Channel: University of California, San Diego

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Diego.

4599 Articles

Evaluating a Genome-Wide Polygenic Score for Handgrip Strength and Its Interplay with Leisure-Time Physical Activity Across the IGEMS Twin Cohorts

Herranen, P., Palviainen, T., Nygaard, M., Karlsson, I. K., Thalamuthu, A., Mather, K. A., Reynolds, C. A., Panizzon, M. S., Rantanen, T., Finkel, D., Gatz, M., Pedersen, N. L., IGEMS Consortium, , Kaprio, J., Sillanpää, E.

10.1101/2025.08.07.25333195 — Posted: 2025-08-15

Epigenetic motifs distinguishing endogenous from exogenous retroviral integrants

LaMere, S., Xiong, H., Wang, W., LaMere, B., Moshiri, N.

10.1101/2025.04.30.651506 — Posted: 2025-08-14

A population-scale atlas of blood and tissue in lupus nephritis

Gurajala, S., Sugiarto, N. W., Curtis, M., Eisenhaure, T. M., Arazi, A., Fava, A., Xiao, Q., Mears, J., Rovin, B., Berthier, C. C., Izmirly, P. M., Barnas, J. L., Hoover, P. J., Peters, M., Raychowdhury, R., Horisberger, A., Sakaue, S., Zhao, Y., Furie, R. A., Belmont, H. M., Hildeman, D. A., Woodle, E. S., Dall'Era, M., Putterman, C., Kamen, D. L., McMahon, M. A., Grossman, J., Kalunian, K. C., Hodgin, J. B., Payan-Schober, F., Apruzzese, W., Perlman, H., Cuda, C. M., Wofsy, D., Guthridge, J. M., Anolik, J. H., James, J. A., Accelerating Medicines Partnerships Rheumatoid Arthritis/Systemic Lu

10.1101/2025.08.11.669754 — Posted: 2025-08-14

Recombinant proteasome provides new avenues for anti-malarial drug development.

Fajtova, P., Zhang, H., Urich, L., da Silva, E. B., da Silva, C. H., Almaliti, J., Al-Hindy, M., Boura, E., Fidock, D. A., Kirkman, L., Lin, G., Bogyo, M., Gerwick, W. H., Zhao, J., O'Donoghue, A. J.

10.1101/2025.08.13.670186 — Posted: 2025-08-14

Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence

Du, X., Tseng, C.-W., Bjanes, E., Gage, H., Swan, J., Tsai, C. M., Hajam, I., Gonzalez, C., Lin, B., Nizet, V., Liu, G. Y.

10.1101/2025.08.14.670416 — Posted: 2025-08-14

Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease

Zhang, B., McEvoy, L. K., Nguyen, S., Espeland, M. A., Rapp, S. R., Horvath, S., Lu, A., LaCroix, A. Z., Nievergelt, C. M., Maihofer, A. X., Resnick, S. M., Mielke, M. M. M., Beckman, K. B., Li, D., Silver, B., Manson, J. E., Ferrucci, L., Shadyab, A. H.

10.1101/2025.08.12.25333453 — Posted: 2025-08-14

Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine

Gutierrez, M. d. l. P., Hall, J. L., Winter, S. E., Rivera-Chavez, F.

10.1101/2025.08.12.669941 — Posted: 2025-08-14

Commensal taxa in gut microbiota limit antibiotic resistance during extended oral antibiotic use

Cyphert, E. L., Liu, C., Chu, V. T., Dubey, A., Liu, M., Zhong, Z., Cockey, J. R., Diaz, E. C. G., Morales, A. L., Nixon, J. C., Garcia, M., Zeng, S., Rohatgi, S., Wong, J., Arjyal, R., Mekonen, H., Neff, N., Lee, J., Shea, M. K., Fu, X., Booth, S. L., Leifer, C. A., Singh, A., Langelier, C. R., Hernandez, C. J.

10.1101/2025.08.13.670183 — Posted: 2025-08-13

Glycopolymers stabilize protein folding and protein-protein interactions via enthalpic interactions

Richter, S. M., Brook, N., Guseman, A.

10.1101/2025.08.11.669795 — Posted: 2025-08-13

The Establishment of Cell-Type Specific Gene Regulation in the Sea Urchin Embryo

Brandenburg, J. M., Trinks, A., Vojtasova, D., Monaco, A. A., Arsie, R., Hu, M., Hamdoun, A., Jenniches, C., Landthaler, M., Bluthgen, N., Garfield, D.

10.1101/2025.08.12.669999 — Posted: 2025-08-13

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