Channel: Fred Hutchinson Cancer Center

This collection includes bioRxiv and medRxiv papers from authors at Fred Hutchinson Cancer Center.

1398 Articles

Aclarubicin disrupts RNA polymerase II progression at replication-coupled histone genes

Nguyen, K. K., Wooten, M., Ahmad, K., Henikoff, S.

10.64898/2026.07.08.737292 — Posted: 2026-07-09

Adaptive plasticity of aspartate metabolism in succinate dehydrogenase-deficient cancer cells

Sokolov, D., Zheng, E., Danquah, S., Hart, M. L., Sullivan, L. B.

10.64898/2026.05.18.726122 — Posted: 2026-07-08

Regulatory T cells restrain cytotoxic and bystander CD8 T cells without compromising antigen-driven memory in mucosal tissue

Cruz Talavera, I., Graham, J. B., Swarts, J. L., Traxinger, B. R., Peters, M. Q., Warrier, L., Koehne, A. L., Arkatkar, T., Jerome, K. R., Prlic, M., Lund, J. M.

10.64898/2026.02.25.708034 — Posted: 2026-07-08

Differential response to LSD1 inhibition in prostate cancer reveals a YAP1 vulnerability in the neuroendocrine subtype

Jasim, S., Kumar, R., Kim, S., Krueger, T., Coleman, I., Dalrymple, S., Antony, L., Rosen, D., Hanratty, B., Patel, R., Nelson, P., Aghaei, Z., Beumer, J., Haffner, M., Lotan, T., Mandl, A., Carducci, M., Kachhap, S., Isaacs, J., Denmeade, S., Rienhoff, H., Sena, L., Brennen, W.

10.1101/2024.01.17.576106 — Posted: 2026-07-08

An interdependent Cbf1-CCAN interaction stabilizes the budding yeast kinetochore

Hedouin, S., Hu, C., Biggins, S.

10.64898/2026.03.25.714319 — Posted: 2026-07-08

Cysteine-mediated bortezomib resistance is governed by α-ketoacid availability

Brain, J. A., Chang, S. M., Kobiesa, M., Rector, L. G., Ceribelli, M., Kim, S. H., Li, Z., Do, B. T., Che, K. J., Holland, D. T., Block, S., Chang, R., Oaks, G. E., Thomas, C. J., Vander Heiden, M. G., Sullivan, L. B.

10.64898/2026.07.06.736827 — Posted: 2026-07-07

Fitness flux in SARS-CoV-2 and influenza H3N2

Bedford, T.

10.64898/2026.07.05.736619 — Posted: 2026-07-06

Complex structural variation, phylogeny, and disease associations of the mucin pangenome

Plender, E. G., Prodanov, T., Lin, J., Wong, I., Wertz, J., Gordon, W. W., Bamshad, M. J., Munson, K. M., O'Neal, W. K., Bloom, J. D., Human Pangenome Reference Consortium, , Marschall, T., Eichler, E. E.

10.64898/2026.07.01.26356476 — Posted: 2026-07-04

Priming of Multiple HIV Neutralizing B Cell Precursors in Humans

Yeh, C.-H., Walsh, S. R., Parsons, R. J., Zhang, Q. E., Thakur, B., Song, K., Liu, K., Kirshner, H. F., Van ltallie, E., Clark, M., Hahn, W. O., Song, S., Lin, L., Huang, H.-I., Lugo, J., Quan, A., Xue, Y., chen, Y., Ryan, T., Mansouri, K., Spence, T. N., Laukaitis, H. A., Parks, R., Barr, M., Schweer, E., Levering, N., Eaton, A., Shen, S., Janowska, K., Ilevbare, V., Johnson, G., Wang, P., Cain, D. W., Arus-Altuz, A., Donahue, E., Zhbannikov, I., Berry, M., Venkatayogi, S., Martin Beem, J. S., Hyrien, O., Yu, P.-C., Polakowski, L. L., Tindale, I., Yurdadon, C., Burnham, R., Andriesen, J., Wag

10.64898/2026.05.02.26352058 — Posted: 2026-06-30

Effectiveness of pharmacy-based HIV pre- and post-exposure prophylaxis delivery: a cluster-randomized trial in Kenya

Ortblad, K. F., Meisner, A., Omollo, V., Kareithi, T., Roche, S. D., Ongwen, P., Asewe, M., Anyona, M. O., Banerjee, P., Curran, K., Gichuru, E., Harkey, K., Juma, L., Kiptinness, C., Malen, R. C., Mugambi, M. L., Otieno, P., Pintye, J., Rono, B., Schaafsma, T. T., Shah, P. D., Sharma, M., Thomas, K. K., Yu, K., Were, D., Bukusi, E. A., Ngure, K.

10.64898/2026.06.26.26356703 — Posted: 2026-06-29

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