Channel: Albert Einstein College of Medicine

This collection includes bioRxiv and medRxiv papers from authors at Albert Einstein College of Medicine.

906 Articles

Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma

Kadamb, R., Anton, M. L., Purwin, T. J., Chua, V., Seeneevassen, L., Teh, J., Nieto, M. A., Sato, T., Terai, M., Roman, S., de Koning, L., Zheng, D., Aplin, A. E., Aguirre-Ghiso, J.

10.1101/2024.03.05.583565 — Posted: 2024-03-08

The expected polygenic risk score (ePRS) framework: an equitable metric for quantifying polygenetic risk via modeling of ancestral makeup

Huang, Y.-J., Kurniansyah, N., Goodman, M. O., Spitzer, B. W., Wang, J., Stilp, A. M., Laurie, C., de Vries, P. S., Chen, H., Min, Y.-I., Sims, M., Peloso, G. M., Guo, X., Bis, J. C., Brody, J. A., Raffield, L. M., Smith, J. A., Zhao, W., Rotter, J. I., Rich, S. S., Redline, S., Fornage, M., Kaplan, R., Franceschini, N., Levy, D., Morrison, A. C., Boerwinkle, E., Smith, N. L., Kooperberg, C., Psaty, B. M., Zoellner, S., Sofer, T.

10.1101/2024.03.05.24303738 — Posted: 2024-03-06

Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38

Shin, O. S., Monticelli, S. R., Hjorth, C. K., Hornet, V., Doyle, M., Abelson, D., Kuehne, A. I., Wang, A., Bakken, R. R., Mishra, A. K., Middlecamp, M., Champney, E., Stuart, L., Maurer, D. P., Li, J., Berrigan, J. L., Balinandi, S., Lutwama, J. J., Lobel, L., Zeitlin, L., Walker, L. M., Dye, J. M., Chandran, K., Herbert, A. S., Pauli, N. T., McLellan, J. S.

10.1101/2024.03.02.583110 — Posted: 2024-03-06

Damage sensing through TLR9 Promotes Viral Clearance and Recovery During Influenza Infection

Kim, J., Yuan, Y., Agaronyan, K., Zhao, A., Wang, V. D., Gupta, G., Essayas, H., Kaminski, A., McGovern, J., Yu, S., Woo, S., Lee, C. J., Saleh, T., Hu, B., Sun, Y., Ishikawa, G., Bain, W., Evankovich, J., Herzog, E., Dela Cruz, C. S., Ryu, C., Sharma, L.

10.1101/2024.03.04.583378 — Posted: 2024-03-06

The MLL3/TP53/PIK3CA cancer driver mutations promote HIF1alpha-dependent recruitment and differentiation of pro-tumor ICOShiGITRhi Blimp-1+ effector regulatory T cells in breast tumors

Boutet, M., Nishitani, K., Erler, P., Couturier, N., Zhang, Z., Barbieux, E., Guillen, E., Suzuki, M., Guo, W., Lauvau, G.

10.1101/2022.10.02.510540 — Posted: 2024-03-03

Ultrastructural analysis reveals mitochondrial placement independent of synapse placement in fine caliber C. elegans neurons

Riboul, D. V., Crill, S., Oliva, C. D., Restifo, M. G., Joseph, R., Joseph, K., Nguyen, K. C., Hall, D. H., Fily, Y., Macleod, G. T.

10.1101/2023.05.30.542959 — Posted: 2024-03-02

Lens Placode Modulates Extracellular Matrix Formation During Early Eye Development

de Magalhaes, C. G., Cvekl, A., Jaeger, R. G., Yan, C. Y. I.

10.1101/2023.11.30.569417 — Posted: 2024-02-28

Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia

Bonifazi, A., Ellenberger, M., Farino, Z. J., Aslanoglou, D., Rais, R., Pereira, S., Mantilla-Rivas, J. O., Boateng, C. A., Eshleman, A. J., Janowsky, A., Hahn, M. K., Schwartz, G. J., Slusher, B. S., Newman, A. H., Freyberg, Z.

10.1101/2024.02.21.581451 — Posted: 2024-02-24

Ultrarare Variants in DNA Damage Repair Genes in Pediatric Acute-Onset Neuropsychiatric Syndrome or Acute Behavioral Regression in Neurodevelopmental Disorders

Cunningham, J. L., Frankovich, J., Dubin, R. A., Pedrosa, E., Nur Baykara, R., Schlenk, N. C., Maqbool, S., Dolstra, H., Marino, J., Edinger, J., Shea, J., Laje, G., Swagermakers, S. M. A., Sinnadurai, S., van der Spek, P., Lachman, H. M.

10.1101/2024.02.20.24302984 — Posted: 2024-02-23

Maternal Immune Activation Alters Temporal Precision of Spike Generation of CA1 Pyramidal Neurons by Unbalancing GABAergic Inhibition in the Offspring

Griego, E., Cerna, C., Sollozo-Dupont, I., Fuenzalida, M., Galvan, E. J.

10.1101/2024.02.19.581109 — Posted: 2024-02-22

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