Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4726 Articles

EXPRESSION OF A SECRETABLE, CELL-PENETRATING CDKL5 PROTEIN ENHANCES THE EFFICACY OF AAV VECTOR-MEDIATED GENE THERAPY FOR CDKL5 DEFICIENCY DISORDER.

Medici, G., Tassinari, M., Galvani, G., Bastianini, S., Gennaccaro, L., Loi, M., Mottolese, N., Alvente, S., Berteotti, C., Sagona, G., Lupori, L., Bagget, H. R., Zoccoli, G., Giustetto, M., Muotri, A. R., Pizzorusso, T., Nakai, H., Trazzi, S., Ciani, E.

10.1101/2021.07.26.453746 — Posted: 2021-12-17

A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila

Lopez del Amo, V., Sanz Juste, S., Gantz, V. M.

10.1101/2021.12.01.470847 — Posted: 2021-12-17

A practical guide for generating unsupervised, spectrogram-based latent space representations of animal vocalizations

Thomas, M., Jensen, F., Averly, B., Demartsev, V., Manser, M. B., Sainburg, T., Roch, M., Strandburg-Peshkin, A.

10.1101/2021.12.16.472881 — Posted: 2021-12-17

Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy

Liu, M., Hernandez-Morales, A. C., Clark, J., Le, T. T., Biswas, B., Bishop-Lilly, K. A., Henry, M. S., Quinones, J., Hamilton, T., Schooley, R., Salka, S., Young, R. F., Gill, J. J.

10.1101/2021.12.14.472731 — Posted: 2021-12-16

Pathogenesis of Alzheimer's disease: Involvement of the Choroid Plexus

Carna, M., Onyango, I. G., Katina, S., Holub, D., Nezvezdova, M., Jha, D., Nedelska, Z., Lacovich, V., Vyvere, T. V., Houbrechts, R., Garcia-Mansfield, K., Sharma, R., David-Dirgo, V., Vyhnalek, M., Texlova, K., Chaves, H., Bakkar, N., Pertierra, L., Vinkler, M., Markova, H., Laczo, J., Sheardova, K., Fric, J., Forte, G., Kanovsky, P., Belaskova, S., Damborsky, J., Hort, J., Seyfried, N. T., Bowser, R., Sevlever, G., Rissman, R. A., Smith, R. A., Hajduch, M., Pirrotte, P., Spacil, Z., Dammer, E. B., Limbaeck Stokin, C., Stokin, G. B.

10.1101/2021.07.29.21260696 — Posted: 2021-12-16

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain

Kember, R. L., Vickers-Smith, R. A., Xu, H., Toikumo, S., Niarchou, M., Zhou, H., Hartwell, E. E., Crist, R. C., Rentsch, C. T., VA Million Veteran Program, , Davis, L. K., Justice, A. C., Sanchez-Roige, S., Kampman, K. M., Gelernter, J., Kranzler, H.

10.1101/2021.12.13.21267480 — Posted: 2021-12-15

Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry.

Deak, J. D., Zhou, H., Galimberti, M., Levey, D. F., Wendt, F. R., Sanchez-Roige, S., Hatoum, A. S., Johnson, E. C., Nunez, Y. Z., Demontis, D., Borglum, A. D., Rajagopal, V. M., Jennings, M. V., Kember, R. L., Justice, A. C., Edenberg, H. J., Agrawal, A., Polimanti, R., Kranzler, H. R., Gelernter, J.

10.1101/2021.12.04.21267094 — Posted: 2021-12-15

Randomized controlled trial transfusing convalescent plasma as post-exposure prophylaxis against SARS-CoV-2 infection

Shoham, S., Bloch, E. M., Casadevall, A., Hanley, D., Lau, B., Gebo, K., Cachay, E., Kassaye, S. G., Paxton, J. H., Gerber, J., Levine, A. C., Currier, J., Patel, B., Allen, E. S., Anjan, S., Appel, L., Baksh, S., Blair, P. W., Bowen, A., Broderick, P., Caputo, C. A., Cluzet, V., Cordisco, M. E., Cruser, D., Ehrhardt, S., Forthal, D., Fukuta, Y., Gawad, A., Gniadek, T., Hammel, J., Huaman, M. A., Jabs, D. A., Jedlicka, A., Karlen, N., Klein, S., Laeyendecker, O., Lane, K., McBee, N., Meisenberg, B., Merlo, C., Mosnaim, G., Park, H.-S., Pekosz, A., Petrini, J., Rausch, W., Shade, D. M., Shapiro

10.1101/2021.12.13.21267611 — Posted: 2021-12-14

An intestinally secreted host factor promotes microsporidia invasion of C. elegans

El Jarkass, H. T., Mok, C., Schertzberg, M. R., Fraser, A. G., Troemel, E. R., Reinke, A. W.

10.1101/2021.07.12.452088 — Posted: 2021-12-13

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

Biering, S. B., Tramontini Gomes de Sousa, F., Tjang, L. V., Pahmeier, F., Ruan, R., Blanc, S. F., Patel, T. S., Worthington, C. M., Glasner, D. R., Castillo-Rojas, B., Servellita, V., Lo, N. T., Wong, M. P., Warnes, C. M., Sandoval, D. R., Clausen, T. M., Santos, Y. A., Ortega, V., Aguilar-Carreno, H., Esko, J. D., Chiu, C. Y., Pak, J. E., Beatty, P. R., Harris, E.

10.1101/2021.12.10.472112 — Posted: 2021-12-13

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