Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2955 Articles

Electron microscopy visualization of cell-free mitochondrial DNA-containing extracellular vesicles in human plasma, serum, and saliva

Volos, A., Franklin, S. G., Michelson, J., Rausser, S., Brestoff, J. R., Picard, M.

10.1101/2025.10.15.25338094 — Posted: 2026-04-28

Paired CRISPR screens identify mitochondrial metabolism and UBE2H as aneuploid-specific dependencies in human cancer cell lines

Schukken, K. M., Akalu, S. M., Zou, C., Kandikuppa, P. K., Hagenson, R. A., Keane, J. L., Lynch, M. P., Yoshimoto, T., Klingbeil, O., Sausville, E. L., Mishra, S., Vakoc, C. M., Storchova, Z., Aitken, S. J., Sheltzer, J. M.

10.64898/2026.04.26.720636 — Posted: 2026-04-28

SurvTEDVAE: A Disentangled Variational Autoencoder for Heterogeneous Treatment Effect Estimation with Time-to-Event Outcomes

Powell, W. J. B., Zhang, L.

10.64898/2026.04.26.26351790 — Posted: 2026-04-28

Genetics of cannabis ever-use and frequency across ancestries implicate novel loci and brain-specific biology

Pasman, J. A., Gerring, Z. F., Thorp, J. G., Abdellaoui, A., Youssef, P., Ori, A., Smadi, M., Thijssen, A. B., Woodward, D., Wormington, B., Adkins, D. E., Aliev, F., Aliev, F., Chatzinakos, C., Elson, S. L., Fontanillas, P., Gizer, I. R., Gu, H., Hines, L. A., Johnson, E. C., Koiv, K., Lind, P. A., Lind, P. A., Lind, P. A., Mosing, M. A., Nolte, I. M., Ong, J.-S., Otto, J. M., Palviainen, T., Peterson, R. E., Sallis, H. M., Shabalin, A. A., Shabalin, A. A., Shin, J., Thomas, N. S., Thomas, N. S., van der Laan, C. M., van der Most, P. J., van Dorsselaer, S., van Eijk, K. R., Wootton, R. E., Wo

10.64898/2026.04.25.26351611 — Posted: 2026-04-27

Integrative Clinical-Molecular Modeling Identifies LRRN4CL as a Determinant of Structural and Functional Myocardial Improvement

Johnson, E., Visker, J. R., Brintz, B. J., Kyriakopoulos, C. P., Jeong, J., Zhang, Y., Shankar, T. S., Hillas, Y., Taleb, I., Badolia, R., Amrute, J. M., Stubben, C. J., Cedeno-Rosario, L., Kyriakoulis, I., Sideris, K., Ling, J., Hamouche, R., Tseliou, E., Navankasattusas, S., Ducker, G. S., Rutter, J., Holland, W. L., Summers, S. A., Hong, T., Koenig, S. C., Hanff, T. C., Lavine, K. J., Greene, T., Bailey, S., Alharethi, R., Selzman, C. H., Shah, P., Guo, H., Slaughter, M. S., Kanwar, M. K., Drakos, S. G.

10.64898/2026.04.21.720029 — Posted: 2026-04-26

Shared Risk Genes and Casual Relationships across Sex Hormone Related Traits and Alzheimer's Disease

yang, c., Cook, N., Zeng, Y., Sivasankaran, S. K., FinnGen, , Decasien, A., Andrews, S. J., Belloy, M. E.

10.64898/2026.04.23.26351626 — Posted: 2026-04-24

EMPIRE: The Ellipse Model for Phylogenetic Inference of Range Evolution

Swiston, S. K., McHugh, S. W., Landis, M. J.

10.64898/2026.04.23.720387 — Posted: 2026-04-24

Common and rare variant genetic contributions in African Americans with autism.

Cirnigliaro, M., Lowe, J. K., Flynn-Carroll, A. O., Kumagai, M. E., Gibson, D. S., Williams, J. B., Fu, J. M., Dong, S., Hou, K., Pillalamarri, V., Abbacchi, A. M., Gulsrud, A. C., Miller, J., Zhang, Y., Graham, E. T., Akinyemi, E. O., Adams, M. F., Clay, A. N., Arteaga, S. A., Choi, H., Kochis, R. M., Pena-Velasco, J. E., Hoekstra, J. N., Besterman, A. D., Mehta, S., Hadzic, T., Wilson, R. B., Brown, T. R., Hernandez, L. M., Marrus, N., Molholm, S., Klaiman, C., Cantor, R. M., Talkowski, M. E., Sanders, S. J., Arking, D. E., Pasaniuc, B., Klin, A., Constantino, J. N., Genetics of Neurodevelop

10.1101/2025.11.18.25340532 — Posted: 2026-04-24

Modulation of Avian Iridescence via Melanogenesis

Barbosa, S., Bittner, C., Arbore, R., Araujo, P., Pereira, P., Andrade, P., Fekete, C., Afonso, R., Afonso, S., Amorim, M., Marques, C., Nicolai, M., Carita, J., Brejcha, J., Lopes, R., Alves, J., Cruz, F., Gomez-Garrido, J., Zamarreno, C., Gut, M., Alyoto, T., Ali, M., Hilpert, A., Hech, A., Spiecker, E., Zubiri, B. A., Ito, S., Wakamatsu, K., Andersson, L., Corbo, J., Vogel, N., Carneiro, M.

10.64898/2026.01.26.701322 — Posted: 2026-04-24

Multimodal prediction of visual improvement in diabetic macular edema using real-world electronic health records and optical coherence tomography images

Sun, S., Cai, C. X., Fan, R., You, S., Tran, D., Rao, P. K., Suchard, M. A., Wang, Y., Lee, C. S., Lee, A. Y., Zhang, L.

10.64898/2026.04.23.26351616 — Posted: 2026-04-24

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