Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2109 Articles

Disentangling folding from energetic traps in simulations of disordered proteins

Lotthammer, J. M., Holehouse, A. S.

10.1101/2024.11.06.622270 — Posted: 2024-11-08

DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides

Ren, Q., Wang, J., Idikuda, V., Zhang, S., Shin, J., Ludlam, W. G., Real Hernandez, L. M., Levental, I., Martemyanov, K., Chanda, B., Bao, H.

10.1101/2024.11.07.622281 — Posted: 2024-11-08

Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

Chen, Y., Lee, J. H. H., Li, J., Park, S., Perez-Flores, M. C., Peguero, B., Kersigo, J., Kang, M., Choi, J., Levine, L., Gratton, M. A., Friztsch, B., Yamoah, E. N.

10.1101/2023.10.08.561387 — Posted: 2024-11-08

A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework

Quah, S. K. L., Jo, B., Geniesse, C., Uddin, L. Q., Mumford, J. A., Barch, D. M., Fair, D. A., Gotlib, I. H., Poldrack, R. A., Saggar, M.

10.1101/2024.01.31.577486 — Posted: 2024-11-08

Metapredict enables accurate disorder prediction across the Tree of Life

Lotthammer, J. M., Hernandez-Garcia, J., Griffith, D., Weijers, D., Holehouse, A. S., Emenecker, R. J.

10.1101/2024.11.05.622168 — Posted: 2024-11-07

Transdiagnostic alterations in white matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium

Velzen, L. S. v., Colic, L., Ceja, Z., Dauvermann, M. R., Villa, L. M., Savage, H. S., Toenders, Y. J., Dehestani, N., Zhu, A. H., Campos, A. I., Salminen, L. E., Agartz, I., Alexander, N., Ayesa-Arriola, R., Ballard, E. D., Banaj, N., Barkhau, C., Bagoze, Z., Bauer, J., Benedetti, F., Berger, K., Besteher, B., Brosch, K., Canal-Rivero, M., Cervenka, S., Colle, R., Connolly, C. G., Corruble, E., Courtet, P., Couvy-Duchesne, B., Crespo-Facorro, B., Cullen, K. R., Dannlowski, U., Deverdun, J., Diaz-Zuluaga, A. M., Dietze, L. M. F., Evans, J. W., Fani, N., Flinkenflgel, K., Friedman, N. P., Gotli

10.1101/2024.11.07.24316876 — Posted: 2024-11-07

BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

Chen, B., Stark, D. C., Jadhav, P. V., Lynn-Nguyen, T. M., Halligan, B. S., Rossiter, N. J., Sindoni, N., Shin, M., Paulo, J. A., Chang, M., Koo, I., Koshkin, S., Eyunni, S., Ronchi, P., Paulsen, M. T., Morlacchi, P., Hanna, D. A., Lin, J., Guerra, R. M., Pagliarini, D., Banerjee, R., Parolia, A., Ljungman, M., Patterson, A. D., Mancias, J. D., Mosalaganti, S., Sexton, J., Cali, T., Lyssiotis, C. A., Shah, Y. M.

10.1101/2024.02.02.578646 — Posted: 2024-11-05

Development and validation of the Immune Profile Score (IPS), a novel multi-omic algorithmic assay for stratifying outcomes in a real-world cohort of advanced solid cancer patients treated with immune checkpoint inhibitors

Zander, A., Erbe, R., Liu, Y., Jin, A., Hyun, S. W., Mukhopadhyay, S., Terdich, B., Rosasco, M., Patel, N., Mahon, B., Sasser, K., Ting-Lin, M., Nimeiri, H., Guinney, J., Adkins, D. R., Zibelman, M., Beauchamp, K. A., Sangli, C., Stein, M. M., Taxter, T., Chan, T. A., Patel, S. P., Cohen, E.

10.1101/2024.11.05.24316583 — Posted: 2024-11-05

Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection

Alcorn, M. D. H., Sun, C., Gilliland, T. C., Lukash, T., Crasto, C. M., Raju, S., Diamond, M., Weaver, S., Klimstra, W. B.

10.1101/2024.11.04.621500 — Posted: 2024-11-04

Transcriptome-wide association study of Alzheimer disease reveals many differentially expressed genes and multiple biological pathways in brain tissue from African American donors

Logue, M., Labadorf, A., O'Niell, N. K., Dickson, D. W., Dugger, B. N., Flanagan, M. E., Frosch, M. P., Gearing, M., Jin, L.-W., Kofler, J., Mayeux, R., McKee, A., Miller, C. A., Murray, M. E., Nelson, P. T., Perrin, R. J. E., Schneider, J. A., Stein, T. D., Teich, A., Tronsco, J. C., Wang, S.-H., Wolozin, B., Mez, J., Farrer, L. A.

10.1101/2024.10.29.24316311 — Posted: 2024-11-04

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