Channel: Simons Foundation Autism Research Initiative (SFARI)

280 Articles

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Molecular and connectomic vulnerability shape cross-disorder cortical abnormalities

Hansen, J. Y., Shafiei, G. Y., Vogel, J. W., Smart, K., Bearden, C. E., Hoogman, M., Franke, B., van Rooij, D., Buitelaar, J., McDonald, C. R., Sisodiya, S., Schmaal, L., Veltman, D. J., van den Heuvel, O. A., Stein, D. J., van Erp, T. G., Ching, C., Andreassen, O. A., Hajek, T., Opel, N., Modinos, G., Aleman, A., van der Werf, Y., Jahanshad, N., Thomopoulos, S. I., Thompson, P. M., Carson, R. E., Dagher, A., Misic, B.

10.1101/2022.01.21.476409 — Posted: 2022-01-21

Astrocyte glutamate transport is modulated by motor learning and regulates neuronal correlations and movement encoding by motor cortex neurons

Delepine, C., Li, K., Shih, J., Gaudeaux, P., Sur, M.

10.1101/2022.01.20.477039 — Posted: 2022-01-21

Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders

Baker, B. H., Zhang, S., Simon, J. M., McLarnan, S. M., Chung, W. K., Pearson, B. L.

10.1101/2021.12.17.473207 — Posted: 2021-12-20

The PAIR-R24M Dataset for Multi-animal 3D Pose Estimation

Marshall, J. D., Klibaite, U., Gellis, A. J., Aldarondo, D. E., Olveczky, B. P., Dunn, T. W.

10.1101/2021.11.23.469743 — Posted: 2021-11-25

Patient brain organoids identify a link between the 16p11.2 copy number variant and the RBFOX1 gene.

Kostic, M., Raymond, J. J., Henry, B., Tumkaya, T., Khlghatyan, J., Dvornik, J., Hsiao, J., Cheon, S. H., Chung, J., Sun, Y., Dolmetsch, R., Worringer, K. A., Ihry, R.

10.1101/2021.11.21.469432 — Posted: 2021-11-23

Cortical wiring by synapse-specific control of local protein synthesis

Bernard, C., Exposito-Alonso, D., Selten, M., Sanalidou, S., Hanusz-Godoy, A., Oozeer, F., Maeso, P., Rico, B., Marin, O.

10.1101/2021.11.12.468364 — Posted: 2021-11-13

Sex significantly impacts the function of major depression-linked variants in vivo

Mulvey, B., Selmanovic, D., Dougherty, J. D.

10.1101/2021.11.01.466849 — Posted: 2021-11-04

Biophysical Kv channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer's

Olah, V. J., Goettemoeller, A. M., Dimidschstein, J., Rowan, M. J.

10.1101/2021.10.25.465789 — Posted: 2021-10-26

A general framework for identifying rare variant combinations in complex disorders

Pounraja, V. K., Girirajan, S.