Channel:  UK Biobank

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

170 Articles

FunSPU: a versatile and adaptive multiple functional annotation-based association test of whole-genome sequencing data
Ma, Y., Wei, P.
10.1101/350355 — Posted: 2018-06-19
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
Haworth, S., Shapland, C. Y., Hayward, C., Prins, B. P., Felix, J. F., Medina-Gomez, C., Rivadeneira, F., Wang, C., Ahluwalia, T. S., Vrijheid, M., Guxens, M., Sunyer, J., Tachmazidou, I., Walter, K., Iotchkova, V., Jackson, A., Cleal, L., Huffmann, J., Min, J. L., Sass, L., Timmers, P. R. H. J., UK10K consortium, , Davey Smith, G., Fisher, S. E., Wilson, J. F., Cole, T. J., Fernandez-Orth, D., Bonnelykke, K., Bisgaard, H., Pennell, C. E., Jaddoe, V. W. V., Dedoussis, G., Timpson, N. J., Zeggini, E., Vitart, V., St Pourcain, B.
10.1101/349845 — Posted: 2018-06-18
New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries
Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Understanding Society Scientific Group, , Weiss, S., Kentistou, K. A., Cook, J. P., Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bosse, Y., Brandsma, C.-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo
10.1101/343293 — Posted: 2018-06-12
An Atlas of Human and Murine Genetic Influences on Osteoporosis
Morris, J. A., Kemp, J. P., Youlten, S. E., Laurent, L., Logan, J. G., Chai, R., Vulpescu, N. A., Forgetta, V., Kleinman, A., Mohanty, S., Sergio, C. M., Quinn, J., Nguyen-Yamamoto, L., Luco, A.-L., Vijay, J., Simon, M.-M., Pramatarova, A., Medina-Gomez, C., Trajanoska, K., Ghirardello, E. J., Butterfield, N. C., Curry, K. F., Leitch, V. D., Sparkes, P. C., Adoum, A.-T., Mannan, N. S., Komla-Ebri, D., Pollard, A. S., Dewhurst, H. F., Hassell, T., Beltejar, M.-J. G., Adams, D. J., Vaillancourt, S. M., Kaptoge, S., Baldock, P., Cooper, C., Reeve, J., Ntzani, E., Evangelou, E., Ohlsson, C., Karas
10.1101/338863 — Posted: 2018-07-27
PCSK9 genetic variants, life-long lowering of LDL-cholesterol and cognition: a large-scale Mendelian randomization study
Lyall, D., Ward, J., Banach, M., Davey Smith, G., Gill, J., Pell, J., Holmes, M., Sattar, N.
10.1101/335877 — Posted: 2018-05-31
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., 155 additional authors, , Hemingway, H., Asselbergs, F., Patel, R., Keating, B. J., Sattar, N., Houlston, R., Casas, J., Hingorani, A. D.
10.1101/329052 — Posted: 2018-05-25
Modelling the distribution of white matter hyperintensities due to ageing on MRI images using Bayesian inference
Sundaresan, V., Griffanti, L., Kindalova, P., Alfaro-Almagro, F., Zamboni, G., Rothwell, P. M., Nichols, T. E., Jenkinson, M.
10.1101/327205 — Posted: 2018-05-21
Refining fine-mapping: effect sizes and regional heritability
Benner, C., Havulinna, A., Salomaa, V., Ripatti, S., Pirinen, M.
10.1101/318618 — Posted: 2018-05-10
Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes
Udler, M. S., Kim, J., von Grotthuss, M., Bonas-Guarch, S., Mercader, J. M., Cole, J. B., Chiou, J., Anderson, C. D., Boehnke, M., Laakso, M., Atzmon, G., Glaser, B., Gaulton, K., Flannick, J., Getz, G., Florez, J. C.
10.1101/319509 — Posted: 2018-05-11
Shared genetic contribution to type 1 and type 2 diabetes risk
Aylward, A. J., Chiou, J., Okino, M.-L., Kadakia, N., Gaulton, K. J.
10.1101/285304 — Posted: 2018-05-07

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