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169 Reviews — eLife — Genomics

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Non-linear transcriptional responses to gradual modulation of transcription factor dosage
Domingo, J., Minaeva, M., Morris, J. A., Ziosi, M., Sanjana, N. E., Lappalainen, T.
10.1101/2024.03.01.582837 — Posted: 2024-03-04 — Discussion: 2025-11-25  eLife
Heterogeneity of Genetic Sequence within Quasi-species of Influenza Virus Revealed by Single-Molecule Sequencing
Tamao, K., Noji, H., Tabata, K. V.
10.1101/2025.06.19.658006 — Posted: 2025-06-19 — Discussion: 2025-11-24  eLife
The genetic control of rapid genome content divergence in Arabidopsis thaliana
Fiscus, C. J., Koenig, D.
10.1101/2025.06.11.659220 — Posted: 2025-06-16 — Discussion: 2025-10-20  eLife
Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases
Jeong, R., Bulyk, M. L.
10.1101/2024.04.12.589213 — Posted: 2024-04-15 — Discussion: 2025-10-03  eLife
Genome reorganization and its functional impact during breast cancer progression
Reed, K. S. M., Fritz, A., Greenyer, H., Heselmeyer-Haddad, K., Frietze, S., Stein, J., Stein, G., Misteli, T.
10.1101/2025.05.14.654144 — Posted: 2025-05-17 — Discussion: 2025-09-10  eLife
OpenSpliceAI: An efficient, modular implementation of SpliceAI enabling easy retraining on non-human species
Chao, K.-H., Mao, A., Liu, A., Salzberg, S. L., Pertea, M.
10.1101/2025.03.20.644351 — Posted: 2025-03-23 — Discussion: 2025-09-09  eLife
Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations
Dillard, L. J., Calabrese, G. M., Mesner, L. D., Farber, C. R.
10.1101/2024.05.20.594981 — Posted: 2025-05-29 — Discussion: 2025-09-02  eLife
Human cytomegalovirus extensively re-organizes the human genome, diminishing TEAD1 transcription factor activity
Sayeed, K., Parameswaran, S., Beucler, M. J., Edsall, L. E., VonHandorf, A., Crowther, A., Donmez, O. A., Hass, M. R., Richards, S., Forney, C. R., Wright, J., Leong, M. M., Murray-Nerger, L. A., Gewurz, B. E., Kaufman, K. M., Harley, J. B., Zhao, B., Miller, W. E., Kottyan, L. C., Weirauch, M. T.
10.1101/2024.04.12.588762 — Posted: 2024-04-13 — Discussion: 2025-08-26  eLife
Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR
Akhtar, F., Ruiz, J. H., Liu, Y.-G., Resendez, R. G., Feliers, D., Morales, L. D., Diaz-Badillo, A., Lehman, D. M., Arya, R., Alvarenga, J. C. L., Blangero, J., Duggirala, R., Mummidi, S.
10.1101/2023.10.31.564937 — Posted: 2023-11-02 — Discussion: 2025-08-26  eLife
DNA methylation insulates genic regions from CTCF loops near nuclear speckles
Roseman, S. A., Siegenfeld, A. P., Lee, C., Lue, N. Z., Waterbury, A. L., Liau, B. B.
10.1101/2023.07.26.550645 — Posted: 2023-07-26 — Discussion: 2025-08-06  eLife

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