Channel: University of Chicago

This collection includes bioRxiv and medRxiv papers from authors at University of Chicago.

2974 Articles

Structural basis of directionality control in large serine integrases

Shin, H., Pigli, Y., Pena Reyes, T., Bello, A. J., Fuller, J. R., Olorunniji, F. J., Rice, P. A.

10.1101/2025.01.03.631226 — Posted: 2026-02-05

Association of Long-Term Air Pollution Exposure with Dementia-Related Neuropathologies at Autopsy in a Community-Based Cohort

Jenson, T. E., Andrews, R. M., Adar, S. D., Barnes, L. L., Bennett, D. A., Burnham, D., Cursio, J., Gassett, A., Graham, U., Kaufman, J. D., Lamar, M., Marquez, D. X., Nag, S., Oberdörster, G., Pescador Jimenez, M. I., Schneider, J. A., Szpiro, A. A., Pinto, J. M., Weuve, J.

10.64898/2026.02.03.26345515 — Posted: 2026-02-05

Trans-eQTLs reveal the architecture of human gene regulatory networks

Warmerdam, C. A. R., Westra, H.-J., van der Graaf, A., Bonder, M. J., Deelen, P., van Lieshout, T., Landman, A. J., Jesse, M., Strober, B. J., Boltz, T., Lapinska, S., Nagpal, S., Xie, M., Tay, D., Kirsten, H., Naeem, H., Raghavan, V., Farzeen, A., Teumer, A., Fave, M.-J., Persyn, E., Tokolyi, A., Pool, R., Hottenga, J. J., Rodriguez, R. D., Rivas-Torrubia, M., Hamal Mishra, B., Pierce, B., Tong, L., Wang, Q. S., Hasegawa, T., Chhetri, S. B., Dutta, D., Weiss, S., Dupuis, T., Lyytikäinen, L.-P., Mishra, P. P., Wood, A. R., Burnham, K. L., Wen, J., Cheruiyot, E., Boahen, C. K., Jansen, R., Kro

10.64898/2026.02.04.26343575 — Posted: 2026-02-05

The CD8 immgenT framework as a universal reference of mouse CD8 Tαβ cell differentiation states

Galletti, G., Globig, A.-M., Barreiro, O., Heim, T. A., Liu, S., Borys, S. M., Casey, O., Monell, A. T., Patravali, D., Scharping, N. E., Quon, S., Takehara, K. K., Ferry, A., Cheung, K. P., Duong, E., Shinkawa, T., Spranger, S., Behar, S. M., Kaech, S. M., Goldrath, A. W., Zemmour, D., ImmgenT Project

10.64898/2026.02.02.703365 — Posted: 2026-02-04

Diverse Microbial Exposure Enhances CD8+ T Cell Effector Memory Output and Function

Thefaine, C. E., Lucas, E. D., Block, K. E., Pierson, M., Dehm, E., Huggins, M., Casey, O. W., Zemmour, D., Jameson, S. C., Hamilton, S. E.

10.64898/2026.02.02.703037 — Posted: 2026-02-04

Histotripsy-initiated immune response synergizes with chemotherapy in a neuroblastoma murine model

Antonides-Jensen, N., Singh, M., Xue, Y., Flores-Guzman, F., Wu, L. L., Yee, S. S., Gomez-Villa, J., Hall, T. L., Applebaum, M. A., Bader, K. B., Hernandez, S. L.

10.64898/2026.01.30.702878 — Posted: 2026-02-03

Transcriptomic and protein analysis of human cortex reveals genes and pathways linked to NPTX2 disruption in Alzheimer's disease

Lao, Y., Xiao, M.-F., Ji, S., Piras, I. S., Kim, K., Bonfitto, A., Song, S., Aldabergenova, A., Sloan, J., Trejo, A., Geula, C., Na, C.-H., Rogalski, E. J., Kawas, C. H., Corrada, M. M., Serrano, G. E., Beach, T. G., Troncoso, J. C., Huentelman, M. J., Barnes, C. A., Worley, P. F., Colantuoni, C.

10.1101/2025.10.17.683150 — Posted: 2026-02-03

Cave evolution on repeat: reuse of the same genomic regions across lineages but not across traits in Astyanax mexicanus

Richards, E. J., Moran, R. L., Wiese, J., O'Gorman, M., Hutton, P., Rastogi, A., North, O. W., Manning, A. E., Roback, E. Y., Kowalko, J. E., Rohner, N., Keene, A. C., McGaugh, S. E.

10.64898/2026.01.31.703033 — Posted: 2026-02-03

Distinct neural modes carry information about grasp force and phase in the sensorimotor cortex

Blumenthal, G. H., Dekleva, B. M., Gontier, C., Gonzalez, I. C., Gonzalez-Martinez, J. A., Yu, B. M., Batista, A. P., Sobinov, A. R., Miller, L. E., Gaunt, R. A., Boninger, M. L., Chase, S. M., Collinger, J. L.

10.64898/2026.02.01.702680 — Posted: 2026-02-03

Low-Strength Type I Interferon Signaling Promotes CAR T-Cell Treatment Efficacy

Tang, E., Hu, Y., Cao, G., Asby, N. W., Nguyen, D.-T., Aboelella, N. S., Ruiz, H., Cai, X., Zhang, W., Zhao, Y., Xie, L., Chen, X., Bishop, M. R., Riedell, P. A., LaBelle, J. L., Kline, J. P., Huang, J.

10.1101/2025.05.13.653878 — Posted: 2026-02-03

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