Channel: University of Massachusetts Chan Medical School

This collection includes bioRxiv and medRxiv papers from authors at University of Massachusetts Chan Medical School .

1006 Articles

An integrated view of the structure and function of the human 4D nucleome

The 4D Nucleome Consortium, , Dekker, J., Oksuz, B. A., Zhang, Y., Wang, Y., Minsk, M. K., Kuang, S., Yang, L., Gibcus, J. H., Krietenstein, N., Rando, O., Xu, J., Janssens, D. H., Henikoff, S., Kukalev, A., Willemin, A., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M., Kumar, P., Zhang, L., Belmont, A. S., Sasaki, T., van Schaik, T., Brueckner, L., Peric-Hupkes, D., van Steensel, B., Wang, P., Chai, H., Kim, M., Ruan, Y., Zhang, R., Quinodoz, S. A., Bhat, P., Guttman, M., Zhao, W., Chien, S., Liu, Y., Venev, S. V., Plewczynski, D., Irastorza Azcarate, I., Szabo, D., Thieme, C. J., Szczepinska

10.1101/2024.09.17.613111 — Posted: 2024-10-27

Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography

Huang, Q. Y., Kim, R., Song, K., Grigorieff, N., Munro, J., Schiffer, C. A., Somasundaran, M.

10.1101/2024.10.15.618557 — Posted: 2024-10-18

The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization

Gramatica, A., Miller, I. G., Ward, A. R., Khan, F., Kemmer, T. J., Weiler, J., Huynh, T. T., Zumbo, P., Kurland, A. P., Leyre, L., Ren, Y., Klevorn, T., Copertino, D. C., Chukwukere, U., Levinger, C., Dilling, T. R., Linden, N. L., Board, N. L., Falling Iversen, E., Terry, S., Mota, T. M., Bedir, S., Clayton, K. L., Bosque, A., MacLaren Ehui, L., Kovacs, C. M., Betel, D., Johnson, J. R., Paiardini, M., Danesh, A., Jones, R. B.

10.1101/2024.10.11.617869 — Posted: 2024-10-15

Comet fragment-ion indexing for enhanced peptide sequencing

McGann, C. D., Bergstrom, E. J., Sharma, V., Heil, L. R., Yu, Q., Eng, J. K., Schweppe, D. K.

10.1101/2024.10.11.617953 — Posted: 2024-10-15

Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction.

Grace, P. S., Peters, J. M., Sixsmith, J., Lu, R., Fenderson, B. A., Vickers, A., Slein, M. D., Irvine, E. B., McKitrick, T., Wei, M.-H., Cummings, R. D., Wallace, A., Cavacini, L., Choudhary, A. K., Proulx, M. K., Sundling, C., Källenius, G., Reljic, R., Ernst, J. D., Casadevall, A., Locht, C., Pinter, A., Sassetti, C. M., Bryson, B. D., Fortune, S. M., Alter, G.

10.1101/2024.10.07.617070 — Posted: 2024-10-11

Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

Simwela, N. V., Jaecklein, E., Sassetti, C. M., Russell, D. G. M.

10.1101/2024.07.22.604660 — Posted: 2024-10-11

Antisense oligonucleotide targeting pathogenic sense repeat RNA in C9ORF72 suppresses production of antisense-dependent dipeptide repeat proteins implicated in ALS/FTD

Gu, Y., Kankel, M. W., Watts, J., Jafar-nejad, P., Almeida, S.

10.1101/2024.10.04.616663 — Posted: 2024-10-05

Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate neutrophilic allergic airways disease.

Ravi, V. R., Korkmaz, F. T., Lyon De Ana, C., Lu, L., Shao, F.-Z., Odom, C. V., Barker, K. A., Ramanujan, A., Niszczak, E. N., Goltry, W. N., Martin, I. M. C., Ha, C. T., Quinton, L. J., Jones, M. R., Fine, A., Welch, J. D., Chen, F., Belkina, A. C., Mizgerd, J. P., Shenoy, A. T.

10.1101/2024.10.03.616494 — Posted: 2024-10-04

Transcriptome-based identification of long noncoding RNAs (lncRNAs) across the genome of Anopheles gambiae

Xu, J., Hu, K., Riehle, M. M., Khadka, V.

10.1101/2024.10.02.616138 — Posted: 2024-10-03

Real-Time Spatiotemporal Tracking of Infectious Outbreaks in Confined Environments with a Host-Pathogen Agent-Based System

Srinivasan, S., King, J., Colubri, A., Korkin, D.

10.1101/2024.10.01.616085 — Posted: 2024-10-03

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