Channel: Washington University in St. Louis

This collection includes bioRxiv and medRxiv papers from authors at Washington University in St. Louis.

3045 Articles

Diverse infection models demonstrate robust resistance of Mycobacterium tuberculosis to innate immunity

Fairgrieve, M. R., Brydon, E. C., Chavez, R. A., Kotov, D. I., Vance, R.

10.1101/2025.11.20.687493 — Posted: 2026-06-11

Multi-ancestry genome-wide association study and meta-analysis of stimulant use disorder reveals biology and relationships to other psychiatric disorders

Beck, S. E., Deak, J. D., Levey, D. F., Ge, T., Jeffries, P. W., Lai, D., Mallard, T. T., Degenhardt, L., Lind, P. A., Tollerup Nielsen, T., Tubbs, J. D., Wetherill, L., Johnson, E. C., Hatoum, A. S., The SUD Working Group of the Psychiatric Genomics Consortium, , COGA Collaborators, , Yale-Penn Collaboration, , The VA Million Veteran Program, , Borglum, A., Demontis, D., Medland, S. E., Martin, N. G., Nelson, E. C., Smoller, J. W., Kranzler, H. R., Gaziano, J. M., Stein, M. B., Agrawal, A., Edenberg, H. J., Gelernter, J.

10.64898/2026.06.05.26354997 — Posted: 2026-06-10

Wnt/β-catenin signaling regulates fibrotic atrophy of intra-articular adipose tissue in post-traumatic osteoarthritis

Knights, A. J., Nguyen, D. M., Kahan, S., Newton, M. D., Tran, H. X., Mohan, A., Smith, I. J., Bhate, N., Lammlin, L., Redding, S. J., Stasikelis, L., Yang, T., Pervez, R., Buckles, M., Scheller, E. L., Hankenson, K. D., Maerz, T.

10.64898/2026.06.08.730865 — Posted: 2026-06-10

Alzheimer's disease neuroimaging signature aids identification of cognitive impairment in older adults with early-onset epilepsy

Williams, M., Arrotta, K., Bangen, K. J., Reyes, A., Stasenko, A., Zawar, I., Punia, V., Wang, I., Shin, W., Su, T.-Y., Shih, J. J., Farid, N., Kapur, J., Struck, A. F., Bekris, L. M., Ferguson, L., Almane, D. N., Jones, J. E., Hermann, B. P., Busch, R. M., McDonald, C. R., for the Alzheimer's Disease Neuroimaging Initiative*

10.64898/2026.06.05.26354952 — Posted: 2026-06-10

Long-read cDNA sequencing reveals novel isoforms and spliceosome-mutant-enriched transcripts in AML and MDS

Miller, C. A., Srivatsan, S. N., Kramer, M. H., Ramakrishnan, S. M., Fronick, C. C., Fulton, R. S., Katerndahl, C. D., Helton, N. M., Ley, T. J., Walter, M. J.

10.64898/2026.05.20.726635 — Posted: 2026-06-09

Single-cell transcriptomics of heterogeneous patient-derived organoids reveals novel therapeutic targets in high-grade serous ovarian cancer

Fashemi, B. E., Ota, Y., Gupta, V., Elizagaray, M. L., Pique-Regi, R., Gomez-Lopez, N., Mullen, M., Khabele, D.

10.64898/2026.06.05.730209 — Posted: 2026-06-09

Aperiodic and oscillatory activity of the human brain during induced emotional states

Park, H., Hacker, C., Cho, H., Xie, T., Simmons, A., Tan, G., Leuthardt, E. C., Brunner, P., Willie, J.

10.64898/2026.06.02.26354146 — Posted: 2026-06-09

Leptin Drives Osteoarthritis Pain Through Sensory Neuron Reprogramming Independent of Cartilage Signaling

Welhaven, H., Truchan, E. K., Lenz, K. L., Andoko, B. A., Mazzucco, M., Villa, R. E., Oestreich, A. K., Zhang, B., Orange, D. E., Lesnak, J. B., Price, T. J., Guilak, F., Collins, K. H.

10.64898/2026.05.22.727205 — Posted: 2026-06-09

Muscle-specific motor unit firing characteristics in elbow flexors and extensors after cervical spinal cord injury

Benedetto, A., Jenz, S., Farley, M., Heit, B., Sangari, S., Beauchamp, J. A., McPherson, L., Heckman, C., Perez, M., Pearcey, G.

10.64898/2026.06.03.729825 — Posted: 2026-06-08

Novel mouse models for perianal fistulizing Crohns disease reveal therapeutic value of interferon-gamma antagonists

Yao, X., Ma, K., Ballard, D. H., Zhu, E., Liu, X., Huang, L., Tian, C., Quirk, J. D., Ruiz, H. S., Tan, T., Ciorba, M. A., Randolph, G., Deepak, P., Cao, S.

10.64898/2026.06.04.730162 — Posted: 2026-06-08

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