Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

2338 Articles

SMURF Reconstructs Single-Cells from Visium HD Data to Reveal Zonation of Transcriptional Programs in the Intestine

Guo, J., Sarafinovska, S., Hagenson, R., Valentine, M., Dougherty, J., Mitra, R. D., Muegge, B. D.

10.1101/2025.05.28.656357 — Posted: 2025-06-01

The Relationship between Alcohol Use Disorder, Measures of Cognitive Decline, and Alzheimer Disease Biomarkers in Older Adults

Hayibor, L. A., Anokhin, A., Fisher, S., Goate, A. M., Foroud, T. M., Schindler, S. E., Bierut, L. J., Hartz, S. M.

10.1101/2025.05.30.25328571 — Posted: 2025-05-31

Cortical synaptic vulnerabilities revealed in a α-synuclein aggregation model of Parkinson's disease

Sah, S., Sauerbeck, A. D., Gupta, J., Perez-Acuna, D., Reiber, J. E., Russell, D., Goralski, T., Henderson, M., Volpicelli-Daley, L. A., Higley, M. J., Kummer, T. T., Biederer, T.

10.1101/2024.06.20.599774 — Posted: 2025-05-31

Amino acid sensing by the α-cell mitochondrial phosphoenolpyruvate cycle regulates intracellular Ca2+ levels independently of glucagon secretion

Jin, E., Foster, H. R., Potapenko, E., Huang, S. M., Dong, X., Hughes, J. W., Merrins, M. J.

10.1101/2025.05.26.656009 — Posted: 2025-05-29

Mitochondrial presequences harbor variable strengths to maintain organellar function

Yan, Y., Erdenepurev, B., Collinson, I., Niemi, N. M.

10.1101/2025.05.26.655807 — Posted: 2025-05-29

Microglial SWELL1 Deficiency Drives Male-Specific Seizure Vulnerability but Paradoxical Neuroprotection through Impaired Phagocytosis

Barath, A. S., Dheer, A., Dale, E., Goche, F., Nguyen, T. T. L., Montier, L., Akter, M., Peshoff, M., Qi, F., Umpierre, A. D., Bosco, D. B., Haruwaka, K., Sah, R., Wu, L.-J.

10.1101/2025.05.26.656163 — Posted: 2025-05-29

PEDOT:PSS Microparticles for Extrudable and Bioencapsulating Conducting Granular Hydrogel Bioelectronics

Goestenkors, A. P., Yu, J. S., Park, J., Wu, Y., Espinoza, C. J. V., Friedman, L. C., Okafor, S. S., Liu, T., Chatterjee, S., Debnath, A., Semar, B. A., O'Hare, C. P., Alvarez, R. M., Singamaneni, S., Raman, B., Rutz, A. L.

10.1101/2025.05.25.655149 — Posted: 2025-05-28

Chondrocyte-Specific Knockout of Piezo1 and Piezo2 Protects Against Post-Traumatic Osteoarthritis Structural Damage and Pain in Mice

Ely, E., Lenz, K., Paradi, S., Ack, S., Behrmann, A., Dunivan, S., Braxton, L., Liedtke, W., Chen, Y., Collins, K. H., Guilak, F.

10.1101/2025.05.22.655585 — Posted: 2025-05-27

Unveiling functional-metabolic synergy in the healthy brain: multivariate integration of dynamic FDG-PET and resting-state fMRI

Tarricone, C., Vallini, G., Baron, G., Silvestri, E., Volpi, T., Vlassenko, A. G., Goyal, M. S., Bertoldo, A.

10.1101/2025.05.21.655345 — Posted: 2025-05-27

Transient effects in corticospinal and reticulospinal tract excitability induced by motor skill and isometric resistance training

Hawthorn, R., Phelps, N., Atkinson, C., Keesey, R. E., Seitz, Z., Nie, H., Seanez, I.

10.1101/2025.05.21.655351 — Posted: 2025-05-27

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