Channel: Yale University

This collection includes bioRxiv and medRxiv papers from authors at Yale University.

4848 Articles

Predicting Disease-Specific Histone Modifications and Functional Effects of Non-coding Variants by Leveraging DNA Language Models

Wang, X., Pan, T., Chen, S., Webb, G., Jiang, Y., Rozowsky, J., Gerstein, M., Song, J.

10.1101/2025.06.15.659749 — Posted: 2025-06-17

Image-Based Meta- and Mega-Analysis (IBMMA): A Unified Framework for Large-Scale, Multi-Site, Neuroimaging Data Analysis

Steele, N., Morey, R., Hussain, A., Russell, C., Suarez-Jimenez, B., Pozzi, E., Jameei, H., Schmaal, L., Veer, I., Waller, L., Jahanshad, N., Thomopoulos, S., Salminen, L., Olff, M., Frijling, J., Veltman, D., Koch, S., Nawijn, L., van Zuiden, M., Wang, L., Zhu, Y., Li, G., Stein, D., Ipser, J., Neria, Y., Zhu, X., Ravid, O., Zilcha-Mano, S., Lazarov, A., Huggins, A., Stevens, J., Ressler, K., Jovanovic, T., van Rooij, S., Fani, N., Mueller, S., Hudson, A., Daniels, J., Sierk, A., Manthey, A., Walter, H., van der Wee, N., van der Werff, S., Vermeiren, R., Schmahl, C., Herzog, J., Rektor, I., i

10.1101/2025.06.16.657725 — Posted: 2025-06-17

Unanticipated Global Emergence of Multiple Pneumocystis jirovecii Mutants Selected by Mycophenolic Acid Driving Increasing Outbreaks in Solid Organ Transplant Recipients

Ma, L., Hao, M., Chang, W., Deng, X., Sun, J., Azar, M. M., Fehr, T., Gianella, S., Goto, N., Helweg-Larsen, J., Huang, L., Mueller, N. J., Oka, S., Peng, L., Rostved, A., Sing, A., Walsh, L. F., Yazaki, H., Pan, L., Sassi, M., Wang, Y., Spielman, B., Konrad, R., Hirzel, C., Cusini, A., Handley, G., Hedstrom, L., Imamichi, T., Kovacs, J. A.

10.1101/2025.06.17.25328583 — Posted: 2025-06-17

Leveraging pleiotropy to improve genetic risk prediction across diseases

Hu, J., Zhou, G., Zhao, H.-y., DeWan, A. T.

10.1101/2025.06.16.25329688 — Posted: 2025-06-16

The capsule and genetic background, rather than specific individual loci, strongly influence in vitro pneumococcal growth kinetics

Chaguza, C., Arends, D. W., Lo, S. W., Putri, I. H., York, A., Lees, J. A., Wyllie, A. L., Weinberger, D. M., Bentley, S. D., de Jonge, M. I., Cremers, A. J. H.

10.1101/2024.12.05.627025 — Posted: 2025-06-15

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

De Man, R., Cai, Z., Doddaballapur, P., Guerrera, N., Lin, L., Justet, A., Abu Hussein, N. S., Cavinato, C., Raredon, M. S. B., Heerdt, P., Singh, I., Yan, X., Kang, M.-J., Bruns, D. R., Lee, P. J., Tellides, G., Humphrey, J., Kaminski, N., Ramachandra, A. B., Manning, E. P.

10.1101/2025.06.10.658632 — Posted: 2025-06-15

A connectomic resource for neural cataloguing and circuit dissection of the larval zebrafish brain

Petkova, M. D., Januszewski, M., Blakely, T., Herrera, K. J., Schuhknecht, G. F. P., Tiller, R., Choi, J., Schalek, R. L., Boulanger-Weil, J., Peleg, A., Wu, Y., Wang, S., Troidl, J., Kumar Vohra, S., Wei, D., Lin, Z., Bahl, A., Tapia, J. C., Iyer, N., Miller, Z. T., Hebert, K. B., Pavarino, E. C., Taylor, M., Deng, Z., Stingl, M., Hockling, D., Hebling, A., Wang, R. C., Zhang, L. L., Dvorak, S., Faik, Z., King, K. I., Goel, P., Wagner-Carena, J., Aley, D., Chalyshkan, S., Contreas, D., Li, X., Muthukumar, A. V., Vernaglia, M. S., Tapia Carrasco, T., Melnychuck, S., Yan, T., Dalal, A., DiMarti

10.1101/2025.06.10.658982 — Posted: 2025-06-15

Transient AMPK activation by nutrient stress of high fat diet preserves cardiac electrophysiological stability and protects against arrhythmias

Rudokas, M. W., McKay, M., Wu, X., Granger, J. M., Williams, Y., Bogner, M., Kang, T., Seyfried, A., Toksoy, Z., Cacheux, M., Young, L. H., Akar, F. G.

10.1101/2025.06.11.658631 — Posted: 2025-06-15

Characterization of neuronal ensembles in a model of dual reward conditioned place preference

Flom, L. T., Sandum, K., Hodgins, S., Johnson-Noya, S., Crouse, J., Zhang, Z., Bobadilla, A. C.

10.1101/2025.06.11.659163 — Posted: 2025-06-15

Two Specialized Intrinsic Cardiac Neuron Types Safeguard Heart Homeostasis and Stress Resilience

Xu, Q. J., Applegate, M. C., Hsu, I.-U., Kogan, R. P., Hafez, O. A., Wang, R. L., Rios Coronado, P. E., Young, L. H., Zeng, X., Zhang, L., Chang, R.

10.1101/2025.06.13.659555 — Posted: 2025-06-15

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