COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,757 Articles (22,943 medRxiv, 8,814 bioRxiv)

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A historical cross-border Andes virus lineage reveals the origin of a cruise ship hantavirus pulmonary syndrome outbreak
Ramos, H., Diaz-Gavidia, C., Diaz-Ramirez, D., Fuentes-Luppichini, E., Kuhn, J. H., Bellomo, C. M., Schüller, A., Araya-Secchi, R., International Genomics Consortium Investigating the M/V Hondius Outbreak, , Cisterna, D. M., Fernandez-Bettelli, L., Palacios-Aliggi, S., Martinez, V. P., Ferres, M., Maes, P., Palacios, G., Tischler, N. D., Angulo, J.
10.64898/2026.07.19.739363 — Posted: 2026-07-21
Coronavirus papain-like protease antagonizes innate immunity by cleaving Importin α1 to disrupt nuclear transport
Liao, Y., Wang, J., Xue, W., Sun, Y., Tan, L., Song, C., Qiu, X., Ding, C.
10.64898/2026.07.17.739146 — Posted: 2026-07-20
A human monoclonal antibody from hybrid immunity exhibits exceptional neutralization breadth against antigenically divergent contemporary Omicron JN.1 lineage variants
Rathour, D., Shrivas, S., Kumar, N., Prasad, C., Singh, J., Singh, G., Surendranath, A., Rathi, S., Verma, S., Chauhan, S., Singh, B., Sutar, J., Chattopadhyay, S., Batra, G., Sonar, S., Eckerle, I., Subbissi, L., Mohan, A., Asthana, S., Deshpande, S., BHATTACHARYA, J.
10.64898/2026.07.20.739483 — Posted: 2026-07-20
Variant-specific spike conformational dynamics shape memory B cell selection during recall
Broutin, M., Sokal, A., Dejoux, A., Planas, D., Vanderkerken, M., Fernandez, I., Azzaoui, I., Vandenberghe, A., Charlet, M., Arbabian, A., Megret, J., Toure, L., Planchais, C., Berard, L., Simon, T., Weill, J.-C., Mouquet, H., Schwartz, O., Bruhns, P., Rey, F. A., Launay, O., Mahevas, M., Chappert, P.
10.64898/2026.07.18.739204 — Posted: 2026-07-20
Sustained Delivery of a SARS-CoV-2 Subunit Vaccine in An Adjuvanted Hydrogel Depot Enhances Vaccine Responses in Nonhuman Primates
Ou, B. S., Hu, M., Yan, J., Santagata, J. M., Saouaf, O. M., Eppler, H. B., Lujan, V., Song, Y. E., Grifoni, A., Klich, J., Sette, A., Utz, A., Suthar, M. S., Eckman, N., Feng, Y., Baillet, J., Rogers, K. A., Shirreff, L. M., Aoyagi, G. J., Valdez, A. S., Ravichandran, R., King, N. P., Fontenot, J., Villinger, F., Pulendran, B., Appel, E.
10.64898/2026.07.17.736840 — Posted: 2026-07-20
Direct estimation of genotype fitness from time series
Mohanty, V., Shakhnovich, E.
10.64898/2026.07.18.739367 — Posted: 2026-07-20
Long-term SARS-CoV-2 Persistence in Syrian Hamsters
Melquiades de Lima, T., Capelini Eli Lopes, C. E., Oliveira de Souza, M. V., Rocha do Nascimento, F., Meria Ramos Rodrigues, D., Conde Silva, G., Dias, M., Antonio Nasser Neto, T., Silva, M. L., Macedo de Melo Jorge, D., de Paula Souza, J., Arruda, E.
10.64898/2026.07.19.739454 — Posted: 2026-07-20
Anticipatory discovery of entry inhibitors against emerging viruses guided by viral phylogeny
Arce, R., Andreu-Moreno, I., Dufloo, J., Sanjuan, R.
10.64898/2026.07.17.739150 — Posted: 2026-07-20
Human coronavirus nucleocapsid proteins have disparate innate immune evasion abilities
Sharlin, N., Mulloy, R. P., Day, M., Corcoran, J.
10.64898/2026.07.14.738543 — Posted: 2026-07-16
A novel AR molecular glue degrader via bivalent engagement of the N-terminal domain and RNF213-UBE2J2 complex
Wu, K., Wu, Q., Lu, Y., Yang, Q., Ran, T., Zhang, J., Qiu, X., Huang, C., Lin, Y., Chen, J., Yang, Z., Zhang, J., Qin, W., Liu, Z., Liu, X., Tang, M., Chen, H., Zheng, J., Chen, X., Shang, J.
10.64898/2026.07.14.738453 — Posted: 2026-07-16

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).