Channel:  Francis Crick Institute

1,206 Articles

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Multimodal profiling unveils a reversible breast basal-like cell state in AKT-inhibitor resistant tumours
Ratcliffe, C. D. H., Sparks, H., Boezio, G. L. M., Alexandrov, Y., Jenkins, R. P., Le Marois, A., Soro-Barrio, P., Moughari, F. A., Hulme, H., Lee, R. J., Strohbuecker, S., Joshi, S., Ellis, J. K., Fabrini, G., Flint, L., Fortier, A.-M., Gustafsson, N., Cunha, A. C., Tully, L., Park, M., Frohlich, F., MacRae, J. I., Natrajan, R., Serio, A., Briscoe, J., Riddell, A., Barry, S. T., Dunsby, C., Sahai, E.
10.1101/2025.06.06.658331 — Posted: 2025-11-17
PMGen: From Peptide-MHC Prediction to Neoantigen Generation
Asgary, A. H., Aleyasin, A., Mehl, J. A., Ludewig, B., Mishto, M., Liepe, J., Soeding, J.
10.1101/2025.11.14.688404 — Posted: 2025-11-14
Siglec-engaging immunosuppressive sialoglycans are upregulated in prostate cancer and are targetable to suppress bone metastasis
Peng, Z., Hodgson, K., Fisher, M., Mei, S., Orozco-Moreno, M., Cao, L., Kemp, M., Gatlin, W., Donald, L., Zeng, F., Lawson, M. A., Ungar, D., Sykes, D. B., Elliott, D. J., Peng, L., Schumann, B., Wang, N., Munkley, J.
10.1101/2025.11.12.687981 — Posted: 2025-11-13
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur, X., Ganier, C., Mazin, P., Cheshire, C., Rashidghamat, E., Luscombe, N. M., Lynch, M. D., Watt, F. M.
10.1101/2025.11.11.682326 — Posted: 2025-11-12
Inhibiting epithelial cell extrusion and inflammation synergistically reverses asthmatic airway remodelling
Bagley, D. C., Russell, T., Martinez-Nunez, R. T., Marcotti, S., Rosenblatt, J.
10.1101/2025.11.10.687569 — Posted: 2025-11-11
Spillover of H5 influenza viruses to vampire bats at the marine-terrestrial interface
Tu, I.-T., Lynggaard, C., Adams, L., Walsh, S. K., Chen, H., Raveendran, S., Turnbull, M. L., Griffiths, M. E., Ribeiro, R., Perez, J. G., Bazan, W. V., Tello, C., Zariquiey, C., Rodriguez, K. P., Risco, M., Mamani, I. Q., Chavez, W., Villafuerte, R. Z., Manuttupa, J. C., Castro Namuche, J. P., Moreira-Soto, A., Drexler, J. F., Delhon, G., Faust, C., Cardenas-Alayza, S., Hutchinson, E., Murcia, P. R., Palmarini, M., Bohmann, K., Harvey, R., Streicker, D. G.
10.1101/2025.11.09.686930 — Posted: 2025-11-11
Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes
Gomez-Gil, E., Guerra, P., Gu, Y., Foo, S., Billard, B., Balogh, G., Peter, M., Oliferenko, S.
10.1101/2025.11.06.686945 — Posted: 2025-11-07
Topological defects drive influenza glycoprotein lattice assembly on spherical membranes
Liu, Z. B., Halldorsson, S., Calcraft, T., Calder, L. J., Rosenthal, P. B.
10.1101/2025.11.06.686978 — Posted: 2025-11-07
A structural and regulatory framework for Atg9-containing vesicle formation and their Atg1-dependent remodelling during autophagy initiation
Oeo-Santos, C., Knüpling, E., Davis, C., Meng, X., Maslen, S., Kunzelmann, S., D'Antuono, R., Olerinyova, A., Auchynnikava, T., Skehel, M., Schreiber, A.
10.1101/2025.11.06.685569 — Posted: 2025-11-06
CRITICAL ROLE OF ADULT-BORN DENTATE GRANULE NEURONS IN PATTERN COMPLETION
Roullet, P., Koehl, M., Delage, P., Guillemot, F., Abrous, N.
10.1101/2025.05.15.654267 — Posted: 2025-11-05

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