Channel:  Francis Crick Institute

1,225 Articles

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Lonafarnib Partially Reverses Cardiac Senescence in Human and Mouse Progeria Models via Autophagy Activation
Monteiro, L. M., Pitrez, P. R., Correira-Santos, S., Dark, N., Santinha, D., Aveleira, C., Townsend, M., Taylor, J., Nissan, X., Sardao, V., Cortes, L., Mitter, R., Marino, A., Sousa-Soares, C., Ribeiro, R., Smith, J. C., Logarinho, E., Ori, A., Bernardo, A. S., Ferreira, L.
10.1101/2025.06.27.661680 — Posted: 2025-07-02
Spatiotemporal mapping of the contractile and adhesive forces sculpting early C. elegans embryos
Yamamoto, K., Ichbiah, S., Perez, M., Borrego-Pinto, J., Delbary, F., Goehring, N., Turlier, H., Charras, G.
10.1101/2023.03.07.531437 — Posted: 2025-07-01
Vinorelbine enhances the efficacy of GM-CSF-armed oncolytic vaccinia virus in a preclinical model of ovarian high grade serous carcinoma
Drymiotou, S., Queval, C. J., Tyson, K. E., Sheach, L. A., Postigo, A., Rosa, I. D., Ennis, D. P., Howell, M., McNeish, I. A., Way, M.
10.1101/2025.02.04.636413 — Posted: 2025-06-30
Sensitizing Immune-Refractory Ovarian Tumors via p53 Mutation-Tailored Immunotherapy
Chatterjee, R., Simoni-Nieves, A., Truong, A., Lindzen, M., Ozmen, F., Cherry, C., Zwicky, P., Mukherjee, S., Selvadurai, B.-R., Salame, T. M., Gupta, N., Giri, S., Kramarski, L., Avraham, Y., Weizman, E., Ozmen, T., Noronha, A., Chakrabarti, P., Ramesh-Kumar, D., Downward, J., Dahan, R., Amit, I., Velculescu, V., Brenton, J., Mills, G., Oren, M., Yarden, Y.
10.1101/2025.06.23.661120 — Posted: 2025-06-27
VISIBLE: An imaging-driven system for sampling, biofabrication, and manipulation of complex biological models
Joshi, S., Moreno-Gonzalez, C., Suklai, P., Carraro, E., Ratcliffe, C. D. H., Boezio, G. L. M., Konstantinou, G., Cano-Ferrer, X., Hagemann, C., Kavanagh, T., Ameer-Beg, S., Imbert, A., Sahai, E., Tedesco, F. S., Serio, A.
10.1101/2025.06.12.659321 — Posted: 2025-06-27
A Statistical Framework for Robust and Reproducible BioImage Analysis
Barry, D. J., Marcotti, S., Gerontogianni, L., Kelly, G.
10.1101/2025.02.10.637409 — Posted: 2025-06-24
Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell
Jones, D., Belda, H., Broncel, M., Fuchs, G., Anaguano, D., Nofal, S. D., Treeck, M.
10.1101/2025.05.14.653932 — Posted: 2025-06-21
The evolution of gene regulatory programs controlling gonadal development in primates
Trost, N., Fallahshahroudi, A., Sarropoulos, I., Schneider, C., Schmidt, J., Mbengue, N., Wolff, E., Drummer, C., Frömel, R., Lisgo, S., Murat, F., Sepp, M., Cardoso-Moreira, M., Behr, R., Kaessmann, H.
10.1101/2025.06.17.659946 — Posted: 2025-06-19
Overnight circuit remodelling drives juvenile alloparental care
Jamieson, B. B., Chen, M. X., Liang, S., El Rasheed, L. S. H., Chattey, G. M. K., Kohl, J.
10.1101/2025.06.13.659524 — Posted: 2025-06-15
SARS-CoV-2 envelope protein induces LC3 lipidation via the V-ATPase-ATG16L1 axis
Figueras-Novoa, C., Timimi, L. J., Marcassa, E., Taveira-Marques, R., Adams, L., Jiang, M., Wu, M. Y., Montaner, B., Ng, K., De Lorenzo, G., Furnon, W., Cowton, V. M., Upfold, N., Kassiotis, G., Harvey, R., Patel, A. H., Howell, M., Ulferts, R., Beale, R.
10.1101/2025.06.12.659257 — Posted: 2025-06-13

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