutic Sciences

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

103 Articles

FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining
Bachman, J. A., Gyori, B. M., Sorger, P.
10.1101/225698 — Posted: 2018-03-26
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
Lin, J.-R., Izar, B., Mei, S., Wang, S., Shah, P., Yapp, C., Santagata, S., Sorger, P.
10.1101/151738 — Posted: 2018-05-10
Machine characterization of rat toxin responses identifies disease states, tolerance mechanisms and organ to whole-body communication
Shimada, K., Mitchison, T.
10.1101/322446 — Posted: 2018-05-28
Cheminformatics tools for analyzing and designing optimized small molecule libraries
Moret, N., Clark, N., Hafner, M., Wang, Y., Lounkine, E., Medvedovic, M., Wang, J., Gray, N., Jenkins, J., Sorger, P.
10.1101/358978 — Posted: 2018-06-29
pNeRF: Parallelized Conversion from Internal to Cartesian Coordinates
AlQuraishi, M.
10.1101/385450 — Posted: 2018-08-06
End-to-end differentiable learning of protein structure
AlQuraishi, M.
10.1101/265231 — Posted: 2018-08-29
A multi-center study on factors influencing the reproducibility of in vitro drug-response studies
Niepel, M., Hafner, M., Mills, C., Subramanian, K., Williams, E. H., Chung, M., Gaudio, B., Barrette, A. M., Stern, A. D., Hu, B., Korkola, J. E., LINCS Consortium, , Gray, J. W., Birtwistle, M. R., Heiser, L. M., Sorger, P. K.
10.1101/213553 — Posted: 2019-02-05
Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming
Wang, H., Sheehan, R. P., Palmer, A. C., Everley, R. A., Boswell, S. A., Ron-Harel, N., Ringel, A. E., Holton, K. M., Jacobson, C. A., Erickson, A. R., Maliszewski, L., Haigis, M. C., Sorger, P. K.
10.1101/365841 — Posted: 2019-03-12
Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity
Hafner, M., Mills, C. E., Subramanian, K., Chen, C., Chung, M., Boswell, S. A., Everley, R. A., Liu, C., Walmsley, C. S., Juric, D., Sorger, P.
10.1101/211680 — Posted: 2019-03-19
Combined inhibition of mTOR and PIKKs exploits replicative and checkpoint vulnerabilities to induce death of PI3K-activated triple-negative breast cancer cells
Chopra, S. S., Jenney, A., Palmer, A., Niepel, M., Chung, M., Mills, C., Sivakumaren, S. C., Liu, Q., Chen, J.-Y., Yapp, C., Asara, J., Gray, N. S., Sorger, P. K.
10.1101/700625 — Posted: 2019-07-12

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