Channel: Cold Spring Harbor Laboratory

This collection includes bioRxiv and medRxiv papers from authors at Cold Spring Harbor Laboratory.

683 Articles

Small molecule modulators of TOX protein re-invigorate T cell activity

Wu, B., Chang, H. J., Singh, P., Hostetler, A., Xiang, Y., Guo, S., Wang, F. Y., Zhong, J. J., Leifer, B. S., Schiavoni, R. P., Jiang, N., Choudhary, A., Westcott, P. M. K., Koehler, A. N.

10.1101/2025.03.03.641115 — Posted: 2025-06-18

Oncogenic and tumor-suppressive forces converge on a progenitor-orchestrated niche to shape early tumorigenesis

Reyes, J., Del Priore, I., Chaikovsky, A. C., Pasnuri, N., Elhossiny, A. M., Krause, T., Moorman, A., Snopkowski, C., Takizawa, M., Burdziak, C., Ratnayeke, N., Masillioni, I., Ho, Y.-J., Chaligne, R., Romesser, P. B., Filliol, A., Nawy, T., Morris, J. P., Zhao, Z., Di Magliano, M. P., Alonso-Curbelo, D., Pe'er, D., Lowe, S. W.

10.1101/2025.06.10.656791 — Posted: 2025-06-12

Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis

Gazzara, E., Adrover, J. M., Lui, A., Han, S., Aminzada, Z., Bhandari, N., Sivetz, N., Shirue, V. S., Shergill, B. S., Curtis, M. B., George, S. C., Cicala, A., Rishi, A., Chung, C., Devoe, C., Huang, H., Weiss, M., Lou, E., Tuveson, D. A., Beyaz, S., Westcott, P. M. K., Egeblad, M., Gholami, S.

10.1101/2025.05.30.657122 — Posted: 2025-06-07

Crosslinked CXCR4 Signals Decreased Motility and Increased Adhesion of T Cells

Pearson, J., Yang, J.-I., Krivitsky, S., Kelley, Z., Fearon, D. T.

10.1101/2025.06.04.652236 — Posted: 2025-06-05

Sustained Glucose Turnover Flux Distinguishes Cancer Cachexia from Nutrient Limitation

Kwon, Y. Y., Liang, Y., Gomez-Jenkins, M., Ahmed, M., Jiang, G., Hsiang, J., Lewis, D., Janowitz, T., Goncalves, M. D., White, E., Hui, S.

10.1101/2025.05.15.654370 — Posted: 2025-05-20

Skeletonization of neuronal processes using Discrete Morse techniques from computational topology

Banerjee, S., Stam, C., Tward, D. J., Savoia, S., Wang, Y., Mitra, P. P.

10.1101/2025.05.12.653477 — Posted: 2025-05-15

Effect of plant tissue culture parameters on the ploidy level of Physalis grisea, Solanum lycopersicum, and Solanum prinophyllum regenerants

Van Eck, J., Swartwood, K., Green, Y., Gentile, I., Lippman, Z. B.

10.1101/2025.05.01.651681 — Posted: 2025-05-03

3D multimodal histological atlas and coordinate framework for the mouse brain and head

Tward, D. J., Flannery, P. J., Savoia, S., Mezias, C., Banerjee, S., Richman, M., Lodato, B., O'Rourke, J. R., Balani, S., Arima, K., Washington, S., Coronado-Leija, R., Zhang, J., Mitra, P. P.

10.1101/2025.04.30.650246 — Posted: 2025-05-01

On learning functions over biological sequence space: relating Gaussian process priors, regularization, and gauge fixing

Petti, S., Marti-Gomez, C., Kinney, J. B., Zhou, J., McCandlish, D. M.

10.1101/2025.04.26.650699 — Posted: 2025-04-30

Parametric modulation of a shared midbrain circuit drives distinct vocal modes in a singing mouse

Zheng, X. M., Harpole, C. E., Davis, M. B., Banerjee, A.

10.1101/2025.04.04.647309 — Posted: 2025-04-27

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