Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1070 Articles

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction

Hoffmann, T. J., Graff, R. E., Madduri, R. K., Rodriguez, A. A., Cario, C. L., Feng, K., Jiang, Y., Wang, A., Klein, R. J., Pierce, B. L., Eggener, S., Tong, L., Blot, W., Long, J., Goss, L. B., Darst, B. F., Rebbeck, T., Lachance, J., Andrews, C., Adebiyi, A. O., Adusei, B., Aisuodionoe-Shadrach, O. I., Fernandez, P. W., Jalloh, M., Janivara, R., Chen, W. C., Mensah, J. E., Agalliu, I., Berndt, S. I., Shelley, J. P., Schaffer, K., Machiela, M. J., Freedman, N. D., Huang, W.-Y., Li, S. A., Goodman, P. J., Till, C., Thompson, I., Lilja, H., Ranatunga, D. K., Presti, J., Van Den Eeden, S. K., Ch

10.1101/2023.10.27.23297676 — Posted: 2024-08-20

KMT2A oncoproteins induce epigenetic resistance to targeted therapies

Janssens, D. H., Duran, M., Otto, D. J., Wu, W., Xu, Y., Kirkey, D., Mullighan, C. G., Yi, J. S., Meshinchi, S., Sarthy, J. F., Ahmad, K., Henikoff, S.

10.1101/2023.12.29.573681 — Posted: 2024-08-12

Low-Cost Robotic Manipulation of Live Microtissues for Cancer Drug Testing

Stepanov, I., Gottshall, N. R., Ahmadianyazdi, A., Sinha, D., Lockhart, E., Nguyen, T. N., Hassan, S., Horowitz, L., Yeung, R., Gujral, T. S., Folch, A.

10.1101/2024.03.21.586169 — Posted: 2024-08-06

A targeted CRISPR screen identifies ETS1 as a regulator of HIV latency.

Ashokkumar, M., Hafer, T. L., Felton, A., Archin, N., Margolis, D. M., Emerman, M., Browne, E. P.

10.1101/2024.08.03.606477 — Posted: 2024-08-03

Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

Nugent, P. J., Park, H., Wladyka, C. L., Chen, K. Y., Bynum, C., Quarterman, G., Hsieh, A. C., Subramaniam, A. R.

10.1101/2024.07.25.605204 — Posted: 2024-07-26

The battle of the sexes in humans is highly polygenic

Cole, J. M., Scott, C. B., Johnson, M. M., Golightly, P. R., Carlson, J., Ming, M. J., Harpak, A., Kirkpatrick, M.

10.1101/2024.07.23.604850 — Posted: 2024-07-24

Stable centromere association of the yeast histone variant Cse4 requires its essential N-terminal domain

Popchock, A. R., Hedouin, S., Mao, Y., Asbury, C. L., Stergachis, A. B., Biggins, S.

10.1101/2024.07.24.604937 — Posted: 2024-07-24

Prevalent fast evolution of genes involved in heterochromatin functions

Lin, L., Huang, Y., McIntyre, J., Chang, C.-H., Colmenares, S. S., Lee, G. Y. C.

10.1101/2024.03.03.583199 — Posted: 2024-07-23

Genetic variants affect diurnal glucose levels throughout the day

Sinnott-Armstrong, N., Strausz, S., Urpa, L., Abner, E., Valliere, J., Estonian Biobank Research Team, , Palta, P., Dashti, H. S., Daly, M., Pritchard, J. K., Saxena, R., Jones, S. E., Ollila, H. M.

10.1101/2024.07.22.604631 — Posted: 2024-07-23

Oxygen is Toxic in the Cold in C. elegans.

Suraci, C. M., Morrison, M. L., Roth, M. B.

10.1101/2024.07.17.603990 — Posted: 2024-07-22

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