COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,903 Articles (22,568 medRxiv, 8,335 bioRxiv)

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SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
Huang, J., Hume, A. J., Abo, K. M., Werder, R. B., Villacorta-Martin, C., Alysandratos, K. D., Beermann, M. L., Simone-Roach, C., Olejnik, J., Suder, E., Bullitt, E., Hinds, A., Sharma, A., Bosmann, M., Wang, R., Hawkins, F., Burks, E. J., Saeed, M., Wilson, A. A., Mühlberger, E., Kotton, D. N.
10.1101/2020.06.30.175695 — Posted: 2020-06-30
Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
Xu, C., Wang, Y., Liu, C., Zhang, C., Han, W., Hong, X., Wang, Y., Hong, Q., Wang, S., Zhao, Q., Wang, Y., Yang, Y., Chen, K., Zheng, W., Kong, L., Wang, F., Zuo, Q., Huang, Z., Cong, Y.
10.1101/2020.06.30.177097 — Posted: 2020-06-30
Development of RNA-based assay for rapid detection of SARS-CoV-2 in clinical samples
Kumar, V., Mishra, S., Sharma, R., Agarwal, J., Ghoshal, U., Khanna, T., Sharma, L. K., Verma, S. K., Tiwari, S.
10.1101/2020.06.30.172833 — Posted: 2020-06-30 Discussion: Onsite
Validation and Comparison of a Modified CDC Assay with two Commercially Available Assays for the Detection of SARS-CoV-2 in Respiratory Specimen
Lima, A., Healer, V., Vendrone, E., Silbert, S.
10.1101/2020.06.29.179192 — Posted: 2020-06-30
SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 elicits immunogenicity in baboons and protection in mice
Tian, J.-H., Patel, N., Haupt, R., Zhou, H., Weston, S., Hammond, H., Lague, J., Portnoff, A. D., Norton, J., Guebre-Xabier, M., Zhou, B., Jacobson, K., Maciejewski, S., Khatoon, R., Wisniewska, M., Mottitt, W., Kluepfel-Stahl, S., Ekechukwu, B., Papin, J., Boddapati, S., Wong, C. J., Piedra, P. A., Frieman, M. B., Massare, M. J., Fries, L., Lovgren Bengtsson, K., Stertman, L., Ellingsworth, L. R., Glenn, G., Smith, G.
10.1101/2020.06.29.178509 — Posted: 2020-06-30 Discussion: Onsite
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies
Acharya, P., Williams, W., Henderson, R., Janowska, K., Manne, K., Parks, R., Deyton, M., Sprenz, J., Stalls, V., Kopp, M., Mansouri, K., Edwards, R. J., Meyerhoff, R., Oguin, T., Sempowski, G., Saunders, K. O., Haynes, B. F.
10.1101/2020.06.30.178897 — Posted: 2020-06-30
Genetic variants in TMPRSS2 and Structure of SARS-CoV-2 spike glycoprotein and TMPRSS2 complex
Vishnubhotla, R., Vankadari, N., Ketavarapu, V., Amanchy, R., Avanthi, S., Bale, G., Nageshwar Reddy, D., Sasikala, M.
10.1101/2020.06.30.179663 — Posted: 2020-06-30 Discussion: Onsite
Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
Mou, H., Quinlan, B., Peng, H., Guo, Y., Peng, S., Zhang, L., Davis-Gardner, M., Gardner, M., Voo, Z. X., Bailey, C. C., Alpert, M., Rader, C., Choe, H., Farzan, M.
10.1101/2020.06.29.178459 — Posted: 2020-06-30
Single-cell transcriptional atlas of the Chinese horseshoe bat (Rhinolophus sinicus) provides insight into the cellular mechanisms which enable bats to be viral reservoirs
Ren, L., Wu, C., Guo, L., Yao, J., Wang, C., Xiao, Y., Pisco, A. O., Wu, Z., Lei, X., Liu, Y., Shi, L., Han, L., Zhang, H., Xiao, X., Zhong, J., Wu, H., Li, M., Quake, S. R., Huang, Y., Wang, J., wang, j.
10.1101/2020.06.30.175778 — Posted: 2020-06-30 Discussion: Onsite | Offsite
A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection
Herrmann, A., Maruyama, J., Yue, C., Lahtz, C., Zhou, H., Kerwin, L., Guo, W., Zhang, Y., Soo Hoo, W., Yei, S., Kwon, S., Fu, Y., Johnson, S., Ledesma, A., Zhuang, Y., Zhuang, Y., Yei, E., Adamus, T., Praessler, S., Ji, H.
10.1101/2020.06.29.178616 — Posted: 2020-06-30 Discussion: Offsite

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).