Channel:  Harvard Program in Therapeutic Sciences

114 Articles

Prophage-encoded phage defence proteins with cognate self-immunity
Owen, S. V., Wenner, N., Dulberger, C. L., Rodwell, E. V., Bowers-Barnard, A., Quinones-Olvera, N., Rigden, D. J., Rubin, E. J., Garner, E. C., Baym, M., Hinton, J. C. D.
10.1101/2020.07.13.199331 — Posted: 2021-02-19
Systematic measurement of combination drug landscapes to predict in vivo treatment outcomes for tuberculosis
Larkins-Ford, J., Greenstein, T., Van, N., Degefu, Y. N., Olson, M. C., Sokolov, A., Aldridge, B. B.
10.1101/2021.02.03.429579 — Posted: 2021-02-06
Proteomic profiling of breast cancer cell lines and models
Kalocsay, M., Berberich, M., Everley, R., Nariya, M., Chung, M., Gaudio, B., Victor, C., Bradshaw, G., Hafner, M., Sorger, P. K., Mills, C., Subramanian, K.
10.1101/2020.12.15.422823 — Posted: 2020-12-15
Three-dimensional spatial transcriptomics uncovers cell type dynamics in the rheumatoid arthritis synovium
Vickovic, S., Schapiro, D., Carlberg, K., Loetstedt, B., Larsson, L., Korotkova, M., Hensvold, A. H., Catrina, A. I., Sorger, P. K., Malmstroem, V., Regev, A., Stahl, P. L.
10.1101/2020.12.10.420463 — Posted: 2020-12-11
Multiplexed proteomics and imaging of resolving and lethal SARS-CoV-2 infection in the lung
Kalocsay, M., Maliga, Z., Nirmal, A. J., Eisert, R. J., Bradshaw, G. A., Solomon, I. H., Chen, Y.-A., Pelletier, R. J., Jacobson, C. A., Mintseris, J., Padera, R. F., Martinot, A. J., Barouch, D. H., Santagata, S., Sorger, P.
10.1101/2020.10.14.339952 — Posted: 2020-10-15
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity
Inde, Z., Yapp, C., Joshi, G. N., Spetz, J., Fraser, C., Deskin, B., Ghelfi, E., Sodhi, C., Hackam, D., Kobzik, L., Croker, B., Brownfield, D., Jia, H., Sarosiek, K. A.
10.1101/2020.09.13.276923 — Posted: 2020-09-13
Online narrative guides for illuminating tissue atlas data and digital pathology images
Rashid, R., Chen, Y.-A., Hoffer, J., Muhlich, J. L., Lin, J.-R., Krueger, R., Pfister, H., Mitchell, R., Santagata, S., Sorger, P.
10.1101/2020.03.27.001834 — Posted: 2020-08-19
Time-resolved proteomic profiling of the ciliary Hedgehog response reveals that GPR161 and PKA undergo regulated co-exit from cilia
May, E. A., Kalocsay, M., Galtier D'Auriac, I., Gygi, S. P., Nachury, M. V., Mick, D. U.
10.1101/2020.07.29.225797 — Posted: 2020-07-29
Simplitigs as an efficient and scalable representation of de Bruijn graphs
Brinda, K., Baym, M., Kucherov, G.
10.1101/2020.01.12.903443 — Posted: 2020-06-21
Orphan nuclear receptor COUP-TFII drives the myofibroblast metabolic shift leading to fibrosis
Li, L., Galichon, P., Xiao, X., Figueroa-Ramirez, A. C., Tamayo, D., Lee, J. J., Kalocsay, M., Gonzalez-Sanchez, D., Chancay, M. S., McCracken, K., Lemos, D., Lee, N., Ichimura, T., Mori, Y., Valerius, M. T., Sun, X., Edelman, E. R., Bonventre, J. V.
10.1101/2020.06.05.135889 — Posted: 2020-06-05

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