Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1070 Articles

Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy

Lichauco, C., Foss, E. J., Gatbonton-Schwager, T., Athow, N. F., Lofts, B., Acob, R., Taylor, E., Marquez, J. J., Lao, U., Miles, s., Bedalov, A.

10.1101/2024.03.21.586113 — Posted: 2024-10-28

An integrated view of the structure and function of the human 4D nucleome

The 4D Nucleome Consortium, , Dekker, J., Oksuz, B. A., Zhang, Y., Wang, Y., Minsk, M. K., Kuang, S., Yang, L., Gibcus, J. H., Krietenstein, N., Rando, O., Xu, J., Janssens, D. H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A. S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S. A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S. V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C. J., Szczepinska

10.1101/2024.09.17.613111 — Posted: 2024-10-27

Predicting the 10-year risk of cardiomyopathy in long-term survivors of childhood cancer: a report from the St. Jude Lifetime Cohort and the Childhood Cancer Survivor Study

Petrykey, K., Chen, Y., Neupane, A., French, J., Wang, H., Xiang, H., Dixon, S. B., Vukadinovich, C., Im, C., Ehrhardt, M. J., Mulrooney, D. A., Sharafeldin, N., Wang, X., Howell, R. M., Jefferies, J. L., Burridge, P. W., Oeffinger, K. C., Gramatges, M. M., Bhatia, S., Robison, L. L., Ness, K. K., Hudson, M. M., Chow, E. J., Armstrong, G. T., Yasui, Y., Sapkota, Y.

10.1101/2024.10.24.24316064 — Posted: 2024-10-25

Assessing how women access healthcare to inform cervical cancer and HIV screening in rural Uganda.

Sheehan, M., Dau, H., AboMoslim, M., Naguti, P., Mwandacha, N., Booth, A., Ruck, C., Smith, L., Orem, J., Ogilvie, G., Nakisige, C.

10.1101/2024.10.22.24315934 — Posted: 2024-10-23

Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma

Arora, S., Holland, E., Vardharajan, S., Taylor, M., Sahm, F., Mack, S. C., Sievers, P., Korshunov, A., Nuechterlein, N., Jensen, M., Glatzer, G.

10.1101/2024.10.21.619495 — Posted: 2024-10-22

Protein catabolites as blood-based biomarkers of aging physiology: Findings from the Dog Aging Project

Harrison, B. R., Partida-Aguilar, M., Marye, A., Djukovic, D., Kauffman, M., Dunbar, M. D., Mariner, B. L., McCoy, B. M., Algavi, Y. M., Muller, E., Baum, S., Bamberger, T., Raftery, D., Creevy, K. E., Dog Aging Project Consortium, , Avery, A., Borenstein, E., Snyder-Mackler, N., Promislow, D. E.

10.1101/2024.10.17.618956 — Posted: 2024-10-21

Statistical analysis of repertoire data demonstrates the influence of microhomology in V(D)J recombination

Russell, M. L., Trofimov, A., Bradley, P., Matsen, F. A.

10.1101/2024.10.16.618753 — Posted: 2024-10-18

Sugar-rich foods exacerbate antibiotic-induced microbiome injury

Dai, A., Adintori, P. A., Funnell, T., Jogia, W. P., Fei, T., Waters, N. R., Rangesa, M., Ballweg, A., Gipson, B., Raj, S., Hayase, E., Markey, K. A., Burgos da Silva, M., Miltiadous, O., Brambilla, C. Z., Buchan, M. L., Peets, T., Gradissimo, A., Smith, N., Katsamakis, Z., Warren, A., Amoretti, L. A., Duan, C., Zhang, C., Matheis, F., Sullivan, A. P., Slingerland, J. B., Clurman, A., Brereton, D. G., Giardina, P. A., Gomes, A. L. C., Johnson, A. J., Knights, D., Jenq, R. R., Perales, M.-A., Giralt, S. A., Schluter, J., van den Brink, M. R. M., Peled, J.

10.1101/2024.10.14.617881 — Posted: 2024-10-17

A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV

Sajadi, M., Abbasi, A., Rikhtegaran Tehrani, Z., Siska, C., Clark, R., Chi, W., Seaman, M. S., Mielke, D., Wagh, K., Liu, Q., Jumpa, T., Ketchem, R. R., Nguyen, D. N., Tolbert, W. D., Pierce, B. G., Atkinson, B., Deming, D., Sprague, M., Asakawa, A., Ferrer, D., Dunn, Y., Calvillo, S., Yin, R., Guest, J. D., Korber, B., Mayer, B. T., Sato, A. H., Ouyang, X., Foulke, S., Habibzadeh, P., Karimi, M., Aslanabadi, A., Hojabri, M., Saadat, S., Zareidoodeji, R., Kedzior, M., Pozharski, E., Heredia, A., Montefiori, D., Ferrari, G., Pazgier, M., Lewis, G. K., Jardine, J. G., Lusso, P., Devico, A.

10.1101/2024.10.14.618178 — Posted: 2024-10-17

Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites

Lawore, D. C., Jena, S., Berard, A. R., Birse, K., Lamont, A., Mackelprang, R. D., Noel-Romas, L., Perner, M., Hou, X., Irungu, E., Mugo, N., Knodel, S., Muwonge, T. R., Katabira, E., Hughes, S. M., Levy, C., Calienes, F. L., Hladik, F., Lingappa, J. R., Burgener, A. D., Green, L. N., Brubaker, D. K.

10.1101/2024.10.10.616351 — Posted: 2024-10-17

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