Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

929 Articles

Stabilisation of β-Catenin-WNT signalling by USP10 in APC-truncated colorectal cancer drives cancer stemness and enables super-competitor signalling
Reissland, M., Hartmann, O., Tauch, S., Prieto-Garcia, C., Schulte, C., Solvie, D., Loebbert, S., Jacomin, A. C., Pesic, M., Bugter, J. M., Schuelein-Voelk, C., Fuss, C., Pahor, N., Ade, C., Buck, V., Potente, M., Li, V., Beliu, G., Wiegering, A., Bitman-Lotan, E., Grossmann, T., Rosenfeldt, M., Eilers, M., Maric, H., Maurice, M. M., Greten, F., Dikic, I., Orian, A., Gallant, P., Diefenbacher, M. E.
10.1101/2023.02.10.527983 — Posted: 2023-02-13
Unique Amphipathic α-helix Drives Membrane Insertion and Enzymatic Activity of ATG3
Nishimura, T., Lazzeri, G., Mizushima, N., Covino, R., Tooze, S.
10.1101/2023.02.11.528101 — Posted: 2023-02-12
The ecdysone receptor promotes or suppresses proliferation according toligand level
Perez-Mockus, G., Cocconi, L., Alexandre, C., Aerne, B. L., Salbreux, G., Vincent, J.-P.
10.1101/2023.02.10.527985 — Posted: 2023-02-11
A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective
Ong, H. W., Liang, Y., Richardson, W., Lowry, E. R., Wells, C. I., Chen, X., Silvestre, M., Dempster, K., Silvaroli, J. A., Smith, J. L., Wichterle, H., Pabla, N. S., Ultanir, S. K., Bullock, A. N., Drewry, D., Axtman, A. D.
10.1101/2023.02.09.527935 — Posted: 2023-02-11
A low-cost device for cryoanesthesia of neonatal rodents
Jamieson, B. B., Konstantinou, G., Cano-Ferrer, X., de Launoit, E., Renier, N., Imbert, A., Kohl, J.
10.1101/2022.06.09.495437 — Posted: 2023-02-09
Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
Tomic, G., Sheridan, C., Refermat, A. Y., Baggelaar, M. P., Sipthorp, J., Sudarshan, B., Ocasio, C. A., Suarez-Bonnet, A., Priestnall, S. L., Herbert, E., Tate, E. W., Downward, J.
10.1101/2023.02.08.527637 — Posted: 2023-02-09
Enzyme-less nanopore detection of post-translational modifications within long polypeptides
Martin-Baniandres, P., Lan, W.-H., Board, S., Romero-ruiz, M., Garcia-Manyes, S., Qing, Y., Bayley, H.
10.1101/2023.02.09.527483 — Posted: 2023-02-09
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M., Baltussen, L. L., Lopes, A. T., Qiu, Y., Sirvio, L., Mihaylov, S. R., Claxton, S., Richardson, J. C., Lignani, G., Ultanir, S. K.
10.1101/2022.11.24.517538 — Posted: 2023-02-08
Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Caswell, D. R., Mayekar, M. K., Gui, P., Law, E. K., Vokes, N. I., Ruiz, C. M., Dietzen, M., Angelova, M., Bailey, C., Pich, O., Bakker, B., Wu, W., Humpton, T. J., Kerr, D. L., Hill, W., Lu, W.-T., Haderk, F., Blakely, C. M., Bakir, M. A., Nagano, A., Gimeno-Valiente, F., Weeden, C., Rowan, A., McCoach, C. E., Almeida, B., Green, M., Gomez, C., Gini, B., Nanjo, S., Barbosa, D., Moore, C., Przewrocka, J., Gronroos, E., Priestnall, S., Suarez-Bonnet, A., Zverev, C., Lighterness, S., Cormack, J., Olivas, V., Cech, L., Rule, B., Ashford, P., Durfee, C., Temiz, N. A., Tan, L., Larson, L. K., Argyr
10.1101/2020.12.18.423280 — Posted: 2023-02-05
PerTurboID: A targeted in situ method to measure changes in a local protein environment reveals the impact of kinase deletion on cytoadhesion in malaria causing parasites
Davies, H., Belda, H., Broncel, M., Dalimot, J., Treeck, M.
10.1101/2023.02.02.526785 — Posted: 2023-02-03

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