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157 Reviews — eLife — Genomics

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Multi-tissue landscape of somatic mtDNA mutations indicates tissue specific accumulation and removal in aging
Sanchez-Contreras, M., Sweetwyne, M. T., Tsantilas, K. A., Whitson, J. A., Campbell, M. D., Kohrn, B. F., Kim, H.-J., Fredrickson, J., Nguyen, M. M., Hurley, J. B., Marcinek, D. J., Rabinovitch, P. S., Kennedy, S. R.
10.1101/2022.08.30.505884 — Posted: 2022-09-01 — Discussion: 2023-02-10  eLife
Activity-based CRISPR Scanning Uncovers Allostery in DNA Methylation Maintenance Machinery
Ngan, K. C., Hoenig, S. M., Gosavi, P. M., Tanner, D. A., Lue, N. Z., Garcia, E. M., Lee, C., Liau, B. B.
10.1101/2022.05.14.491958 — Posted: 2022-05-15 — Discussion: 2023-01-02  eLife
Zooanthroponotic transmission of SARS-CoV-2 and host-specific viral mutations revealed by genome-wide phylogenetic analysis
Naderi, S., Chen, P., Murall, C. L., Poujol, R., Kraemer, S. A., Pickering, B. S., Sagan, S. M., Shapiro, B. J.
10.1101/2022.06.02.494559 — Posted: 2022-06-06 — Discussion: 2022-12-22  eLife
Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation
Landshammer, A., Bolondi, A., Kretzmer, H., Much, C., Buschow, R., Rose, A., Wu, H.-J., Mackowiak, S., Braendl, B., Giesselmann, P., Tornisiello, R., Parsi, K. M., Huey, J., Mielke, T., Meierhofer, D., Maehr, R., Hnisz, D., Michor, F., Rinn, J. L., Meissner, A.
10.1101/2022.09.12.507139 — Posted: 2022-09-13 — Discussion: 2022-12-16  eLife
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
Replogle, J. M., Bonnar, J. L., Pogson, A. N., Liem, C. R., Maier, N. K., Ding, Y., Russell, B. J., Wang, X., Leng, K., Guna, A., Norman, T. M., Pak, R. A., Ramos, D. M., Ward, M. E., Gilbert, L. A., Kampmann, M., Weissman, J. S., Jost, M.
10.1101/2022.07.13.499814 — Posted: 2022-07-13 — Discussion: 2022-12-08  eLife
Comprehensive re-analysis of hairpin RNAs in fungi reveals ancestral links
Johnson, N. R., Larrondo, L. F., Alvarez, J. M., Vidal, E. A.
10.1101/2022.09.15.508153 — Posted: 2022-09-16 — Discussion: 2022-11-28  eLife
Future COVID-19 surges prediction based on SARS-CoV-2 mutations surveillance
Najar, F., Linde, E., Murphy, C., Borin, V., Wang, H., Haider, S., Agarwal, P.
10.1101/2022.09.05.506640 — Posted: 2022-09-07 — Discussion: 2022-11-28  eLife
Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns
Soerensen, S. G., Shrikhande, A., Poulsgaard, G. A., Christensen, M. H., Bertl, J., Hoffmann, E. R., Pedersen, J. S.
10.1101/2022.01.31.478445 — Posted: 2022-02-03 — Discussion: 2022-11-18  eLife
Highly accurate isoform identification for the human transcriptome
Sommer, M. J., Cha, S., Varabyou, A., Rincon, N., Park, S., Minkin, I., Pertea, M., Steinegger, M., Salzberg, S.
10.1101/2022.06.08.495354 — Posted: 2022-06-09 — Discussion: 2022-10-31  eLife
Promoter sequence and architecture determine expression variability and confer robustness to genetic variants
Einarsson, H., Salvatore, M., Vaagenso, C., Alcaraz, N., Bornholdt Lange, J., Rennie, S., Andersson, R.
10.1101/2021.10.29.466407 — Posted: 2021-10-30 — Discussion: 2022-10-27  eLife

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