Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2884 Articles

MassID provides near complete annotation of metabolomics data with identification probabilities

Stancliffe, E., Gandhi, M., Guzior, D. V., Mehta, A., Acharya, S., Richardson, A. D., Cho, K., Cohen, T., Patti, G. J.

10.64898/2026.02.11.704864 — Posted: 2026-02-14

Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart

Kiessling, P., Joodaki, M., Pikulska, D., Scheidereit, E., Cesaro, G., Ruiz, M., Kuehn, D., Peng, K., Goni, O., Foecking, S., Samiei, S., Liao, X., Li, K., Feng, Z., Wang, D., Mavrommatis, L., Vllaho, A.-M., Rombach, M., Cucinella, G., Cheng, M., Lautenschlaeger, T., Morales, D. R., Veltrop, R. J. A., Schurgers, L. J., von Scheidt, M., Klinkhammer, B. M., Kahles, F., Kranz, J., Aguirre, A., Loft, A., Kluemper, N., Eckstein, M., Seidel, T., Forte, G., Westland, R., Zhang, M., Zhao, H., Ren, F., Hayat, S., Amrute, J. M., Kopecky, B., Schneider, R., Medyouf, H., Tharaux, P.-L., Boor, P., Kramann

10.64898/2026.01.31.701472 — Posted: 2026-02-14

A Multimodal Single-Cell Epigenomic and 3D Genome Atlas of the Human Basal Ganglia

Ding, W., Klein, A., Baez-Becerra, C. T., Rink, J. A., Bartlett, A., Zeng, Q., Wang, R., Castanon, R. G., Nery, J. R., Osgood, E., Owens, W., Petrella, A., Chen, C., Acerbo, A. S., Barcoma, A. S., Liu, J., Russo, K. G., Knutson, K. W., Young, C. K., Willier, J. K., Barragan, C., Arzavala, J., Cho, S., Altshul, J., Chan, D., Soma, E., Luo, J., Jain, M., Velazquez, S., Schenker-Ahmed, N., Sundaram, G. V., Manning, A. C., Sanchez, Y., Bikkina, A., Fu, S., OConnor, C., Liem, M., Marrin, M. V., Rose, C., Alt, S. N., Berry, J., Kern, C., Boone, E., Tian, W., Wu, Y., Hariharan, M., Fu, Y., Xie, Y., L

10.64898/2026.02.12.705594 — Posted: 2026-02-14

Targeting Multiple Immune Checkpoints with a Single Therapy: Implications for Treating Central Nervous System Tumors

Saxena, M., Ampudia-Mesias, E., Dhawan, S., Frederico, S. C., Cheng, X., Neil, E., Bose, R., Kohanbash, G., Moertel, C. L., Olin, M.

10.64898/2026.02.10.26345679 — Posted: 2026-02-14

AI-powered Gradient Echo Plural Contrast Imaging (AI-GEPCI): a Comprehensive Multiparametric Neurological Protocol from a Single MRI Scan

Lewis, J., Goyal, m. S., Wu, G. F., Hu, Y., Sukstanskii, A. L., Kothapalli, S. V., Cross, A. H., Kamilov, U., Yablonskiy, D. A.

10.64898/2026.02.11.26346017 — Posted: 2026-02-12

An LLM-assisted framework for accelerated and verifiable clinical hypothesis testing from electronic health records

Gim, N., Gim, I., Jiang, Y., Kihara, Y., Blazes, M., Wu, Y., Lee, C. S., Lee, A. Y.

10.64898/2026.02.10.26346008 — Posted: 2026-02-12

Federated penalized piecewise exponential model for horizontally distributed survival data: FedPPEM

Islam, N., Luo, C., Tong, J., Polleya, D. A., Jordan, C. T., Haverkos, B., Bair, S., Kent, A., Weller, G.

10.64898/2026.02.11.26346054 — Posted: 2026-02-12

Cellular Aging Signatures in the Plasma Proteome Record Human Health and Disease

Ding, D. Y., Bot, V. A., Chen, K. L., Groves, J., Palovics, R., Masuda, D., Farinas, A., Oh, H. S.-H., Wagner, V., Lu, N., The Global Neurodegeneration Proteomics Consortium (GNPC), , Cruchaga, C., Isakova, A., Schott, J. M., Wyss-Coray, T.

10.64898/2026.02.10.704909 — Posted: 2026-02-12

A framework for reparative CAR T engineering in the CNS

Shalita, R., Ben Yehuda, M., Boskovic, P., Frid, Y., Kuznetsov, Y., Tsoory, M., Kalchenko, V., Brenner, O., David, E., Mazuz, K., Majzner, R. G., Kipnis, J., Amit, I.

10.64898/2026.02.09.703122 — Posted: 2026-02-11

A cell-nonautonomous heme acquisition pathway enables erythroid hemoglobinization under stress

Belot, A., Rock, A., Dutt, S., Haemmerle, G., Maros, A., Yuan, X., Otsuru, S., Bodine, D., Hamza, I.

10.64898/2026.02.10.705195 — Posted: 2026-02-11

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