Channel: University of California, San Francisco

This collection includes bioRxiv and medRxiv papers from authors at University of California, San Francisco.

2401 Articles

Multi-center integrated analysis of non-coding CRISPR screens

Yao, D., Tycko, J., Oh, W., Bounds, L. R., Gosai, S. J., Lataniotis, L., Mackay-Smith, A., Doughty, B. R., Gabdank, I., Schmidt, H., Youngworth, I., Andreeva, K., Ren, X., Barrera, A., Luo, Y., Siklenka, K., Yardimci, G. G., The ENCODE4 Consortium, , Tewhey, R., Kundaje, A., Greenleaf, W. J., Sabeti, P. C., Leslie, C., Pritykin, Y., Moore, J. E., Beer, M. A., Gersbach, C., Reddy, T. E., Shen, Y., Engreitz, J. M., Bassik, M. C., Reilly, S. K.

10.1101/2022.12.21.520137 — Posted: 2022-12-22

A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling

Lawrence, R., Shoemaker, S., Deal, A., Sangwan, S., Anand, A., Wang, L., Marqusee, S., Walter, P.

10.1101/2022.12.22.521453 — Posted: 2022-12-22

Applying a computational transcriptomics-based drug repositioning pipeline to identify therapeutic candidates for endometriosis

Oskotsky, T. T., Bhoja, A., Bunis, D., Le, B. L., Kosti, I., Li, C., Houshdaran, S., Sen, S., Vallve-Juanico, J., Wang, W., Arthurs, E., Mahoney, L., Lang, L., Gaudilliere, B., Stevenson, D. K., Irwin, J. C., Giudice, L. C., McAllister, S., Sirota, M.

10.1101/2022.12.20.22283736 — Posted: 2022-12-21

O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors

Zhang, Z., Huang, Z., Awad, M., Elsalanty, M., Cray, J., Ball, L. E., Maynard, J., Burlingame, A. L., Zeng, H., Mansky, K. C., Ruan, H.-B.

10.1101/2022.12.21.521379 — Posted: 2022-12-21

Silencing neuroinflammatory reactive astrocyte activating factors ameliorates disease outcomes in perinatal white matter injury

Renz, P. V., Surbek, D., Haesler, V., Tscherrig, V., Huang, E. J., Chavali, M., Liddelow, S. A., Rowitch, D., Schoeberlein, A., Brosius Lutz, A. R.

10.1101/2022.12.19.521083 — Posted: 2022-12-20

Left-handedness, learning disability, autoimmune disease, and seizure history influence age at onset and phenotypical targeting of Alzheimer's disease

Miller, Z. A., Ossenkoppele, R., Graff-Radford, N. R., Allen, I. E., Shwe, W., Rosenberg, L., Olguin, D. J., Erkkinen, M. G., Butler, P. M., Spina, S., Yokoyama, J. S., Desikan, R. S., Scheltens, P., van der Flier, W., Pijnenburg, Y., Wolters, E., Rademakers, R., Geschwind, D. H., Kramer, J. H., Rosen, H. J., Rankin, K. P., Grinberg, L. T., Seeley, W. W., Sturm, V., Perry, D. C., Miller, B. L., Rabinovici, G. D., Gorno-Tempini, M. L.

10.1101/2022.12.17.22283307 — Posted: 2022-12-20

Structural basis of odorant recognition by a human odorant receptor

Billesboelle, C. B., de March, C. A., van der Velden, W. J. C., Ma, N., Tewari, J., Linas del Torrent, C., Li, L., Faust, B., Vaidehi, N., Matsunami, H., Manglik, A.

10.1101/2022.12.20.520951 — Posted: 2022-12-20

Young peoples data governance preferences for their mental health data: MindKind Study findings from India, South Africa, and the United Kingdom

Sieberts, S., Marten, C., Bampton, E., Björling, E. A., Burn, A.-M., Carey, E., Carlson, S., Fernandes, B., Kalha, J., Lindani, S., Masomera, H., Neelakantan, L., Pasquale, L., Ranganathan, S., Scanlan, J., Shah, H., Sibisi, R., Sumant, S., Suver, C., Thungana, Y., Tummalacherla, M., Velloza, J., Collins, P., Fazel, M., Ford, T., Freeman, M., Pathare, S., Zingela, Z., The MindKind Consortium, , Doerr, M.

10.1101/2022.12.19.22283679 — Posted: 2022-12-20

Multisite evaluation and validation of Optical Genome Mapping for prenatal genetic testing

Stevenson, R. E., Liu, J., Iqbal, A., DuPont, B., Sahajpal, N., Ho, M., Yu, J., Brody, S. J., Ganapathi, M., Rajkovic, A., Smolarek, T., Boyar, F. Z., Bui, P. H., Dubuc, A. M., Kolhe, R., Levy, B.

10.1101/2022.12.19.22283552 — Posted: 2022-12-20

Aberrant hierarchical prediction errors are associated with transition to psychosis: A computational single-trial analysis of the mismatch negativity

Hauke, D. J., Charlton, C. E., Schmidt, A., Griffiths, J., Woods, S. W., Ford, J. M., Srihari, V. H., Roth, V., Diaconescu, A. O., Mathalon, D. H.

10.1101/2022.12.20.22283712 — Posted: 2022-12-20

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