Channel: Morgridge Institute

This collection includes bioRxiv and medRxiv papers from authors at Morgridge Institute.

160 Articles

Cellpose as a reliable method for single-cell segmentation of autofluorescence microscopy images

Riendeau, J. M., Gillette, A., Contreras Guzman, E., Costa Cruz, M., Kralovec, A., Udgata, S., Schmitz, A., Deming, D. A., Cimini, B. A., Skala, M. C.

10.1101/2024.06.07.597994 — Posted: 2024-06-10

Diminished Immune Cell Adhesion in Hypoimmune ICAM-1 Knockout Pluripotent Stem Cells

Saha, S., Haynes, W. J., Del Rio, N., Young, E. E., Zhang, J., Seo, J., Huang, L., Holm, A. M., Blashka, W., Murphy, L., Scholz, M., Henrichs, A., Suresh Babu, J., Steill, J., Stewart, R. E., Kamp, T. J., Brown, M. E.

10.1101/2024.06.07.597791 — Posted: 2024-06-09

Autofluorescence lifetime flow cytometry with time-correlated single photon counting

Samimi, K., Pasachhe, O., Guzman, E. C., Riendeau, J., Gillette, A. A., Pham, D. L., Wiech, K. J., Moore, D. L., Skala, M. C.

10.1101/2024.05.15.594394 — Posted: 2024-05-18

Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer

Lancaster, N. M., Sinitcyn, P., Forny, P., Peters-Clarke, T. M., Fecher, C., Smith, A. J., Shishkova, E., Arrey, T. N., Pashkova, A., Robinson, M. L., Arp, N., Fan, J., Hansen, J., Galmozzi, A., Serrano, L. R., Rojas, J., Gasch, A. P., Westphall, M. S., Stewart, H., Hock, C., Damoc, E., Pagliarini, D. J., Zabrouskov, V., Coon, J. J.

10.1101/2023.11.21.568149 — Posted: 2024-05-16

Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistence

Cappabianca, D., Pham, D., Forsberg, M. H., Bugel, M., Tommasi, A., Lauer, A., Vidugiriene, J., Hrdlicka, B., McHale, A., Sodji, Q., Skala, M. C., Capitini, C. M., Saha, K.

10.1101/2024.01.31.575774 — Posted: 2024-03-19

Label free metabolic imaging to enhance the efficacy of Chimeric Antigen Receptor T cell therapy

Pham, D. L., Cappabianca, D., Forsberg, M., Weaver, C., Mueller, K. P., Tommasi, A., Vidugiriene, J., Lauer, A., Sylvester, K., Bugel, M., Capitini, C. M., Saha, K., Skala, M. C.

10.1101/2024.02.20.581240 — Posted: 2024-02-23

Macrophages undergo functionally significant reprogramming of nucleotide metabolism upon classical activation

John, S. V., Seim, G. L., Erazo-Flores, B. J., Steill, J., Freeman, J., Votava, J. A., Arp, N. L., Qing, X., Stewart, R., Knoll, L. J., Fan, J.

10.1101/2023.12.27.573447 — Posted: 2024-02-23

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

Gao, A. W., El Alam, G. W., Zhu, Y., Li, W., Katsyuba, E., Sulc, J., Li, T., Li, X., Overmyer, K. A., Lalou, A., Mouchiroud, L., Bou Sleiman, M., Cornaglia, M., Morel, J.-D., Houtkooper, R., Coon, J., Auwerx, J.

10.1101/2024.01.15.575638 — Posted: 2024-01-16

ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism

Rashan, E. H., Bartlett, A. K., Khana, D. B., Zhang, J., Jain, R., Smith, A. J., Baker, Z. N., Cook, T., Caldwell, A., Chevalier, A. R., Pfleger, B. F., Yuan, P., Amador-Noguez, D., Simcox, J. A., Pagliarini, D. J.

10.1101/2024.01.09.574893 — Posted: 2024-01-09

Naive primary neutrophils play a dual role in the tumor microenvironment

Babatunde, K. A., Datta, R., Hendikse, N. W., Ayuso, J. M., Huttenlocher, A., Skala, M. C., Beebe, D. J., Kerr, S. C.

10.1101/2023.09.15.557892 — Posted: 2024-01-03

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