Channel:  International Mouse Phenotyping Consortium (IMPC)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

96 Articles

A resource of targeted mutant mouse lines for 5,061 genes
Birling, M.-C., Yoshiki, A., Adams, D. J., Ayabe, S., Beaudet, A. L., Bottomley, J., Bradley, A., Brown, S. D. M., Bürger, A., Bushell, W., Chiani, F., Chin, H.-J. G., Christou, S., Codner, G. F., DeMayo, F. J., Dickinson, M., Doe, B., Donahue, L. R., Fray, M. D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L. O., Heaney, J. D., Hérault, Y., Hrabe de Angelis, M., Jiang, S.-T., Justice, M. J., Kasparek, P., King, R. E., Kühn, R., Lee, H., Lee, Y. J., Liu, Z., Lloyd, K. C. K., Lorenzo, I., Mallon, A.-M., McKerlie, C., Meehan, T. F., Newman, S., Nutter, L. M
10.1101/844092 — Posted: 2019-11-22
Application of long-read sequencing for robust identification of correct alleles in genome edited animals
McCabe, C. V., Codner, G. F., Allan, A. J., Caulder, A., Christou, S., Loeffler, J., Mackenzie, M., Malzer, E., Mianne, J., Pike, F. J., Hutchison, M., Stewart, M. E., Gates, H., Wells, S., Sanderson, N. D., Teboul, L.
10.1101/838193 — Posted: 2019-11-14
A big-data approach to understanding metabolic rate and response to obesity in laboratory mice
Corrigan, J. K., Ramachandran, D., He, Y., Palmer, C., Jurczak, M. J., Li, B., Friedline, R. H., Kim, J. K., Ramsey, J. J., Lantier, L., McGuinness, O. P., Banks, A. S., Mouse Metabolic Phenotyping Center Energy Balance Working Group
10.1101/839076 — Posted: 2019-11-12
Accelerating functional gene discovery in osteoarthritis
Butterfield, N. C., Curry, K. F., Steinberg, J., Dewhurst, H., Komla-Ebri, D., Mannan, N. S., Adoum, A.-T., Leitch, V. D., Logan, J. G., Waung, J. A., Ghirardello, E., Southam, L., Youlten, S. E., Wilkinson, J. M., McAninch, E. A., Vancollie, V. E., Kussy, F., White, J. K., Adams, D. J., Lelliott, C. J., Jacques, R., Bianco, A. C., Boyde, A., Zeggini, E., Croucher, P. I., Williams, G. R., Bassett, J. H. D.
10.1101/836221 — Posted: 2019-11-10
Induction of pancreatic tumor-selective ferroptosis through modulation of cystine import
Badgley, M. A., Kremer, D., Maurer, H. C., DelGiorno, K. E., Lee, H.-J., Purohit, V., Sagalovskiy, I., Ma, A., Kapillian, J., Firl, C. E. M., Decker, A. R., Sastra, S. A., Palermo, C. F., Andrade, L. R., Sajjakulnukit, P., Zhang, L., Tolstyka, Z. P., Hirschhorn, T., Lamb, C., Liu, T., Gu, W., Seeley, E. S., Stone, E., Georgiou, G., Manor, U., Iuga, A., Wahl, G. M., Stockwell, B. R., Lyssiotis, C. A., Olive, K. P.
10.1101/827972 — Posted: 2019-11-01
ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair
Wells, D., Bitoun, E., Moralli, D., Zhang, G., Hinch, A. G., Donnelly, P., Green, C., Myers, S. R.
10.1101/821678 — Posted: 2019-10-30
Dual Histone Methyl Reader ZCWPW1 Facilitates Repair of Meiotic Double Strand Breaks
Mahgoub, M., Paiano, J., Bruno, M., Wu, W., Pathuri, S., Zhang, X., Ralls, S., Cheng, X., Nussenzweig, A., Macfarlan, T.
10.1101/821603 — Posted: 2019-10-29
Identification of a core module for bone mineral density through the integration of a co-expression network and GWAS data
Sabik, O. L., Calabrese, G. M., Taleghani, E., Ackert-Bicknell, C. L., Farber, C. R.
10.1101/803197 — Posted: 2019-10-13
HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases
Jordan, D. M., Verbanck, M., Do, R.
10.1101/311332 — Posted: 2019-10-07
Next generation sequencing reveals NRAP as a candidate gene for hypertrophic cardiomyopathy in elderly patients
Sharma, A., Koranchery, R., Rajendran, R., Mohanan, K. S., Shenthar, J., Perundurai, D. S.
10.1101/789065 — Posted: 2019-10-02

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