Channel:  ENCODE

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

136 Articles

Transgenic mice for in vivo epigenome editing with CRISPR-based systems
Gemberling, M., Siklenka, K., Rodriguez, E., Eisinger, K., Barrera, A., Liu, F., Kantor, A., Li, L., Cigliola, V., Hazlett, M., Williams, C., Bartelt, L., Bodle, J., Daniels, H., Rouse, C., Hilton, I., Madigan, V., Asokan, A., Ciofani, M., Poss, K., Reddy, T. E., West, A., Gersbach, C.
10.1101/2021.03.08.434430 — Posted: 2021-03-08
Genome-wide annotation of gene regulatory elements linked to cell fitness
Klann, T., Barrera, A., Ettyreddy, A., Rickels, R., Bryois, J., Jiang, S., Adkar, S., Iglesias, N., Sullivan, P., Reddy, T. E., Crawford, G. E., Gersbach, C.
10.1101/2021.03.08.434470 — Posted: 2021-03-09
Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics
Jagadeesh, K. A., Dey, K. K., Montoro, D. T., Mohan, R., Gazal, S., Engreitz, J. M., Xavier, R. J., Price, A. L., Regev, A.
10.1101/2021.03.19.436212 — Posted: 2021-11-23
Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution
Griesemer, D., Xue, J. R., Reilly, S. K., Ulirsch, J. C., Kukreja, K., Davis, J., Kanai, M., Yang, D. K., Montgomery, S. B., Novina, C. D., Tewhey, R., Sabeti, P. C.
10.1101/2021.01.13.424697 — Posted: 2021-01-13
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
Rozowsky, J., Drenkow, J., Yang, Y., Gursoy, G., Galeev, T., Borsari, B., Epstein, C., Xiong, K., Xu, J., Gao, J., Yu, K., Berthel, A., Chen, Z., Navarro, F., Liu, J., Sun, M., Wright, J., Chang, J., Cameron, C., Shoresh, N., Gaskell, E., Adrian, J., Aganezov, S., Balderrama-Gutierrez, G., Banskota, S., Corona, G., Chee, S., Chhetri, S., Martins, G., Danyko, C., Davis, C., Farid, D., Farrell, N., Gabdank, I., Gofin, Y., Gorkin, D., Gu, M., Hecht, V., Hitz, B., Issner, R., Kirsche, M., Kong, X., Lam, B., Li, S., Li, B., Li, T., Li, X., Lin, K., Luo, R., Mackiewicz, M., Moore, J., Mudge, J., Nel
10.1101/2021.04.26.441442 — Posted: 2022-11-22
Mapping and modeling the genomic basis of differential RNA isoform expression at single-cell resolution with LR-Split-seq
Rebboah, E., Reese, F., Williams, K., Balderrama-Gutierrez, G., McGill, C., Trout, D., Rodriguez, I. M., Liang, H., Wold, B. J., Mortazavi, A.
10.1101/2021.04.26.441522 — Posted: 2021-04-27
Axes of inter-sample variability among transcriptional neighborhoods reveal disease associated cell states in single-cell data
Reshef, Y. A., Rumker, L., Kang, J. B., Nathan, A., Korsunsky, I., Asgari, S., Murray, M. B., Moody, D. B., Raychaudhuri, S.
10.1101/2021.04.19.440534 — Posted: 2021-05-27
Topologically Associating Domain Boundaries are Commonly Required for Normal Genome Function
Rajderkar, S., Barozzi, I., Zhu, Y., Hu, R., Zhang, Y., Li, B., Fukuda-Yuzawa, Y., Kelman, G., Akeza, A., Blow, M. J., Pham, Q., Harrington, A. N., Godoy, J., Meky, E. M., von Maydell, K., Novak, C. S., Plajzer-Frick, I., Afzal, V., Tran, S., Talkowski, M. E., Llyod, K. C. K., Ren, B., Dickel, D. E., Visel, A., Pennacchio, L. A.
10.1101/2021.05.06.443037 — Posted: 2021-05-07
High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer
Pierce, S. E., Granja, J. M., Greenleaf, W. J.
10.1101/2020.11.02.364265 — Posted: 2020-11-02
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2
Delorey, T. M., Ziegler, C. G. K., Heimberg, G., Normand, R., Yang, Y., Segerstolpe, A., Abbondanza, D., Fleming, S. J., Subramanian, A., Montoro, D. T., Jagadeesh, K. A., Dey, K., Sen, P., Slyper, M., Pita-Juarez, Y., Phillips, D., Bloom-Ackermann, Z., Barkas, N., Ganna, A., Gomez, J., Normandin, E., Naderi, P., Popov, Y. V., Raju, S. S., Niezen, S., Tsai, L. T.- Y., Siddle, K. J., Sud, M., Tran, V. M., Karuthedath Vellarikkal, S., Amir-Zilberstein, L., Atri, D. S., Beechem, J. M., Brook, O. R., Chen, J., Divakar, P., Dorceus, P., Engreitz, J. M., Essene, A., Fitzgerald, D. M., Fropf, R., Gaz
10.1101/2021.02.25.430130 — Posted: 2021-02-25

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