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179 Reviews — eLife — Genomics

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Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR
Akhtar, F., Ruiz, J. H., Liu, Y.-G., Resendez, R. G., Feliers, D., Morales, L. D., Diaz-Badillo, A., Lehman, D. M., Arya, R., Alvarenga, J. C. L., Blangero, J., Duggirala, R., Mummidi, S.
10.1101/2023.10.31.564937 — Posted: 2023-11-02 — Discussion: 2025-08-26  eLife
DNA methylation insulates genic regions from CTCF loops near nuclear speckles
Roseman, S. A., Siegenfeld, A. P., Lee, C., Lue, N. Z., Waterbury, A. L., Liau, B. B.
10.1101/2023.07.26.550645 — Posted: 2023-07-26 — Discussion: 2025-08-06  eLife
Epigenetic context predicts gene expression variation and reproductive traits across genetically identical individuals
Webster, A. K., Willis, J. H., Johnson, E., Sarkies, P., Phillips, P. C.
10.1101/2023.10.13.562270 — Posted: 2023-10-13 — Discussion: 2025-07-16  eLife
A pipeline to identify TF combinatorial binding uncovers TEAD1 as an antagonist of tissue-specific transcription factors in human organogenesis
Garcia-Mora, A., Mallen, J., Zarrineh, P., Hanley, N. A., Gerrard, D., Bobola, N.
10.1101/2023.10.05.561094 — Posted: 2023-10-07 — Discussion: 2025-06-10  eLife
Deeply hidden genome organization directly mediated by SATB1
Kohwi, Y., Grange, M., Richards, H. W., Liang, Y.-C., Chuong, C.-M., Kitagawa, Y., Sakaguchi, S., Botchkarev, V., Taniguchi, I., Kohwi-Shigematsu, T.
10.1101/2021.12.19.473323 — Posted: 2021-12-21 — Discussion: 2025-05-23  eLife
Exploiting functional regions in the viral RNA genome as druggable entities
Wei, D., Luo, D., Zheng, Y., Huang, Z., Wen, Z., Guo, L., Deng, Y., Li, Q., Bai, Y., Haider, S., Parkinson, G. N.
10.1101/2024.08.11.607475 — Posted: 2024-08-11 — Discussion: 2025-05-16  eLife
Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of ZDBF2
Kobayashi, H., Igaki, T., Kumamoto, S., Tanaka, K., Takashima, T., Suzuki, S., Hayashi, M., Renfree, M. B., Kawahara, M., Saito, S., Kobayashi, T., Nagashima, H., Nakano, K., Matsunari, H., Uchikura, A., Kiyonari, H., Kaneko, M., Imai, H., Nakabayashi, K., Lorincz, M. C., Kurimoto, K.
10.1101/2023.10.30.564869 — Posted: 2023-11-02 — Discussion: 2025-05-12  eLife
Convergent evolution of epigenome recruited DNA repair across the Tree of Life
Monroe, G., Lee, C., Quiroz, D. P., Lensink, M., Oya, S., Davis, M., Long, E., Bird, K. A., Pierce, A. V., Zhao, K., Runcie, D. E.
10.1101/2024.10.15.618488 — Posted: 2024-11-02 — Discussion: 2025-04-17  eLife
Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma
Li, K., Tolman, N., V. Segre, A., Stuart, K., Zeleznik, O. A., Vallabh, N. A., Hu, K., Zebardast, N., Hanyuda, A., Raita, Y., Montgomery, C., Zhang, C., Hysi, P. G., Do, R., Khawaja, A., Wiggs, J., Kang, J., John, S., Pasquale, L.
10.1101/2025.01.18.633745 — Posted: 2025-01-22 — Discussion: 2025-03-28  eLife
Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function
Gholamalamdari, O., van Schaik, T., Wang, Y., Kumar, P., Zhang, L., Zhang, Y., Gonzalez, G. A. H., Vouzas, A. E., Zhao, P. A., Gilbert, D. M., Ma, J., van Steensel, B., Belmont, A. S.
10.1101/2024.04.23.590809 — Posted: 2024-04-23 — Discussion: 2025-03-25  eLife

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