Channel:  The Howard Hughes Medical Institute (HHMI)

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Wide Transition-State Ensemble as Key Component for Enzyme Catalysis
Jara, G. E., Pontiggia, F., Otten, R., Agafonov, R. V., Marti, M. A., Kern, D.
10.1101/2023.10.03.560706 — Posted: 2024-12-02
TTF2 promotes replisome eviction from stalled forks in mitosis
Can, G., Shyian, M., Krishnamoorthy, A., Lim, Y., Wu, A., Zaher, M., Raeschle, M., Walter, J., Pellman, D.
10.1101/2024.11.30.626186 — Posted: 2024-11-30
Reliable amplification of highly repetitive or low complexity sequence DNA enabled by superhelicase-mediated isothermal amplification
Kang, J., Rashid, F., Murray, P. J., Merino-Urteaga, R., Gavrilov, M., Shang, T., Jo, W., Ahmed, A., Aksel, T., Barrick, D., Berger, J. M., Ha, T.
10.1101/2024.11.27.625726 — Posted: 2024-11-29
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
MacLean, A. J., Deimel, L. P., Zhou, P., ElTanbouly, M. A., Merkenschlager, J., Ramos, V., Santos, G. S., Hagglof, T., Mayer, C. T., Hernandez, B., Gazumyan, A., Nussenzweig, M. C.
10.1101/2024.11.26.625430 — Posted: 2024-11-29
An updated reference genome sequence and annotation reveals gene losses and gains underlying naked mole-rat biology
Sokolowski, D. J., Miclaus, M., Nater, A., Faykoo-Martinez, M., Hoekzema, K., Zuzarte, P., Monis, S., Alvi, S. A., Erdmann, J., Erdmann, A. L., Kumaragurubaran, R., Bayerl, J., Yoo, D., Karimpour, N., Ungerleider, K., Hou, H., Fergal, M., Hourlier, T., Clarke, Z. A., Lischer, H. E., Leordean, D. V., Jiang, Y., Pugh, T. J., Smith, E. S. J., Haggerty, L., Laird, D. J., Lilue, J., Holmes, M. M., Eichler, E. E., Bruggmann, R., Simpson, J. T., Balmus, G., Wilson, M. D.
10.1101/2024.11.26.625329 — Posted: 2024-11-28
Design of high specificity binders for peptide-MHC-I complexes
Liu, B., Greenwood, N. F., Bonzanini, J. E., Motmaen, A., Sharp, J., Wang, C., Visani, G. M., Vafeados, D. K., Roullier, N., Nourmohammad, A., Garcia, K. C., Baker, D.
10.1101/2024.11.28.625793 — Posted: 2024-11-28
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
Kim, S., Todisco, M., Radakovic, A., Szostak, J. W.
10.1101/2024.11.26.625528 — Posted: 2024-11-28
Unraveling SARS-CoV-2 Host-Response Heterogeneity through Longitudinal Molecular Subtyping
Wang, K., Nie, Y., Maguire, C., Syphurs, C., Sheen, H., Karoly, M., Lapp, L., Gygi, J. P., Jayavelu, N. D., Patel, R. K., Hoch, A., IMPACC Network, , Corry, D., Kheradmand, F., McComsey, G. A., Fernandez-Sesma, A., Simon, V., Metcalf, J. P., Agudelo Higuita, N. I., Messer, W. B., David, M. M., Nadeau, K. C., Kraft, M., Bime, C., Schaenman, J., Erle, D., Calfee, C. S., Atkinson, M. A., Brackenridge, S. C., Hafler, D. A., Shaw, A. C., Rahman, A., Hough, C. L., Geng, L. N., Ozonoff, A., Haddad, E. K., Reed, E. F., Bakel, H. v., Kim-Schulze, S. H., Krammer, F., Wilson, M., Eckalbar, W., Bosinger
10.1101/2024.11.22.624784 — Posted: 2024-11-25
Dynamic regulation of the oxidative stress response by the E3 ligase TRIP12
Ingersoll, A. J., McCloud, D. M., Hu, J. Y., Rape, M.
10.1101/2024.11.25.625235 — Posted: 2024-11-25
Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species
Toker, I. A., Ripoll-Sanchez, L., Geiger, L. T., Saini, K. S., Beets, I., Vertes, P. E., Schafer, W. R., Ben-David, E., Hobert, O.
10.1101/2024.11.23.624988 — Posted: 2024-11-25

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