Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4259 Articles

Polymorphic tandem repeats shape single-cell gene expression across the immune landscape

Tanudisastro, H. A., Cuomo, A. S. E., Weisburd, B., Welland, M., Spenceley, E., Franklin, M., Xue, A., Bowen, B., Wing, K., Tang, O., Gray, M., Reis, A. L. M., Margoliash, J., Kurtas, E. N., Pullin, J., Lee, A. S., Brand, H., Harper, M., Bobowik, K., Silk, M., Marshall, J., Bakiris, V., Swapna Madala, B., Uren, C., Bartie, C., Senabouth, A., Dashnow, H., Fearnley, L., Dolzhenko, E., Qiao, Z., Grieve, S., Nguyen, T., Talkowski, M., Alexander, S. I., Siggs, O. M., Gruenschloss, L., Nicholas, H. R., Piscionere, J., Simons, C., Wallace, C., Gymrek, M., Deveson, I. W., Hewitt, A. W., Figtree, G. A.

10.1101/2024.11.02.621562 — Posted: 2024-11-04

A PERTURBATION CELL ATLAS OF HUMAN INDUCED PLURIPOTENT STEM CELLS

Nourreddine, S., Doctor, Y., Dailamy, A., Forget, A., Lee, Y.-H., Chinn, B., Khaliq, H., Polacco, B., Muralidharan, M., Pan, E., Zhang, Y., Sigaeva, A., Hansen, J. N., Gao, J., Parker, J. A., Obernier, K., Clark, T., Chen, J. Y., Metallo, C., Lundberg, E., Ideker, T., Krogan, N., Mali, P.

10.1101/2024.11.03.621734 — Posted: 2024-11-04

F2,6BP restores mitochondrial genome integrity in Huntingtons Disease

Chakraborty, A., Mandal, S. M., Mankevich, M., Sreenivasmurthy, S. G., Hegde, M., Ghosh, G., Hazra, T.

10.1101/2024.11.04.621834 — Posted: 2024-11-04

Clinical syndromes linked to biallelic germline variants in MCM8 and MCM9

Helderman, N. C., Yang, T., Palles, C., Terlouw, D., Mei, H., Vorderman, R. H. P., Cats, D., Diaz Gay, M., Jongmans, M. C. J., Ramdien, A., van de Beek, I., Eleveld, T. F., Green, A., Hes, F. J., van den Heuvel-Eibrink, M. M., Van Der Kelen, A., Kliesch, S., Kuiper, R. P., Lakeman, I. M. M., Lashley, L. E. E. L. O., Looijenga, L. H. J., Oud, M. S., Steingröver, J., Tenenbaum-Rakover, Y., Tops, C. M., Tüttelmann, F., de Voer, R. M., Westra, D., Wyrwoll, M. J., Golubicki, M., Antelo, M., Bonjoch, L., Terradas, M., Valle, L., Alexandrov, L. B., Morreau, H., van Wezel, T., Castellvi-Bel, S., Gol

10.1101/2024.10.30.24315828 — Posted: 2024-11-04

From a genomic risk model to clinical trial implementation in a learning health system: the ProGRESS Study

Vassy, J. L., Dornisch, A. M., Karunamuni, R., Gatzen, M., Kachulis, C. J., Lennon, N. J., Brunette, C. A., Danowski, M. E., Hauger, R. L., Garraway, I. P., Kibel, A. S., Lee, K. M., Lynch, J. A., Maxwell, K. N., Rose, B. S., Teerlink, C. C., Xu, G. J., Hofherr, S. E., Lafferty, K. A., Larkin, K., Malolepsza, E., Patterson, C. J., Toledo, D. M., Donovan, J. L., Hamdy, F., Martin, R. M., Neal, D. E., Turner, E. L., Andreassen, O. A., Dale, A. M., Mills, I. G., Batra, J., Clements, J., Cussenot, O., Cybulski, C., Eeles, R. A., Fowke, J. H., Grindedal, E. M., Hamilton, R. J., Lim, J., Lu, Y.-J.

10.1101/2024.11.03.24316516 — Posted: 2024-11-04

Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability

Sannigrahi, M. K., Raghav, L., Rich, D. J., Schrank, T. P., Califano, J. A., Lukens, J. N., Sun, L., Morgan, I. M., Cohen, R. B., Lin, A., Liu, X., Brown, E. J., You, J., Mirabello, L., Mishra, S. K., Shimunov, D., Brody, R. M., Pearson, A. T., Gimotty, P. A., Diab, A., Jalaly, J. B., Basu, D.

10.1101/2024.10.31.621311 — Posted: 2024-11-04

Synaptic cleft geometry modulates NMDAR opening probability by tuning neurotransmitter residence time

Hernandez Mesa, M., McCabe, K., Rangamani, P.

10.1101/2024.10.30.621190 — Posted: 2024-11-03

The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds

Mannochio-Russo, H., Charron-Lamoureux, V., van Faassen, M., Lamichhane, S., Goncalves Nunes, W. D., Deleray, V., Patan, A., Vittali, K., Rajkumar, P., El Abiead, Y., Zhao, H. N., Portal Gomes, P. W., Mohanty, I., Lee, C., Sund, A., Sharma, M., Liu, Y., Pattynama, D., Walker, G. T., Norton, G. J., Khatib, L., Andalibi, M. S., Wang, C. X., Ellis, R. J., Moore, D. J., Iudicello, J. E., Franklin, D., Letendre, S., Chin, L., Walker, C., Renwick, S., Zemlin, J., Meehan, M. J., Song, X., Kasper, D., Burcham, Z., Kim, J. J., Kadakia, S., Raffatellu, M., Bode, L., Zengler, K., Wang, M., Siegel, D., Kn

10.1101/2024.10.31.621412 — Posted: 2024-11-03

To impute or not to impute in untargeted metabolomics - that is the compositional question

Krutkin, D. D., Thomas, S., Zuffa, S., Rajkumar, P., Knight, R., Dorrestein, P. C., Kelley, S. T.

10.1101/2024.10.28.620738 — Posted: 2024-11-02

Community Health Worker Outreach to Assess Confounders of Health

Takallou, A. B., Mitchell, E., Richardson, G. M., Frank, B.

10.1101/2024.10.31.24316456 — Posted: 2024-11-02

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