Channel: University of Chicago

This collection includes bioRxiv and medRxiv papers from authors at University of Chicago.

2851 Articles

MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity

Pottorf, T. S., Fagan, M., Burkey, B., Cho, D. J., Vath, J. E., Tran, P. V.

10.1101/800151 — Posted: 2019-10-13

Genome-wide associations reveal human-mouse genetic convergence and modifiers of myogenesis, CPNE1 and STC2

Hernandez Cordero, A. I., Gonzales, N. M., Parker, C. C., Sokoloff, G., Vandenbergh, D. J., Cheng, R., Abney, M., Skol, A., Douglas, A., Palmer, A. A., Gregory, J. S., Lionikas, A.

10.1101/370312 — Posted: 2019-10-10

Relaxed constraint and functional divergence of the progesterone receptor (PGR) in the human stem-lineage

Marinic, M., Lynch, V. J.

10.1101/799569 — Posted: 2019-10-09

Determinants of telomere length across human tissues

Demanelis, K., Jasmine, F., Chen, L. S., Chernoff, M., Tong, L., Shinkle, J., Sabarinathan, M., Lin, H., Ramirez, E., Oliva, M., Kim-Hellmuth, S., Stranger, B. E., Ardlie, K. G., Aguet, F., Ahsan, H., GTEx Consortium, , Doherty, J., Kibriya, M. G., Pierce, B. L.

10.1101/793406 — Posted: 2019-10-07

Mechanisms of tissue-specific genetic regulation revealed by latent factors across eQTLs

He, Y., Chhetri, S. B., Arvanitis, M., Srinivasan, K., Aguet, F., Ardlie, K. G., Barbeira, A. N., Bonazzola, R., Im, H. K., GTEx Consortium, , Brown, C. D., Battle, A.

10.1101/785584 — Posted: 2019-10-06

Membrane stiffness is a key determinant of E coli MscS channel mechanosensitivity

Xue, F., Cox, C. D., Bavi, N., Rohde, P. R., Nakayama, Y., Martinac, B.

10.1101/790501 — Posted: 2019-10-04

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Zhang, H., Ahearn, T., Lecarpentier, J., Barnes, D., Beesley, J., Qi, G., Jiang, X., O'Mara, T. A., Zhao, N., Bolla, M. K., Dunning, A. M., Dennis, J., Wang, Q., Abu Ful, Z., Aittomaki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Arun, B. K., Auer, P. L., Azzollini, J., Barrowdale, D., Becher, H., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bialkowska, K., Blanco, A., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Bondavalli, D., Borg, A., Brauch, H., Brenner, H., Briceno, I., Broeks, A., Brucker, S. Y., Bruning, T., Burwinkel, B., Buys, S.

10.1101/778605 — Posted: 2019-10-04

Long non-coding RNA gene regulation and trait associations across human tissues

de Goede, O. M., Ferraro, N. M., Nachun, D. C., Rao, A., Aguet, F., Barbeira, A. N., Castel, S. E., Kim-Hellmuth, S., Park, Y., Scott, A. J., Strober, B. J., GTEx Consortium, , Brown, C. D., Wen, X., Hall, I. M., Battle, A., Lappalainen, T., Im, H. K., Ardlie, K. G., Quertermous, T., Kirkegaard, K., Montgomery, S. B.

10.1101/793091 — Posted: 2019-10-04

Diverse transcriptomic signatures across human tissues identify functional rare genetic variation

Ferraro, N. M., Strober, B. J., Einson, J., Li, X., Aguet, F., Barbeira, A. N., Castel, S. E., Davis, J. R., Hilliard, A. T., Kotis, B., Park, Y., Scott, A. J., Smail, C., Tsang, E. K., Ardlie, K. G., Assimes, T. L., Hall, I., Im, H. K., GTEx Consortium, , Lappalainen, T., Mohammadi, P., Montgomery, S. B., Battle, A.

10.1101/786053 — Posted: 2019-10-03

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Aguet, F., Barbeira, A. N., Bonazzola, R., Brown, A., Castel, S. E., Jo, B., Kasela, S., Kim-Hellmuth, S., Liang, Y., Oliva, M., Parsana, P. E., Flynn, E., Fresard, L., Gaamzon, E. R., Hamel, A. R., He, Y., Hormozdiari, F., Mohammadi, P., Munoz-Aguirre, M., Park, Y., Saha, A., Segrc, A. V., Strober, B. J., Wen, X., Wucher, V., Das, S., Garrido-Martin, D., Gay, N. R., Handsaker, R. E., Hoffman, P. J., Kashin, S., Kwong, A., Li, X., MacArthur, D., Rouhana, J. M., Stephens, M., Todres, E., Vinuela, A., Wang, G., Zou, Y., The GTEx Consortium, , Brown, C. D., Cox, N., Dermitzakis, E., Engelhardt

10.1101/787903 — Posted: 2019-10-03

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