Channel:  Harvard Program in Therapeutic Sciences

114 Articles

Persistent Neurological Deficits in Mouse PASC Reveal Antiviral Drug Limitations
Verma, A. K., Lowery, S., Lin, L.-C., Duraisami, E., Abrahante, J. E. K., Qiu, Q., Hefti, M. M., Yu, R. C., Albers, M. W., Perlman, S.
10.1101/2024.06.02.596989 — Posted: 2024-06-03
Spatial Profiling of Metals through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging
Stopka, S., Bodineau, C., Baquer, G., Lin, J.-R., Hossain, M. A., Regan, M. S., Ruiz, D. F., Fletcher, S.-M., Pourquie, O., Lutsenko, S., Payne, C., Agar, J. N., Mazitschek, R., McDannold, N., Sorger, P. K., Santagata, S., Agar, N.
10.1101/2024.05.22.594980 — Posted: 2024-05-23
Efficient and Robust Search of Microbial Genomes via Phylogenetic Compression
Brinda, K., Lima, L., Pignotti, S., Quinones-Olvera, N., Salikhov, K., Chikhi, R., Kucherov, G., Iqbal, Z., Baym, M.
10.1101/2023.04.15.536996 — Posted: 2024-05-11
Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter
Baker, G. J., Novikov, E., Zhao, Z., Vallius, T., Davis, J. A., Lin, J.-R., Muhlich, J. L., Mittendorf, E. A., Santagata, S., Guerriero, J. L., Sorger, P. K.
10.1101/2023.11.01.565120 — Posted: 2024-03-22
Sendai virus persistence questions the transient naive reprogramming method for iPSC generation
De Los Angeles, A., Hug, C. B., Gladyshev, V. N., Church, G. M., Velychko, S.
10.1101/2024.03.07.583804 — Posted: 2024-03-12
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
Do, B. T., Hsu, P. P., Vermeulen, S. Y., Wang, Z., Hirz, T., Abbott, K. L., Aziz, N., Replogle, J. M., Bjelosevic, S., Paolino, J., Nelson, S., Block, S., Darnell, A. M., Ferreira, R., Zhang, H., Milosevic, J., Schmidt, D. R., Chidley, C., Harris, I. S., Weissman, J. S., Pikman, Y., Stegmaier, K., Cheloufi, S., Su, X. A., Sykes, D. B., Vander Heiden, M. G.
10.1101/2022.08.16.503984 — Posted: 2024-01-09
Diverse and Abundant Phages Exploit Conjugative Plasmids
Quinones-Olvera, N., Owen, S. V., McCully, L. M., Marin, M. G., Rand, E. A., Fan, A. C., Dosumu, O. J. M., Paul, K., Castano, C. E. S., Petherbridge, R., Paull, J. S., Baym, M.
10.1101/2023.03.19.532758 — Posted: 2023-12-21
Cell Spotter (CSPOT): A machine-learning approach to automated cell spotting and quantification of highly multiplexed tissue images
Nirmal, A. J., Yapp, C., Santagata, S., Sorger, P.
10.1101/2023.11.15.567196 — Posted: 2023-11-17
SpatialCells: Automated Profiling of Tumor Microenvironments with Spatially Resolved Multiplexed Single-Cell Data
Wan, G., Maliga, Z., Yan, B., Vallius, T., Shi, Y., Khattab, S., Chang, C., Nirmal, A. J., Yu, K.-H., Liu, D., Lian, C. G., DeSimone, M. S., Sorger, P. K., Semenov, Y. R.
10.1101/2023.11.10.566378 — Posted: 2023-11-14
2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer
Coy, S., Cheng, B., Lee, J. S., Rashid, R., Browning, L., Xu, Y., Chakrabarty, S. S., Yapp, C., Chan, S., Tefft, J. B., Spektor, A., Ligon, K. L., Baker, G. J., Pellman, D., Sorger, P. K., Santagata, S.
10.1101/2023.11.07.566063 — Posted: 2023-11-11

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